Navigation Links
Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

Mechanical 'artificial hearts' can be used to return severely failing hearts to their normal function, potentially removing the need for heart transplantation, according to new research.

The mechanical devices, known as Left Ventricular Assist Devices (LVADs), are currently used in patients with very severe heart failure whilst they await transplantation. The new study, published in the New England Journal of Medicine, shows that using an LVAD combined with certain drug therapies can shrink the enlarged heart and enable it to function normally once the LVAD is removed.

For the study, researchers from Imperial College London and the Royal Brompton and Harefield NHS Trust gave the full combination therapy to 15 severely ill patients. Of these 15, 11 recovered. Of these, 88 percent were free from recurrence of heart disease five years later. Their quality of life was measured as being at nearly normal.

Dr Emma Birks, from the Heart Science Centre at Imperial and the Royal Brompton and Harefield NHS Trust, and lead author of the study, said: "Donor heart transplant has for many years been the gold standard in the treatment of those with severe heart failure. It has proven greatly successful but is not without its shortcomings ?particularly the shortage of donor hearts and the risk of organ rejection.

"This therapy has the potential to ease the pressure on the waiting list while also offering patients a better alternative to a donor heart ?their own, healthy heart," she added.

Professor Sir Magdi Yacoub, from the Heart Science Centre at Imperial and the Royal Brompton and Harefield NHS Trust, said: "We are impressed by the dramatic, sustained improvement in the condition of these severely ill patients and we believe that this is due to the additive effects of the particular combination therapy used. The improvement observed was far greater than what has been reported to date for any other therapy in patients with severe,
'"/>

Source:Imperial College London


Page: 1 2

Related biology news :

1. UT Southwestern researchers find gene mutation that leads to broken hearts
2. Transgenic plants remove more selenium from polluted soil than wild plants, new tests show
3. Rare surgery performed to remove pancreas, prevent diabetes
4. First technology to remove prions that cause vCJD from blood launched
5. New UD technology removes viruses from drinking water
6. UCSD team discovers specialized, rare heart stem cells in newborns
7. Single stem cells from bone heal a broken heart
8. Python a hearty eater
9. Columbia study shows widely used artery clearing device does not help patients during heart attack
10. Researchers reveal secret of key protein in brain and heart function
11. Stem cell therapy successfully treats heart attack in animals
Post Your Comments:
(Date:8/19/2014)... infants born with neonatal abstinence syndrome (NAS) secondary ... time going through withdrawal than others, but the ... and epigenetic (when genes are turned on or ... factors, researchers at Boston University School of Medicine ... first of its kind study to identify some ...
(Date:8/19/2014)... students in college biology and other science courses ... quantitative ways, and now they have a new ... the Life Sciences," published this month by Princeton ... Institute for Mathematical and Biological Synthesis (NIMBioS), teaches ... can be used to explore and explain biological ...
(Date:8/19/2014)... been awarded a nearly $40,000 grant from the National ... of the National Park Service (NPS) and U.S. Department ... study of the energy efficiency and cost effectiveness of ... climates. , Radiant barriers are reflective thermal insulations commonly ... thereby reducing the amount of heat emitted in the ...
Breaking Biology News(10 mins):In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome 2New textbook introduces undergraduates to mathematics for the life sciences 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 3
... research published online in The FASEB Journal ( ... London have devised a one-two punch to stop HIV. First ... virus when used as a microbicide. Then the report shows ... quantities large enough to make it affordable for people in ...
... the problem of pod shatter in brassica crops such as ... prone to shatter, causing a 10-25% loss of seeds and ... a hormone in a specific region of the fruit, we ... Arabidopsis , completely sealing the seeds inside," says Dr ...
... for the Environment has awarded four new Environmental Venture ... practical solutions promoting global sustainability. Four Stanford University faculty ... next two years to tackle environmental challenges, from the ... California. Thirty-three ...
Cached Biology News:Scientists develop a new HIV microbicide -- and a way to mass produce it in plants 2Shatter-resistant brassicas 2Stanford's Woods Institute awards new round of Environmental Venture Projects 2Stanford's Woods Institute awards new round of Environmental Venture Projects 3Stanford's Woods Institute awards new round of Environmental Venture Projects 4
(Date:8/19/2014)... BURNIE, Md. , Aug. 19, 2014 ... clinical research industry, recently announced the formation of the ... pleased to announce the addition of Dr. William ... Photo - http://photos.prnewswire.com/prnh/20140818/136957 The ... across a variety of therapeutic areas and set strategic ...
(Date:8/19/2014)... Sales Horizons, a leader in sales training, ... skills training course to help companies develop clinical ... spend the majority of their time on client sites ... physician practice – providing support and education to both ... Horizons believes clinical staff are and should be considered ...
(Date:8/18/2014)... FREDERICK, Md. , Aug. 18, 2014 ... the maker of advanced consumer medical devices ... Kotak was interviewed by CEOLIVE.TV as ... The entire interview is available at ... interview Dr. Kotak explains to investors the ...
(Date:8/18/2014)... , August 18, 2014 ... Transparency Market Research "Life Science Reagents Market(Products- PCR ... Electrophoresis, Chromatography, In-Vitro Diagnostic Reagents and Others; End ... Institutions, Clinical Laboratories, and Forensic Laboratories)- Global Industry ... - 2019", the global life science reagents market ...
Breaking Biology Technology:CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 2CSSi Appoints Dr. William E. Gannon, Jr. to Newly Formed Medical and Clinical Advisory Board 3Sales Horizons Launches a New Online Sales Training Course for MedTech Clinical Staff to Develop Their Sales Skills 2Sales Horizons Launches a New Online Sales Training Course for MedTech Clinical Staff to Develop Their Sales Skills 3BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 2BioElectronics EVP Dr. Deepak Kotak Interviewed on CEO Live 3Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 2Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 3Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 4Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 5
... software release for the V and Vmax includes a range of ... due to the effects of speech, language and learning disabilities, ease ... applications outside the V/Vmax communication software. , ... Pittsburgh ...
... significantly,simplifies the study of Global Methylation with results in half ... ... current methods, ST. LOUIS, Oct. 30 Sigma-Aldrich (Nasdaq:,SIAL) ... research http://www.sigma-aldrich.com/mdq1 . The,Methylated DNA Quantification Kit employs a ...
... turned into bioethanol, a renewable fuel that can be produced ... or diesel. This gives the olive processing industry an opportunity ... in olive stones it generates every year and sets a ... from the Universities of Jan and Granada in Spain show ...
Cached Biology Technology:DynaVox Releases Software Version 1.05 for DynaVox V and Vmax 2DynaVox Releases Software Version 1.05 for DynaVox V and Vmax 3Sigma-Aldrich Introduces Methylated DNA Quantification Technology for Epigenetic Research 2Sigma-Aldrich Introduces Methylated DNA Quantification Technology for Epigenetic Research 3Powered by olive stones? Turning waste stones into fuel 2
...
... The Helios gene gun optimization kit ... in optimizing parameters affecting particle delivery with ... 0.25 g each of 0.6 micrometer, 1.0 ... included is a cartridge kit, that provides ...
... Cellerity is Tecans fully automated solution ... cost-effective, fast automation for cell-line maintenance, ... a modular system built upon standard, ... modified liquid handling configuration capable of ...
... Expression (SAGE) is a powerful genome-wide ... cost-effective outsourcing solution for sequencing of ... SAGE sequencing service provides our clients ... Phred20 read lengths (40 SAGE tags ...
Biology Products: