Navigation Links
Mass production of human papillomavirus could lead to gains against cervical cancer

Researchers may be on the verge of exploiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that enables scientists to mass-produce human papillomavirus (HPV) in the laboratory.

HPV, which exists in more than 100 forms, is the most prevalent sexually transmitted infection. Transmission of HPV can also occur non-sexually. According to the Centers for Disease Control and Prevention, approximately 20 million people in the United States are currently infected with HPV. At least 50 percent of sexually active men and women will acquire genital HPV infection at some point in their lives. By age 50, at least 80 percent of women will have acquired genital HPV infection.

Although the infection is usually harmless, certain types of HPV are responsible for nearly all cases of cervical cancer, and other types contribute to about a quarter of head and neck cancers and some skin cancers. A more common, less virulent form of the virus causes genital warts.

Using the new technique scientists can quickly produce a thousand times more infectious virus per culture dish than they could using conventional methods. Researchers are hopeful that this advance could lead to new antiviral drugs and to vaccines that would trigger the immune system to attack at an earlier stage in the virus's life cycle to stop HPV before it can replicate.

The researchers, led by Paul Ahlquist, a Howard Hughes Medical Institute investigator, published an article describing their new technique on June 13, 2005, in the early online edition of the Proceedings of the National Academy of Sciences. Ahlquist and co-authors Dohun Pyeon and Paul Lambert are at the University of Wisconsin-Madison.

The primary obstacle to producing HPV in the laboratory has been that in the early stage of its infective cycle, the virus lurks in undifferentiated basal epithelial (skin) cells, said Ahlquist. Once there, it remains in a diffuse form at
'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3

Related biology news :

1. Researchers discover key gene involved in bark beetle pheromone production
2. First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
3. UW scientists report a new method to speed bird flu vaccine production
4. New cell transplantation technique restores insulin production in diabetics
5. New molecule may aid in production of biofuels and fungi-resistant plants
6. Getting an evolutionary handle on life after reproduction
7. Olfactory system detects pheromones that control reproduction
8. The brain is broadly wired for reproduction
9. Sexual reproduction delays aging in a mammalian species
10. Sustainable farm practices improve Third World food production
11. GlycoFi announces the first production of antibodies with human glycosylation in yeast
Post Your Comments:
(Date:8/22/2014)... German . ... are fixated in a way so as to align ... and Fudan University researchers are planning on looking into ... findings are being published today in the scientific journal ... sensitive molecules. Everyone knows that at least from ...
(Date:8/22/2014)... strong antioxidants and can reduce free radical ... against oxidative stress? Jianbo Zhao and co-workers ... Medical University, China discovered that green tea ... neuronal apoptosis, indicating green tea polyphenols play ... under oxidative stress. The relevant study has ...
(Date:8/22/2014)... In 2015, American consumers will finally be able to ... Although touted as zero-emissions vehicles, most of the cars ... fossil fuel that contributes to global warming. , Now ... device that uses an ordinary AAA battery to produce ... electric current through two electrodes that split liquid water ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 3
... human genetics at Baylor College of Medicine, first published her ... starvation, sometimes resulting in a rare change that benefited the ... current issue of the journal Molecular Cell, she and her ... that this only occurs at a special time and place ...
... prediction. , Computers can predict the detailed structure of ... least some of the time, according to new studies ... which were reported in the September 16, 2005, issue ... that scientists eventually may be able to determine the ...
... led by University of California, San Diego biochemists has ... produce 10 trillion varieties of a single protein, a ... drugs. , In the September 18 advance on-line publication ... researchers describe the mechanism by which a virus that ...
Cached Biology News:Stressed cells spark DNA repair missteps and speed evolution 2Computers close in on protein structure prediction 2Computers close in on protein structure prediction 3Computers close in on protein structure prediction 4UCSD discovery may provide novel method to generate medically useful proteins 2UCSD discovery may provide novel method to generate medically useful proteins 3
(Date:8/22/2014)... Texas (PRWEB) August 23, 2014 ... the current state of the Papain industry in ... overview of the industry, including definitions, applications and ... domestic market analysis are provided with a focus ... the market. A comparison between the international and ...
(Date:8/22/2014)... in the scientific journal PLoS One , ... effect of serotonin on sensitivity to pain using ... "Serotonin is a small molecule known to be ... from the control of sleep and appetite, to ... is also popularly thought to contribute to feelings ...
(Date:8/22/2014)... 2014 The Global and China Diabetes ... the current state of the Diabetes Drug industry in ... overview of the industry, including definitions, applications and industry ... analysis are provided with a focus on history, developments, ... between the international and Chinese situation is also offered. ...
(Date:8/22/2014)... Los Angeles (PRWEB) August 22, 2014 ... for age-defying products, is in the spotlight again. ... night cream and its NeriumFirmTM Body Contouring Cream ... presented by Backstage Creations during the 66th Primetime ... the patented NAE-8® extract, third-party clinical trials show ...
Breaking Biology Technology:Papain Industry Global & China Development Trend and Proposals Analysis Research Report Available at DeepResearchReports.com 2Papain Industry Global & China Development Trend and Proposals Analysis Research Report Available at DeepResearchReports.com 3From happiness to pain: Understanding serotonin's function 2Diabetes Drugs Industry Growth Analysis in Global, China Regions Research Report Available at DeepResearchReports.com 2Diabetes Drugs Industry Growth Analysis in Global, China Regions Research Report Available at DeepResearchReports.com 3Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3
... Nectid, Inc. ( www.nectid.com ) announced today that ... patents and patents-applications to Grunenthal GmbH ( www.grunenthal.com ), ... in pain drug discovery and research. The patent portfolio ... Pain Drug Discovery program and two key drug delivery ...
... , COLUMBUS, Ohio Engineers at Ohio State University have ... from nine different angles at once to create a 3D ... that move around an object; the new lens is the ... itself. Allen Yi, associate professor of integrated systems engineering ...
... NEW YORK, March 21, 2011 Reportlinker.com announces ... available in its catalogue: ... http://www.reportlinker.com/p0459142/Global-Angiongenesis-Inhibitors-and-Stimulators-Industry.html ... Angiogenesis Inhibitors and Stimulators in US$ Million ...
Cached Biology Technology:Seeing in stereo: Engineers invent lens for 3-D microscope 2Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 2Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 3Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 4Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 5Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 6Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 7Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 8Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 9Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 10Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 11Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 12Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 13Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 14Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 15Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 16Reportlinker Adds Global Angiongenesis Inhibitors and Stimulators Industry 17
...
Improve inventory management with stainless steel red cell canisters; ensure product safety with CO2 or LN2 backup systems. A complete solution for your blood banking needs....
... oligonucleotides: PTOs are internucleotide modifications, ... backbone is replaced by a sulphur atom. ... degradation. PTOs are available as ... Oligonucleotides with thio-caps ...
Improve inventory management with stainless steel red cell canisters; ensure product safety with CO2 or LN2 backup systems. A complete solution for your blood banking needs....
Biology Products: