Navigation Links
MatBase -- A new transcription factor knowledge base released by Genomatix

Genomatix Software GmbH, a pioneer and leader in the analysis of eukaryotic transcriptional regulation, releases MatBase, a knowledge base of transcription factors (TF).

It contains genomic TF binding sites and protein binding domains, related literature, more than 27.000 known TF ?gene interactions, experimentally verified complexes with other TFs (promoter modules), and weight matrix descriptions for the DNA binding sites of TFs.In contrast to other available TF databases, each entry in MatBase is thoroughly tested for quality and usability for functional analysis of DNA regulatory regions.

"We have developed our in-house TF database now for more than a decade", says Kornelie Frech, Genomatix´Head of Biological Databases." Quality is essential for all further downstream analyses. Our quality standards were the key to success for MatInspector, the de facto gold standard in gene promoter analysis, used by more than 31.000 scientists around the globe today. More than 80% of our matrices match less than once in 1000 base pairs of random DNA sequences", she continues.

MatInspector employs the weight matrix descriptions as contained in MatBase for performing TF binding site search in regulatory DNA sequences. Each single matrix is optimized for a minimum number of false positive results in non regulatory DNA.


'"/>

Source:Genomatix Software GmbH


Page: 1

Related biology news :

1. Modification of program enables prediction of gene transcription
2. NYU chemists use computer simulation to enhance understanding of DNA transcription
3. Discovering the first steps in transcription-coupled repair
4. When it comes to gene transcription, random pauses aren’t quite so random, study finds
5. Non-coding RNAs help silence the mammalian transcription
6. Nanotech tools yield DNA transcription breakthrough
7. Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
8. Cracking the olfactory code in bees
9. The first impact factor for PLoS Biology ?13.9
10. Open Access journals get impressive impact factors
11. Novel plague virulence factor identified
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
(Date:4/5/2017)... 2017 KEY FINDINGS The global ... a CAGR of 25.76% during the forecast period of ... factor for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is ... geography. The stem cell market of the product is ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 ... London (ICR) and University of ... prognostic tool to risk-stratify patients with multiple myeloma (MM), in ... nine . The University of Leeds ... by Myeloma UK, and ICR will perform the testing services ...
(Date:10/11/2017)... TX (PRWEB) , ... October 11, 2017 , ... ... August compared the implantation and pregnancy rates in frozen and fresh in ... contribution of progesterone and maternal age to IVF success. , After comparing the ...
(Date:10/10/2017)... ... ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled a ... new look is part of a transformation to increase awareness, appeal to new markets ... It will also expand its service offering from its signature gourmet cooking classes and ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
Breaking Biology Technology: