Navigation Links
Mammalian Transcriptome Mapped

The FANTOM Consortium for Genome Exploration Research Group, a large international collection of scientists that includes researchers at The Scripps Research Institute's Florida campus, is reporting the results of a massive multi-year project to map the mammalian "transcriptome" in this week's issue of the journal Science.

The transcriptome, or transcriptional landscape as it is sometimes called, is the totality of RNA transcripts produced from DNA, by the cell in any tissue at any given time. It is a measure of how human genes are expressed in living cells, and its complete mapping gives scientists major insights into how our genome works.

"This is arguably the next major step after the human genome project," says Professor Claes Wahlestedt, M.D., Ph.D., who is the director of Pharmacogenomics at Scripps Florida. Wahlestedt is also a professor at the Karolinska Institute in Sweden, and is adjunct chief scientist at RIKEN Institutes, Japan. "Our Japanese collaborators, headed by Professor Yoshihide Hayashizaki, should be credited for their long-standing focus on generating novel data on the transcriptome," Wahlestedt continues.

The mammalian transcriptome has already revealed a number of new and startling things about the nature of mammalian biology. One of the most significant of these findings, about "antisense transcription," appears in a separate article by Wahlestedt and his colleagues in the same issue of Science.

Antisense transcription (see section below) was once thought to be rare, but the transcriptome reveals that it takes place to an extent that few could have imagined. "Instead of it being a rare phenomenon, we are showing that it is a massively abundant phenomenon," says Wahlestedt. "It is the rule rather than the exception."

This discovery has significant implications for the future of biological research, medicine, and biotechnology because antisense genes are likely to participate in the control of many, perha
'"/>

Source:Scripps Research Institute


Page: 1 2 3 4 5

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mammalian Transcriptome Mapped

(Date:3/26/2015)... The Granite Club, ... club, today announced it has implemented a state-of-the-art access ... for members and staff, while restricting access to authorized ... selected FST,s IMID Access system because it has the ... and staff, in addition to unparalleled security," said ...
(Date:3/23/2015)... Mass , March 23, 2015 SoundView Technology ... of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView was ... user feedback on their experience with the Wocket in multiple ... at CVS, Whole Foods and other retailers, making both debit ... Kris Tuttle also says, "If the company meets their ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has ... Strategic Business Report" report to their offering. ... US$ Thousands. The report provides separate comprehensive analytics for the ... , Europe , Asia-Pacific ... World. Annual estimates and forecasts are provided for ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... simulations, researchers at the University of Illinois have demonstrated a ... forth through a nanopore capacitor in a semiconductor chip. The ... genomes quickly and affordably., Being able to sequence a human ... insurance companies are willing to pay) could open a new ...
... BOWLING GREEN, O.Bowling Green State University biology undergraduates will ... genomics while they learn. The University has been selected ... new Microbial Genome Annotation research program through the U.S. ... Analysis of the genomes of microorganisms is an important ...
... Investigators at the University of Rochester Medical Center have ... of hope for children with Batten disease a ... robs them of their abilities to see, reason and ... The study, highlighted in the January edition of ...
Cached Biology News:New technique could dramatically lower costs of DNA sequencing 2BGSU undergraduates to pilot groundbreaking genome project 2BGSU undergraduates to pilot groundbreaking genome project 3Research unveils new hope for deadly childhood disease 2
(Date:4/16/2015)... (PRWEB) April 16, 2015 Capillus, ... distribution and physician network in Europe and Asia. ... has appointed Fernando Bermúdez, former Business Development Director ... An industry veteran, Mr. Bermúdez’s professional achievements include ... in Spain, while also penetrating the Portuguese marketplace ...
(Date:4/16/2015)... 16, 2015 OncoTAb, Inc., ... (UNC Charlotte) spin-out company, announced today the appointment ... M.D., as Chief Operating Officer (COO). Cooper brings ... in developing clinical diagnostic and biotechnology platforms in ... , Cooper’s extensive career transcends the field of ...
(Date:4/16/2015)... , April 16, 2015 /CNW/ - Bioenterprise Corporation is pleased ... office in Charlottetown , PEI.  Bioenterprise ... Edward Island ADAPT Council for the commercialization of agricultural ... to working with PEI ADAPT.  They have been at ... than a decade," explains Dave Smardon , President ...
(Date:4/16/2015)... SAN DIEGO , April 16, 2015 ... company dedicated to improving cancer surgeries, announced today that ... lead fluorescent cancer illuminator, AVB-620, in women with primary, ... trial, the company also welcomed the addition of ... affairs. The open label, dose escalation study ...
Breaking Biology Technology:Capillus, LLC Extends Laser Hair Therapy Products to Europe and Asia 2OncoTAb Names Dr. David L. Cooper as COO 2Bioenterprise Corporation Expands into the Maritimes 2Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 2Avelas Biosciences Initiates Phase 1b Trial of AVB-620 in Breast Cancer Patients 3
... Technologies, Inc.,(OTC Bulletin Board: AVXT) (the "Company") today ... bridge loan financing pursuant to a Convertible Note,and ... to Convertible,Note and Warrant Purchase Agreement (collectively the ... promissory notes,(the "Notes") in the aggregate principal amount ...
... SAN DIEGO, Oct. 30 Anadys Pharmaceuticals,Inc. (Nasdaq: ... ANA773 in,patients chronically infected with hepatitis C virus (HCV) ... ANA773 in both healthy volunteers and,HCV patients. ANA773 is ... of the study, patients in the first cohort will ...
... (Nasdaq:,CEPH) today announced that its Analyst Day in New ... be webcast live on the investor relations section of,its ... will review the company,s business,strategy, marketing plan and research ... November 5, 2008 beginning at,approximately 12:30 p.m. EST and ...
Cached Biology Technology:AVAX Technologies, Inc. Announces Closing of Bridge Loan Financing 2Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients 2Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients 3Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients 4Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients 5Cephalon, Inc. to Webcast Analyst Day 2Cephalon, Inc. to Webcast Analyst Day 3
IHC Detection Kit (Broad Spectrum AEC)....
...
...
... to L1 Cell Adhesion Molecule ... in Xq28, is involved in three distinct ... of Sylvius); 2) MASA (mental retardation, aphasia, ... (spastic paraplegia). Immunogen: ...
Biology Products: