Navigation Links
Major obesity gene is 'lost in the shuffle'

ed up and recombined with each other, erasing approximately 100 kilobases of DNA that spanned the ASIP gene."

Ranging in size from 15 to 22 pounds, gibbons possess lithe, slender bodies that enable them to swing agilely across branches and vines in the jungles. Ishida and Nakayama speculate that the loss of the ASIP gene in gibbons may have played a role in the evolution of the gibbons' uniquely slender body shape and size, although there is no biochemical or physiological evidence to suggest this.

"In essence, we are observing the result of an ancient gene 'knockout' experiment," Ishida explains. "The deletion ?or 'knockout' ?of the ASIP gene may have helped gibbons adapt to arboreal niches. We know that the ASIP protein regulates lipid metabolism in humans, so there is certainly reason to presume that this deletion contributed to the gibbons' remarkably small body mass, enabling them to thrive in the jungle canopy."

Ishida points out that future studies of gibbons and other primates will enable scientists to examine the physiological effects of the ASIP deletion. "This will allow us to identify the specific metabolic roles of ASIP in vivo by comparing a species that has the gene versus a species that lacks the gene," he says.


'"/>

Source:Cold Spring Harbor Laboratory


Page: 1 2

Related biology news :

1. Major new UNC-based drinking water study suggests pregnancy fears may be overstated
2. Major breakthrough in the treatment of cancers and infectious diseases
3. Major advance made on DNA structure
4. Major WHO study concludes calcium supplements can reduce complications during pregnancy
5. Major initiative proposed to address amphibian crisis
6. Major cancer study aims to identify protein markers for early-stage disease
7. Major link in brain-obesity puzzle found
8. Major gene study uncovers secrets of leukemia
9. Canadian youth 4th highest in international obesity study
10. Weight control protein may yield antiobesity drugs
11. Contagious obesity? Identifying the human adenoviruses that may make us fat
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Major obesity gene lost the shuffle

(Date:9/30/2014)... Mediterranean each year, but its deep-blue waters host ... 1,000 alien species, including fish, crustaceans, and algae ... activities. In the open-access journal Frontiers in ... analyzed data from a new information system developed ... introduction of alien species has changed the native ...
(Date:9/30/2014)... watermelon, salmon, and strawberries all have in common? ... of chromosomes and are diploid, these organisms are all ... chromosomesseedless watermelon and salmon have 3 and 4 sets ... this might seem surprising, in fact most plant species ... over a century ago, but only recently, with the ...
(Date:9/30/2014)... Prenatal exposure to tetrachloroethylene (PCE) in drinking water ... abruption, according to a new study led by ... , The study, published in the journal ... 1,019 unexposed pregnancies among 1,766 women in Cape ... late 1960s to the early 1980s by the ...
Breaking Biology News(10 mins):Biodiversity in the Mediterranean is threatened by alien species 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4Contaminated water linked to pregnancy complications, BU study finds 2
... an odd-looking mouse discovered through a U.S. government breeding program in ... set of ribs in its neck and nobody knew why. ... of California, San Francisco has now spilled the genetic secrets of ... new wrinkle in the genetic code an entirely unrecognized way ...
... to announce BIOLOGY OPEN (BiO), a new online only, ... of the biological sciences including cell science, developmental biology ... rapid publication for peer reviewed, scientifically sound observations and ... will address some big issues in publishing and is ...
... Two groups of small fish, one from a Caribbean island and ... fastest rates of evolution known in any organism, according to a ... found from Massachusetts to Venezuela -- and they are all pretty ... Davis graduate student working with Peter Wainwright, a professor of evolution ...
Cached Biology News:Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 2Mutant mouse reveals new wrinkle in genetic code, say UCSF scientists 3Announcing BIOLOGY OPEN from the Company of Biologists 2'Explosive' evolution in pupfish 2
(Date:10/1/2014)... METTLER TOLEDO’s newly improved XS balance ... balances as well as a dual range microbalance ... new SmartPan™ weighing pan delivers results up to twice ... balances, ergonomic design details mean users no longer need ... long periods in front of the balance. Barbara Bienlein, ...
(Date:10/1/2014)... CHICAGO , Oct. 1, 2014 ... purity Mannose (USP/NF, EP), manufactured in the ... conditions.  "Mannose has long been recognized for playing ... is a growing body of evidence that media ... and consistency of protein glycosylation," according to Dr. ...
(Date:10/1/2014)... September 30, 2014 New applications of ... that have evolved in nature over millennia are featured ... materials for applications in biophotonics in the October ... The journal is published by SPIE, the international society ... Several of the peer-reviewed articles are accessible via open ...
(Date:10/1/2014)... Sept. 30, 2014 This report ... in US$ Million by the following Product ... Enzymes. Specific end-use segments also analyzed are ... The report provides separate comprehensive analytics ... Middle East, and Latin America. Annual estimates ...
Breaking Biology Technology:METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 2METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 3Pfanstiehl Launches cGMP-produced Mannose for Cell Culture Media Optimization & Glycoprotein Biosynthesis 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 3Global Specialty Enzymes Industry 2Global Specialty Enzymes Industry 3Global Specialty Enzymes Industry 4Global Specialty Enzymes Industry 5Global Specialty Enzymes Industry 6Global Specialty Enzymes Industry 7Global Specialty Enzymes Industry 8Global Specialty Enzymes Industry 9Global Specialty Enzymes Industry 10Global Specialty Enzymes Industry 11Global Specialty Enzymes Industry 12Global Specialty Enzymes Industry 13Global Specialty Enzymes Industry 14Global Specialty Enzymes Industry 15Global Specialty Enzymes Industry 16Global Specialty Enzymes Industry 17Global Specialty Enzymes Industry 18Global Specialty Enzymes Industry 19Global Specialty Enzymes Industry 20Global Specialty Enzymes Industry 21Global Specialty Enzymes Industry 22Global Specialty Enzymes Industry 23Global Specialty Enzymes Industry 24Global Specialty Enzymes Industry 25Global Specialty Enzymes Industry 26
... Virent , a University of Wisconsin-Madison spinoff working ... from the Department of Energy for continued research. , ,The ... and sugar in a one-step process as part of a ... of the problems of storing hydrogen, a highly explosive gas. ...
... for the 21st Century Act, commonly called Check 21, ... electronic check imaging. , ,Check 21, which will come ... the efficiency of the payments system by legalizing the ... the physical documents. Using the substitute check, banks are ...
... live in interesting times. Not so long ago, we IT practitioners may ... moons on them. What we did was a mystery to the rest ... magic trick gone bad, there was a huge puff of smoke on ... for all the world to see. , ,Somewhere in all of that, ...
Cached Biology Technology:Wisconsin firms make acquisitions for Check 21 readiness 2IT leadership is not just for CIOs anymore 2
... workstation offers precise 96 and 384-well transfers ... 100ul and 200ul disposable tips, the 96 ... and precision across a volume range from ... two positions that enable indexing into 384 ...
... Rabbit Tissue Arrays contain 60 rabbit tissue samples ... contains 4 unstained slides and 1 hematoxylin and ... slide contains 15 different tissues from 4 rabbit ... per slide. Each tissue sample (or core) is ...
A univariate (peak height or area) quantitative multi-component analysis package....
... The new, upgraded micro 10 represents ... that brings many of the benefits of ... of the small benchtop dispenser. Dispensing accurate ... well, the micro 10 has unique advantages ...
Biology Products: