( to develop noveland innovative genomic...)MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

to develop novel and innovative genomic research projects. "Moleculizer is exactly the sort of development that one wants to see from multidisciplinary work," explained Dr. Brent. "The mathematical and algorithmic skills that Dr. Lok brought to the problem could only come from one with his strengths, but the work is important because it addresses a problem arising directly from the biology." Dr. Daniel Gillespie, a pioneer in stochastic methods for modeling chemical kinetics stated, "Dr. Lok has succeeded in adapting and creatively extending earlier developed techniques for stochastically simulating chemical reactions so that they can be used to study real cellular systems, where the huge numbers of potential species and reaction channels makes things very difficult." Computer simulations can be powerful tools in contemporary molecular biology research, aiding scientists in analyzing data and in testing hypotheses with simulated outcomes before testing them experimentally. The predictive capabilities of computer simulations can also aid biologists in viewing cellular activity over a period of time, by taking advantage of the power of computers to generate the thousands of potential protein complexes and reactions that cells are able to generate. The Molecular Sciences Institute is an independent nonprofit research laboratory that combines genomic experimentation with computer modeling. Work at MSI aims to weave physics, engineering, computer science, and mathematics together with biology and chemistry to enable precise, quantitative, prediction of the future behaviors of biological systems. In keeping with the MSI's support for an open source biology, Moleculizer will be made freely available under the GNU Lesser General Public License. Nature Biotechnology is "a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences as
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Source:Eurekalert


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