Navigation Links
Malaria, potato famine pathogen share surprising trait

p of about 20 to 30 amino acids on a protein secreted by the parasite. This sequence contains instructions on how to enter, and therefore start infecting, a plant or animal cell.

In laboratory experiments, the researchers infected human red blood cells with the modified malarial pathogen.

Results showed that malaria proteins could just as effectively enter and infect a cell when it contained the P. infestans leader sequence instead of its own.

"Our findings show that very distinct microbes can share similar strategies for delivering toxic proteins to their targets," Kamoun said.

About a year and a half ago, Kamoun and his group at Ohio State read studies conducted by the Northwestern researchers that described the leader sequence of the malaria parasite. The similarity between this and the leader sequence of P. infestans was remarkable, he said.

"So we decided to collaborate and see if the sequences were not just similar, but also functionally the same," he said. "It turned out that they were. But although the mechanism of getting virulence proteins into a host cell is very similar, the infection-causing proteins that are delivered to a host are completely different."

To Kamoun's knowledge, this is the first paper to show that such dissimilar pathogens of this type - both are eukaryotic organisms ?share a remarkably similar trait. He and his colleagues aren't sure how to explain this phenomenon, as these pathogens belong to distinctly different evolutionary groups.


'"/>

Source:Ohio State University


Page: 1 2

Related biology news :

1. Researchers find gene that may be at root of potato blight
2. 15 generations of untrained jocks, couch potatoes show big physiological adaptations
3. Finding rewrites the evolutionary history of the origin of potatoes
4. Six million Africans face famine because of locusts, drought
5. Prenatal exposure to famine increases risk of schizophrenia
6. Researchers develop rapid diagnostic tool for pathogen identification
7. A new study examines how shared pathogens affect host populations
8. New lab technique identifies high levels of pathogens in therapy pool
9. Researchers uncover sequence of major rice pathogen
10. Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
11. Tagging pathogens with synthetic DNA barcodes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Malaria potato famine pathogen share surprising trait

(Date:12/10/2014)... CIE San Diego has launched an innovative ... tissue that enhances care coordination among social service and ... information; earned a second $1 million grant from the ... aging in community and; will be recognized as a ... 4-6p. CIE San Diego today announced ...
(Date:12/5/2014)... PROVO, Utah , Dec. 4, 2014  Tute ... has raised $2.3 million in Series A1 funding led ... angel investors also participated in the investment round. ... as the healthcare community adopts next-generation sequencing and seeks ... disease," said Reid Robison , MD MBA, and ...
(Date:11/21/2014)... According to a new market ... RFID, Access Control, Intrusion Detection, Parking Management, Under Vehicle ... Service Geography - Global Forecasts to 2020", published by ... be around $25 Billion in 2014 and is expected ... CAGR of 8.69%. Browse 116 market data ...
Breaking Biology News(10 mins):Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... LAFAYETTE, Ind. - Large hypoxic zones low in oxygen ... aquatic life, but a Purdue University study shows that ... not all species are impacted equally. Tomas Höök, ... former Purdue postdoctoral researcher Kristen Arend used output from ...
... the University of California, Riverside have found chemical evidence ... were oxygen-free and, surprisingly, contained abundant hydrogen sulfide in ... that ample hydrogen sulfide in the ocean was possible ... , a professor of biogeochemistry and the senior investigator ...
... within the brain,s neocortex lies a subnetwork of highly ... networks. Like Facebook, these neuronal networks have a small ... more information than the majority of other members, says ... Mellon and a member of the Center for the ...
Cached Biology News:Lake Erie hypoxic zone doesn't affect all fish the same, study finds 2Oxygen-free early oceans likely delayed rise of life on planet 2Oxygen-free early oceans likely delayed rise of life on planet 3Carnegie Mellon researchers identify 'Facebook neurons' 2Carnegie Mellon researchers identify 'Facebook neurons' 3
(Date:12/24/2014)... , Dec. 23, 2014 Sigma-Aldrich ... that the waiting period under the Hart-Scott-Rodino Antitrust ... acquisition expired on December 22, 2014, thereby completing ... requirement for the acquisition of the Company by ... antitrust clearance satisfies another condition to closing the ...
(Date:12/24/2014)... NEW YORK , Dec. 23, 2014 /PRNewswire/ ... study of mazindol in children with attention deficit/hyperactivity disorder ... December 2014 . The paper, titled ... attention deficit/hyperactivity disorder" ( Konofal et al, ... eCollection 2014 ) shows that mazindol might be ...
(Date:12/22/2014)... , Dec. 22, 2014   ... a developer of pathogen-specific therapies for serious ... protecting the microbiome, today announced positive topline ... 1a clinical trial of SYN-004, the Company,s ... of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... N.C. , Dec. 22, 2014  Alternative ... announced that it has signed a letter of ... that has developed and patented a nanotechnology-based development ... diagnostics products that enable rapid on-site collection and ... use/abuse and health issues in an immediate, non-invasive ...
Breaking Biology Technology:Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5ALNE Announces Intention To Acquire BioTechPharma 2
... (OTC Bulletin Board: PHST), a leading provider of ... drug,development, today announced that its Board of Directors ... Company,s stock, to take effect at 5:00,p.m., Eastern ... will,begin trading on a reverse split-adjusted basis under ...
... NEW YORK, Nov. 12 Informed Medical Communications,(IMC), ... service,companies, today named Charles T. Saldarini to its ... CEO, Steven K. Budd, from the company,s,headquarters in ... IMC an extensive history of entrepreneurial,innovation in the ...
... November 12 The Danish biotech cluster,known as ... into a global,hotspot in the field of personalized ... pharma and big biotech. Experience Danish,competencies at the ... 12th - 13th November. With over 10 ...
Cached Biology Technology:Pharsight Announces 1-For-3 Reverse Stock Split 2Pharsight Announces 1-For-3 Reverse Stock Split 3Informed Medical Communications Appoints Charles T. Saldarini to Board of Directors 2Danish Hotspot in Personalized Medicine 2
Human/Mouse/Rat JNK Pan Specific Affinity Purified PAb...
Request Info...
Cyan Standard is 7-hydroxy-4-trifluoromethylcoumarin...
Green Standard is fluorescein....
Biology Products: