Navigation Links
Mapping alcohol brain damage

UQ biochemists are working with American researchers to pinpoint why only some parts of the brain are damaged in alcoholics.

Associate Professor Peter Dodd and his team from UQ's School of Molecular and Microbial Sciences has secured a five-year, $1.23 million grant from the United States' biomedical funding arm, the National Institute of Health (NIH) to find out.

Chronic alcohol abuse kills brain cells in the front of the brain, which affect planning, and social interactions and inhibitions.

The UQ team with collaborators from The University of Texas, want to find out what makes these cells so vulnerable.

Professor Dodd said his team was analysing brain tissue from dead alcoholics, mostly Anglo-Celtic men who've averaged more than 10 drinks a day.

The group analyses samples using a microarray analysis, a process they pioneered with human brain samples in 2000.

From a DNA sample applied to a microscope slide, the microarray computer produces about 50,000 coloured spots showing which genes are expressed or switched on in the sample.

"What we're trying to find out is, what's different in the superior frontal cortex [front of brain] when you compare alcoholics with controls, that's not different in a spared area of the brain," Dr Dodd said.

"In that way we can start to find those messages that show altered expression in the area of the brain that shows the pathology."

He said the microarray analysis could be useful for many neurological diseases.

"It's got general applicability to neurological diseases, because most neurological diseases also exhibit regional selectivity of pathology."

Professor Dodd said researching proteins was the next step as that would tell them why some cells have impaired function.

He has also teamed up with United Kingdom colleagues to find out why people get addicted to alcohol -- with the long-term goal of producing a drug that could red
'"/>

Source:Research Australia


Page: 1 2

Related biology news :

1. Computational Method Speeds Mapping of Cell Signaling Networks
2. Mapping neuron connections in the brain
3. Mapping the protein world
4. Mapping the mouse genome
5. Controversial drug shown to act on brain protein to cut alcohol use
6. Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis
7. Investigating brain shrinkage in alcoholics
8. Russian surrogate alcohols are a killer
9. Looking for the genes that affect a persons level of response to alcohol
10. Genetic and environmental influences on alcohol consumption among rhesus monkeys
11. Both alcoholism and chronic smoking can damage the brains prefrontal cortex
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mapping alcohol brain damage

(Date:8/28/2014)... an expansion of marine protected areas is needed to ... According to investigators from the Wildlife Conservation Society and ... on saving the largest numbers of species, often at ... difficult-to-replace ecological functions. , Many vital ecological ... that also are food for millions of people. ...
(Date:8/28/2014)... to Research Careers) Program has announced the travel award ... October 18 22, 2014 in San Diego, California. ... of students, post doctorates and scientists from underrepresented groups ... to encourage the participation of young scientists at the ... conferred 16 awards totaling $29,600., The FASEB MARC Program ...
(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... Genetics Society of America,s 27th Annual Mouse Molecular ... 2014 in Pacific Grove, California. These awards ... post doctorates and scientists from underrepresented groups into ... to encourage the participation of young scientists at ...
Breaking Biology News(10 mins):Study finds marine protected areas inadequate for protecting fish and ocean ecology 2
... Washington D.C. (September 22, 2008): Integrating sophisticated ... information systems and clinical expertise has the ... lowering treatment costs. This is especially true ... today said an international panel of experts, ...
... to be involved in colon cancer but the exact mechanisms ... that a molecule produced by a common gut bacterium activates ... published in the October issue of the Journal of ... can cause colon cancer. There are more bacteria in ...
... energy doesn,t always mean solar or wind power. In ... chemical and biological engineering professor James Dumesic look a ... vehicles today. That,s because the new fuels are ... The only difference is where they come from. ...
Cached Biology News:Combining advanced medical and information technologies offers pathway to lower health care costs 2Combining advanced medical and information technologies offers pathway to lower health care costs 3Cancer-causing gut bacteria exposed 2New process derives 'green gasoline' from plant sugars 2
(Date:8/29/2014)... August 29, 2014 Local veterinarian, Dr. ... Hospital are seeking candidates to participate in an investigational ... The ultimate goal of this study is to ... into one or two arthritically affected joints can help ... , Candidates for the current investigational study must be ...
(Date:8/29/2014)... A major challenge before new biotechnology ... realm of Boston-Cambridge, is gaining visibility that can lead ... the Director of Boston’s Adult Stem Cell Technology Center, ... visibility of his company an important priority since he ... to a social media marketing campaign launched ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Best Sanitizers, ... for the food processing industry, is asking industry professionals ... side comparison of the E2 soap they’re currently using ... Foam Soap . Hand hygiene is critical to ... food processing environment. Six key criteria are identified to ...
(Date:8/28/2014)... WEST LAFAYETTE, Ind. A new research ... "nanomechanical" properties of tiny structures undergoing stress ... insights to improve designs for microelectronics and ... spectroscopy, reveals information about how heating and ... their mechanical properties. Researchers have discussed the ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3
... on its recent analysis of new products within the ... the 2012 North American Frost & Sullivan Award for ... a "gold standard" polymerase chain reaction (PCR) instrument. The ... amplification, and detection, all in a multiplexed, automated, and ...
... Inc. (NYSE Amex: BONE ), a leader in ... for medical applications, today announced its financial results for the ... Fourth Quarter 2011 Highlights: Revenue ... for the fourth quarter of 2010. Operating loss decreased ...
... March 21, 2012 When deciding between the ... the upcoming and existing research programs prove highly ... introduces the Life Sciences Content: Pharmaceuticals, Biotechnology, ... to 2012 compendium.  This resource includes Frost ...
Cached Biology Technology:Frost & Sullivan Recognizes iCubate for Developing the New Gold Standard Instrument in the PCR Market 2Frost & Sullivan Recognizes iCubate for Developing the New Gold Standard Instrument in the PCR Market 3Frost & Sullivan Recognizes iCubate for Developing the New Gold Standard Instrument in the PCR Market 4Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 2Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 3Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 4Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 5Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 6Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 7Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 8Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 9Bacterin Announces Record 2011 Revenue of $30.1 Million; Up 96% Year-over-Year 10Frost & Sullivan Announces Cutting Edge Life Sciences Research on the Horizon 2Frost & Sullivan Announces Cutting Edge Life Sciences Research on the Horizon 3
mu Opioid Receptor splice variant Immunogen: Synthetic peptide corresponding to residues K S C M D R G M R N L L P D D G P R Q E of Mu Opioid Receptor. Storage: -20 C, Avoid Freeze/Thaw Cycle...
Rac1/2/3 (L129) Antibody Shipping Temperature: HOT Storage Temperature: -20C...
In plasmid or lambda vector. Please inquire for more details!...
ANTI-RAT ADHESION MARKERS, CDs, CYTOKINES, ETC Rat ICAM PE - Mouse IgG1...
Biology Products: