Navigation Links
Mayo discovers protein as potential tactic to prevent tumors

o another cellular protein, FOXO1, switching it on as the initial link in a signal that tells the cell to set itself up for apoptosis. CDK2 adds phosphorylation to a specific serine residue on the chain of amino acids that make up FOXO1. In case of robust errors found in the genetic code, CDK2 signals FOXO1 to explicitly call for the cell to produce a set of proteins leading to apoptosis.

"If the cell has minor alterations in the DNA code that can be repaired, those repairs are made," says first author Haojie Huang, Ph.D. "If the genetic message cannot be repaired, our studies show that CDK2 can initiate the steps necessary for cells to order the production of genes involved with cell death, and the errant cell dies without propagating its damaging genetic message to progeny cells of its own."

"As patients and their physicians seek to control or cure tumors, research is providing new approaches to limiting cancer from growing and spreading," Dr. Tindall said. "With this new understanding of the biology driven by critical dual functions of CDK2, the cancer community can focus on ways to regulate a mechanism that the cell contains to prevent damaged genetic messages from being inherited and spread in proliferating tumor cells."


'"/>

Source:Mayo Clinic


Page: 1 2

Related biology news :

1. UCSD team discovers specialized, rare heart stem cells in newborns
2. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
3. MIT chemist discovers secret behind natures medicines
4. Mayo Clinic collaboration discovers protein amplifies DNA injury signals
5. Expedition discovers marine treasures
6. Team discovers possible universal strategy to combat addiction
7. Nobelist discovers antidepressant protein in mouse brain
8. Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes
9. Contrary to common wisdom, scientist discovers some mammals can smell objects under water
10. U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
11. LSU professor discovers new species
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mayo discovers protein potential tactic prevent tumors

(Date:10/16/2014)... women experienced improvements in vaginal atrophy, with no ... after 12 weeks of daily 10 milligram (mg) ... supplement previously shown to help relieve certain menopause ... reported in a poster at the North American ... "These data documented improved vaginal epithelium, without significant ...
(Date:10/15/2014)... ,Models of Life, is a non-traditional biophysics textbook and ... book is a journey of discovery into biological systems ... and biological regulation. It is about how our genes ... between the billions of cells in an organism. It ... between principles, which can be found on both large ...
(Date:10/15/2014)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... growing mobile commerce market releases photos and video of the recent ... October 13 th . Gino Pereira , ... angel investor Mr. Chad A. Verdi rang the bell.  ... his investors and employees "for their work and dedication in bringing ...
Breaking Biology News(10 mins):S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2New book about life as seen from physics 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
... Nov. 6, 2013 /PRNewswire-iReach/ -- IdentiSys Inc., North ... identification, card issuance, emergency response, and access control security ... the world,s leader in Customer and Patient Experience Management ... system from Qmatic to the marketplace and will be ...
... phytochemicals called polyphenols, which have been reported by a growing ... health benefits. A new study by researchers at the University ... This new research, published today in the journal ... long-term wild blueberry diets may help improve or prevent pathologies ...
... written to describe proteins, as the M. C. Escher-esque ... to carry out its specific responsibilities. Technology,s workhorse for ... a beam of x-rays sent through a crystallized protein ... pattern of dots that can be reconstructed by computer ...
Cached Biology News:IdentiSys brings Qmatic Q-Guide Queuing Systems to the North American market 2IdentiSys brings Qmatic Q-Guide Queuing Systems to the North American market 3Health benefits of wild blueberries abound: Study 2Bringing out the best in X-ray crystallography data 2
(Date:10/20/2014)... Convey Computer , the leader in hybrid-core ... University won first place in the 2014 MemoCODE ... team’s solution achieved the highest overall performance in the ... finisher. , Experts from all segments of the commercial ... using a variety of design tools, hardware and software. ...
(Date:10/20/2014)... PureTech , a science and technology development ... today the closing of a $55 million growth ... a $120 Billion group of funds. The funding ... forward and to advance new healthcare related products ... really go for the big ideas that can ...
(Date:10/19/2014)... 2014 OCTOBER 20-22, 2014: ... ABIM will take place at the ... ABIM 2014 is now available at ... companies and organizations from all over the ... on the latest products and developments on ...
(Date:10/19/2014)... 2014 The report "Chocolate, Cocoa Beans, ... Prices, Geography Trend and Forecast (2011 - 2016)," ... geography and studies the major market drivers, restraints, and ... and Asia. , The global chocolate market is expected ... in 2016 at an estimated CAGR of 2.7% from ...
Breaking Biology Technology:Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4
... , , , , Agencourt offers ... identification of SNP loci. Our SeeSNP service , is based ... to sequence over 20 million Phred20 bases a day. Features that set our ... , SPRItechnology for increased sequencing performance and ...
... , , , , , , ... throughput capacity of, 25,000 end reads per day. The key features of our ... Industry leading sequence quality , ... Fully-automated, GLP-compliant facility , , ...
... , , , , , ... of purifying amplicons as small as 100bp. AMPure yields high quality PCR , ... or filtration steps. The protocol can be easily automated or performed , ... , EFFICIENT PCR PURIFICATION ...
Cached Biology Technology:SEESNP DISCOVERY 2END SEQUENCING 2AMPURE PURIFICATION SYSTEM 2AMPURE PURIFICATION SYSTEM 3
... Anti-Major DNA-binding protein(DBP). Protein ... NP_001343 ELISA titre using ... Suggested conditions for Western Blot: ... buffer, and HRP conjugated anti-Rabbit IgG should ...
Collected from sexually mature, mixed sex, mixed breed guinea pigs. Pricing: $120/unit for 1 - 10 units...
SEQUENASE PCR PRODUCT PRE-SEQU, 1 EA. Category: SEQUENASE....
Mouse monoclonal [IFR0104] to Salmonella enteriditis ( Abpromise for all tested applications)....
Biology Products: