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Measurement Challenges In Detecting Cancer Biomarkers

artner referral arm (telling partners to get treated). Men in the patient-delivered partner treatment arm were also less likely than men in either of the other two arms to have unprotected sex before their partners were treated for STDs. Finally, men in the patient-delivered partner treatment and booklet-enhanced arms were far less likely than men in the standard partner referral arm to re-test positive for chlamydia and gonorrhea at follow-up.

Patient-delivered partner treatment is not yet used widely due mainly to fears that are largely unfounded, said Patricia Kissinger, PhD, of Tulane University School of Public Health and Tropical Medicine and lead author of the article. "Clinicians have fears of legal liability, particularly if the partners have side effects. In three randomized trials [on patient-delivered partner treatment] that have been conducted, there have been no reports of adverse events," Dr. Kissinger said. "Particularly for chlamydia, there is little chance of side effects with azithromycin," the antibiotic given to patients in patient-delivered partner treatment.

Another worry that clinicians may have about patient-delivered partner treatment is "that partners will not get treated and counseled for other [STDs] they may have, such as HIV" if they receive treatment for chlamydia or gonorrhea, Dr. Kissinger said. "While this is a valid concern, the alternative to not doing patient-delivered partner treatment is to rely on the patient to refer the partners. We know that that results in less than 50 percent of the partners getting treated. So those partners were probably not going to get those services anyway."

The relative success of patient-delivered partner treatment probably lies in the fact that, with the more traditional methods, patients just had to admit to their partners that there was a problem. With the new method, the patients can offer their partners a solution. "The patients really like the empowerment of being abl
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