Navigation Links
MIT's molecular sieve advances protein research

New MIT technology promises to speed up the accurate sorting of proteins, work that may ultimately aid in the detection and treatment of disease.

Separating proteins from complex biological fluids such as blood is becoming increasingly important for understanding diseases and developing new treatments. The molecular sieve developed by MIT engineers is more precise than conventional methods and has the potential to be much faster.

The team's results appear in recent issues of Physical Review Letters, the Virtual Journal of Biological Physical Research and the Virtual Journal of Nanoscale Science and Technology.

The key to the molecular sieve, which is made using microfabrication technology, is the uniform size of the nanopores through which proteins are separated from biological fluids. Millions of pores can be spread across a microchip the size of a thumbnail.

The sieve makes it possible to screen proteins by specific size and shape.In contrast, the current technique used for separating proteins, gel electrophoresis, is time-consuming and less predictable. Pore sizes in the gels vary, and the process itself is not well understood by scientists.

"No one has been able to measure the gel pore sizes accurately," said Jongyoon Han, the Karl Van Tassel Associate Professor of Electrical Engineering and Biological Engineering at MIT. "With our nanopore system, we control the pore size precisely, so we can control the sieving process of the protein molecules."

That, in turn, means proteins can be separated more efficiently, which should help scientists learn more about these crucial molecules, said Han, who also has appointments in MIT's Research Laboratory of Electronics, Computational and Systems Biology Initiative, Center for Materials Science and Engineering and Microsystems Technology Laboratories.

Han and his team, led by Jianping Fu, a graduate student in the Department of Mechanical Engineering, have devised a si
'"/>

Source:Massachusetts Institute of Technology


Page: 1 2 3

Related biology news :

1. MITs ocean model precisely mimics microbes life cycles
2. MITs ocean model captures diversity of underwater forests
3. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
4. Source of molecular triggers in cutaneous T cell lymphoma identified
5. Plants, animals share molecular growth mechanisms
6. NYU researchers simulate molecular biological clock
7. Scientists reveal molecular secrets of the malaria parasite
8. Scientists identify molecular events that drive cell senescence
9. Researchers discover molecular mechanism that desensitizes us to cold
10. Findings have implications for tracking disease, drugs at the molecular level
11. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: MIT molecular sieve advances protein research

(Date:9/2/2014)... Sam Kean stops by Reactions this week to debunk ... that, despite what "Shark Week" may lead you to ... http://youtu.be/KhFygIoW_MA . , Kean,s book, "The Disappearing Spoon: ... History of the World from the Periodic Table of ... 10-episode video series produced for the newly launched American ...
(Date:9/2/2014)... spiky legs and their propensity for eating anything, including ... And now research from North Carolina State University finds ... across the eastern United States. , "The good news ... kind of threat to humans," says Dr. Mary Jane ... author of a paper about the research. , The ...
(Date:9/2/2014)... N.C. -- When you accidentally touch a hot oven, ... the basic neural circuits involved in sensing and responding ... the molecular players. , Duke researchers have made a ... involved in pain in worms, and have built a ... 2 in Nature Communications , may help direct ...
Breaking Biology News(10 mins):Researchers find Asian camel crickets now common in US homes 2Surprising new role for calcium in sensing pain 2Surprising new role for calcium in sensing pain 3
... of Alzheimer,s disease reports improvement in language abilities ... the research, published today in the open access ... minutes of using this new treatment. Building ... in BioMed Central,s Journal of Neuroinflammation, ...
... to be the niche. As air and water preceded life, ... cells in many tissues and provides factors necessary to keep ... cell dependents. A team of scientists at the ... assistant professor in the Laboratory of Genetics, now suggests that ...
... the burgeoning field of interventional therapies for congenital ... Vegas July 20-23 for the Pediatric & Adult ... Medical Center in Chicago will perform live cases ... On Monday, July 21st, Dr. Ziyad M. ...
Cached Biology News:Stem cell chicken and egg debate moves to unlikely arena: the testes 2Stem cell chicken and egg debate moves to unlikely arena: the testes 3Latest advances in interventional cardiology for congenital heart disease presented 2
(Date:9/2/2014)... Massachusetts , September 2, 2014 ... to BioData,s research and lab management services  ... management service, is pleased to announce the appointment of ... Culot most recently served as VP Marketing and Business ... life science research and clinical applications. Previously, ...
(Date:9/1/2014)... 01, 2014 The Collaborative R&D ... report provides comprehensive understanding and unprecedented access to ... by the worlds leading life science companies. , ... of how and why companies enter collaborative R&D ... partner’s negotiated deals terms provides critical insight into ...
(Date:8/31/2014)... Dallas, Texas (PRWEB) August 31, 2014 ... on the current state of the Epoxy Hardener ... provides a basic overview of the industry, including ... analysis and Chinese domestic market analysis are provided ... competitive landscape of the market. A comparison between ...
(Date:8/29/2014)... Albany, New York (PRWEB) August 29, 2014 ... be valued at $5.6 billion in 2019. It ... 18.1% from 2013 to 2019, and was valued ... research report published by Transparency Market Research. , ... please visit: http://www.transparencymarketresearch.com/companion-diagnostics-market.html . , The research ...
Breaking Biology Technology:Louis Culot Appointed as BioData's CEO 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 2Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 3Collaborative R&D Terms & Agreements in Pharma, Biotech and Diagnostics Industry Analysis, Size, Share, Growth, Trends And Forecast Research Report by Researchmoz.us 4Epoxy Hardener Industry Development Trends in Global & China Regions Now Available at ReportsnReports.com 2Epoxy Hardener Industry Development Trends in Global & China Regions Now Available at ReportsnReports.com 3Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3
... Medarex, Inc. (Nasdaq: MEDX ) is ... at 8:30 a.m. Eastern Time on Thursday, April 30, ... for the first quarter of 2009.To access the call ... webcast can be accessed through the Investor Relations section ...
... Integrity Provider First to Bring IP Ownership into Discussion , ... ... LLC , the leading provider of data integrity solutions, announced today ... and only data integrity protection provider of its kind ...
... BioMS Medical Corp (TSX: MS), a leading developer in the ... Giese, President and CEO, will present at a session entitled ... technology sector" as part of the Alberta Economic Forum in ... Monday May 4th at 10:05am (Local time), ...
Cached Biology Technology:Medarex to Host Business and Financial Update Conference Call on Thursday, April 30, 2009 2Surety, LLC Joins Microsoft BioIT Alliance 2Surety, LLC Joins Microsoft BioIT Alliance 3BioMS Medical to present at Alberta Economic Forum in Geneva 2
MAb to Transferrin Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business Days...
Rabbit polyclonal to IRS1 (phospho S636) ( Abpromise for all tested applications). entrezGeneID: 3667 SwissProtID: P35568...
Leucine-rich repeat-containing G-protein coupled receptor 4...
Rabbit polyclonal to MDM2 (phospho S185) ( Abpromise for all tested applications). entrezGeneID: 4193 SwissProtID: Q00987...
Biology Products: