Navigation Links
Mapping neuron connections in the brain

The human brain contains from 10 to 100 billion neurons, and each has hundreds of connections with neighboring neurons. Making sense of these intricate connections is essential to understanding brain function, and the task is a monumental one.

Thanks to a new theoretical approach to mapping neuron connectivity published in PLoS Computational Biology by Bagrat Amirikian, a researcher at the Department of Neuroscience at the University of Minnesota, the task is now feasible. In the past, mapping connections between neurons was limited to either highly simplified formulations or tedious experimental methods requiring precise three-dimensional reconstructions of neuron arbors, tremendously branched structures formed by neurons.

Part of the difficulty in mapping lies in the complex structure of arbors. Amirikian has improved on past methods by developing a theoretical framework requiring only two-dimensional drawings of arbors. Such drawings are already available in the neuroscience literature for many types of neurons. With this method, neuron connection maps could be used to create computer simulations of neural circuits involving tens of thousands of neurons with biologically realistic connections--and provide a practical way to begin untangling the mysteries of the brain.

###

Citation: Amirikian B (2005) A phenomenological theory of spatially structured local synaptic connectivity. PLoS Comp Biol 1(1): e11.


'"/>

Source:PLoS Biology


Page: 1

Related biology news :

1. Computational Method Speeds Mapping of Cell Signaling Networks
2. Mapping alcohol brain damage
3. Mapping the protein world
4. Mapping the mouse genome
5. New research questions basic tenet of neuron function
6. First real-time view of developing neurons reveals surprises, say Stanford researchers
7. One gene links newborn neurons with those that die in diseases such as Alzheimers
8. Researchers make surprise discovery that some neurons can transmit three signals at once
9. Speak up: Louder neurons form more connections
10. Eating, body weight regulated by specific neurons
11. MIT researcher finds neuron growth in adult brain
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... RATON, Florida , March 31, 2016 ... LEGX ) ("LegacyXChange" or the "Company") ... for potential users of its soon to be launched ... video ( https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide ... the use of DNA technology to an industry that ...
(Date:3/29/2016)... 2016 LegacyXChange, Inc. (OTC: ... SelectaDNA/CSI Protect are pleased to announce our successful effort ... variety of writing instruments, ensuring athletes signatures against counterfeiting ... from athletes on LegacyXChange will be assured of ongoing ... Bill Bollander , CEO states, "By ...
(Date:3/22/2016)... India , March 22, 2016 /PRNewswire/ ... market research report "Electronic Sensors Market for Consumer ... Proximity, & Others), Application (Communication & IT, ... Geography - Global Forecast to 2022", published ... industry is expected to reach USD 26.76 ...
Breaking Biology News(10 mins):
(Date:5/19/2016)... May 19, 2016 ... (OTC PINK: RGBPP) announced today initiation of a ... cord blood based cancer immunotherapeutic product leveraging its ... Regen described a generation of cord blood derived ... gene silencing.  The product in development will be ...
(Date:5/18/2016)... ... , ... STACS DNA Inc., the sample tracking software company, today announced that ... processing to help them save time and reduce errors. , Sexual Assault kits are ... and victims informed of results. Due to a previous lack of tools, many forensic ...
(Date:5/17/2016)... ... May 17, 2016 , ... ... waste reduction applications, announced today it will be showcasing ManureMagicâ„¢ at booth V1061 ... was featured in the Wall Street Journal last year and more recently made ...
(Date:5/17/2016)... NC (PRWEB) , ... May 17, 2016 , ... A ... between kidney and bladder cancer and mesothelioma in families. Surviving Mesothelioma has just posted ... , Although people with a family member with bladder or kidney cancer seem to ...
Breaking Biology Technology: