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Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer

ironmental Health in Northern Manhattan, and principal investigator on the research. “Having the tools to identify hepatocellular carcinoma at earlier stages, is truly a breakthrough for addressing the challenges that result from this highly lethal form of cancer.?

Dr. Santella and the team of researchers previously found that several environmental factors including aflatoxin B1, a dietary mold contaminant sometimes found in peanuts and corn; polycyclic aromatic hydrocarbons, ubiquitous environmental contaminants; and 4-aminobiphenyl, a carcinogen found in cigarette smoke, are also associated with the development of HCC. While HCC incidence is highest in East Asia and Sub-Saharan Africa, it is also increasing in the U.S primarily as a result of HCV infection.

“We are not only very excited about what this means in terms of early detection for hepatocellular cancer but optimistic about how it could also be applied to other cancers,?observes Dr. Santella.

The full study findings are published in the April 15, 2007 issue of Clinical Cancer Research.


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Source:Columbia University's Mailman School of Public Health


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