Navigation Links
Machine preservation may promote more organ sharing

Preserving the kidneys of deceased older donors on a pump ?as opposed to the conventional method of storing and transporting organs in a cooler ?may lower hospital costs, improve initial organ function, and promote greater use and more sharing of organs, according to new research by Wake Forest University Baptist Medical Center.

"By placing kidneys on a portable pump, preservation times can be safely extended to permit more time for sharing organs across the country," said Robert Stratta, M.D., lead researcher of the study, which is reported in the May issue of the Journal of the American College of Surgeons.

In addition, Stratta said, the pump can be used to project the kidney’s initial function ?allowing for more appropriate matching of donor organs and recipients.

While machine preservation, or pulsatile perfusion, is not new, it is not widely used because it is more costly and labor-intensive. According to the United Network for Organ Sharing, only 21 percent of kidneys from deceased donors are preserved on a pump.

The purpose of this study was to compare outcomes in kidney transplant patients receiving kidneys from older deceased donors based on whether organs were preserved by pump or cold storage.

"The critical organ shortage poses a challenge to optimize the use and function of all organs from deceased donors," said Stratta, explaining why it is important to compare the two methods of preservation.

With machine preservation, donated organs are connected to a portable pump to maintain a constant flow of a specialized preservation solution through the organs until transplantation. With both methods of preservation, a cooling solution is pumped into the organs during organ recovery. However, with simple cold storage, the kidneys are simply immersed in preservation solution and packed on ice until transplant.

The study involved organs from "expanded criteria" donors (ECDs). This category was cre
'"/>

Source:Wake Forest University Baptist Medical Center


Page: 1 2

Related biology news :

1. Machinery of the marijuana munchies
2. Slow-frozen people? Latest research supports possibility of cyropreservation
3. New technology addresses female fertility preservation
4. Whole genome promoter mapping - Human Genome Project v2.0?
5. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
6. Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors
7. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
8. Texas scientists discover how a hepatitis C protein promotes liver cancer
9. New antimicrobial compound adheres to skin to promote healing
10. A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
11. Free-radical busting antioxidants might not promote healthy hearts
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Machine preservation may promote more organ sharing

(Date:7/24/2014)... animal species for food or commercial food sale, has ... the decline of many species of primates and other ... than half of the species being consumed are birds, ... not only the meat made available for sale but ... by hunters and brought to villages for consumption, we ...
(Date:7/24/2014)... Imagine a smog-free Los Angeles, where electric cars ply ... run on heat from beneath the earth, from howling ... new Stanford study finds that it is technically and ... one powered by clean, renewable energy. Published in ... sustainable, inexpensive and reliable energy supply in California that ...
(Date:7/24/2014)... team of researchers has developed a new nanoscale agent ... method for assessing the function and properties of the ... diagnosis and treatment of gut diseases. , ... syndrome and inflammatory bowel disease all occur in the ... patients with diseases such as diabetes and Parkinson,s. ...
Breaking Biology News(10 mins):Stanford study shows how to power California with wind, water and sun 2Stanford study shows how to power California with wind, water and sun 3Stanford study shows how to power California with wind, water and sun 4New imaging agent provides better picture of the gut 2
... Advanced Computing Center (TACC) at the University of Texas ... support a world-class supercomputer with comprehensive computing and visualization ... possible by a $27.5 million grant from the National ... the NSF "eXtreme Digital" (XD) program, an integrating system ...
... immobilize and devour amphibian prey many times their size. Now ... of Zoology, has discovered that they have an additional advantage ... adult counterparts, have a unique method for luring and feeding ... sirens who lured Ulysses, sailors to their demise, larvae have ...
... genetic variant may explain why some people with asthma do ... medicine for long-term asthma control. Researchers found that asthma patients ... only one-third as well to steroid inhalers as those with ... association study, funded by the National Heart, Lung, and Blood ...
Cached Biology News:Stampede charges computational science forward in tackling complex societal challenges 2Stampede charges computational science forward in tackling complex societal challenges 3Stampede charges computational science forward in tackling complex societal challenges 4Amphibians: Beware young beetles' deadly 'siren call' 2NIH-funded study connects gene variant to response to asthma drugs 2
(Date:7/24/2014)... forces worldwide rely on sophisticated equipment, trained personnel, ... public areas against terrorist attacks. A revolutionary new ... to make their job much easier. , The ... of Tel Aviv University ,s School of Chemistry ... by the Herzliya company Tracense, picks up the ...
(Date:7/24/2014)... to settle into equilibriuma state of unchanging balance ... of non-equilibrium conditions where new possibilities lie. Non-equilibrium ... such as temperature fluctuations, freezing and melting, or ... body temperature, airplanes to fly, and the Earth ... even though these conditions exist naturally and are ...
(Date:7/24/2014)... , July 24, 2014 SRI International has ... the National Institute of Allergy and Infectious Diseases (NIAID), ... preclinical development of potential therapies for HIV infection and ... treat HIV and AIDS and the complications and opportunistic ... for preventing sexual transmission of HIV. ...
(Date:7/24/2014)... 24, 2014  Neogen Corporation (Nasdaq: NEOG ... its potential revenue from new rodenticide research are premature. ... analysts on July 22, 2014, Neogen,s CEO commented about ... research. "It was my intent Tuesday at ... of a new type of rodenticide, but certainly not ...
Breaking Biology Technology:Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3Neogen comments on SenesTech 2
... 2009 ... ... 2009 -- IntertechPira has teamed up with Carbonfund.org to create a zero-carbon event. ... those emissions to make the event carbon neutral by supporting energy efficiency, renewable energy ...
... , , SAN DIEGO, CA, July 30, ... second quarter 2009 financial results on Tuesday, August 4, 2009 before the ... conference call with a live Internet broadcast that will provide a corporate ... day at 11:00 a.m. Eastern Time (8:00 a.m. Pacific Time). , ...
... , , ALPHARETTA, Ga., ... recently announced the appointment of Philip Vogt as Executive Vice ... brings more than thirty years of pharmaceutical experience and ... Prior to this role, Vogt served as President of Ethex ...
Cached Biology Technology:Biopolymers Symposium 2009 Teams with Carbonfund.org to Create a Zero-Carbon Event 2SENOMYX, INC. SECOND QUARTER 2009 EARNINGS CONFERENCE CALL SCHEDULED FOR AUGUST 4, 2009 2
... loxP-PGK-gb2-neo-loxP template is designed to allow ... cells. The loxP-PGK-gb2-neo-loxP template encodes ... a prokaryotic promoter (gb2) for expression ... a eukaryotic promoter (PGK) for expression ...
... depletion cocktail is tailored to ... from suspensions of rat spleen ... the StemSep (or compatible 0.5 ... system. The CD4+ T cell ...
Standard Fluka For microscopy (Hist.) redox indicator...
... The VSOS-4 Orbital Shaker is designed ... to provide a uniform motion that is both ... The VSOS-4 Orbital Shaker provides a smooth, quiet, ... for a wide range of laboratory applications such ...
Biology Products: