Navigation Links
Mapping neuron connections in the brain

The human brain contains from 10 to 100 billion neurons, and each has hundreds of connections with neighboring neurons. Making sense of these intricate connections is essential to understanding brain function, and the task is a monumental one.

Thanks to a new theoretical approach to mapping neuron connectivity published in PLoS Computational Biology by Bagrat Amirikian, a researcher at the Department of Neuroscience at the University of Minnesota, the task is now feasible. In the past, mapping connections between neurons was limited to either highly simplified formulations or tedious experimental methods requiring precise three-dimensional reconstructions of neuron arbors, tremendously branched structures formed by neurons.

Part of the difficulty in mapping lies in the complex structure of arbors. Amirikian has improved on past methods by developing a theoretical framework requiring only two-dimensional drawings of arbors. Such drawings are already available in the neuroscience literature for many types of neurons. With this method, neuron connection maps could be used to create computer simulations of neural circuits involving tens of thousands of neurons with biologically realistic connections--and provide a practical way to begin untangling the mysteries of the brain.


Citation: Amirikian B (2005) A phenomenological theory of spatially structured local synaptic connectivity. PLoS Comp Biol 1(1): e11.


Source:PLoS Biology

Page: 1

Related biology news :

1. Computational Method Speeds Mapping of Cell Signaling Networks
2. Mapping alcohol brain damage
3. Mapping the protein world
4. Mapping the mouse genome
5. New research questions basic tenet of neuron function
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. One gene links newborn neurons with those that die in diseases such as Alzheimers
8. Researchers make surprise discovery that some neurons can transmit three signals at once
9. Speak up: Louder neurons form more connections
10. Eating, body weight regulated by specific neurons
11. MIT researcher finds neuron growth in adult brain
Post Your Comments:

(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... Research and Markets has announced the addition of the ... ... to grow at a CAGR of 30.37% during the period 2017-2021. ... been prepared based on an in-depth market analysis with inputs from ... prospects over the coming years. The report also includes a discussion ...
(Date:4/6/2017)... LONDON , April 6, 2017 ... Control, RFID, ANPR, Document Readers, by End-Use (Transportation & ... Energy Facility, Oil, Gas & Fossil Generation Facility, Nuclear ... Healthcare, Educational, Other) Are you looking for ... Authentication sector? ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... 10, 2017 SomaGenics announced the receipt of ... develop RealSeq®-SC (Single Cell), expected to be the first ... (including microRNAs) from single cells using NGS methods. The ... to accelerate development of approaches to analyze the heterogeneity ... "New techniques for measuring levels of mRNAs in individual ...
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television series ... 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global population ... challenge of how to continue to feed a growing nation. At the same time, ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... advanced instruments and applications consulting for microscopy and surface analysis, Nanoscience Instruments ... consulting, Nanoscience Analytical offers a broad range of contract analysis services for ...
(Date:10/6/2017)... ... October 06, 2017 , ... On ... and webinar on INSIGhT, the first-ever adaptive clinical trial for glioblastoma (GBM). The ... The event is free and open to the public, but registration is required. ...
Breaking Biology Technology: