Navigation Links
MIT device draws cells close -- but not too close -- together

On a popular children's game participants stand as close as possible without touching. But on a microscopic level, coaxing cells to be very, very close without actually touching one another has been among the most frustrating challenges for cell biologists.

Now MIT researchers led by Sangeeta Bhatia, associate professor of electrical engineering and computer science at the Harvard-MIT Division of Health Sciences and Technology (HST) and Brigham and Women's Hospital, have solved the problem with a novel device. The work promises to allow researchers to perform cellular experiments that were previously impossible.

Bhatia and HST postdoctoral associate Elliot Hui describe the device in the March 27 online issue of the Proceedings of the National Academy of Sciences. Hui is first author of the paper.

The new device, a microelectromechanical system (MEMS), allows biologists to physically arrange cells to be either touching, close but not touching, or completely separated from one another. Further, they can change that configuration at will. And the device works without the use of tools such as the microscopes or robotic control arms typically required by MEMS devices.

Because cells communicate via signals transmitted both through the touching of cell membranes and through soluble molecules that flow between separated cells, biologists need to vary the spacing of cells to study their interactions. Also, since some signals induce a cell to change its internal programming, it is important for biologists to be able to rearrange cells over time to learn which signals spur change and which don't.

In the past, researchers erected chemical "moats" around cells in an attempt to keep them close but separate. Over time, however, cells invariably breech the divide. "They are very good at crossing the moat," said Bhatia, who performed several such experiments in graduate school.

Bhatia and Hui's first thoughts about how to so
'"/>

Source:Massachusetts Institute of Technology


Page: 1 2 3

Related biology news :

1. Columbia study shows widely used artery clearing device does not help patients during heart attack
2. New defibrillator signals doctor of patients irregular heartbeat or device malfunction
3. Breakthrough in micro-device fabrication combines biology and synthetic chemistry
4. Carnegie Mellon scientists create PNA molecule with potential to build nanodevices
5. Researchers make long DNA wires for future medical and electronic devices
6. 3D ultrasound device poised to advance minimally invasive surgery
7. FDA approves first medical device using rutgers biomaterial
8. Underwater listening devices yield discoveries about endangered large whales
9. New device could cut chemotherapy deaths
10. Professors to develop hand-held pathogen testing device
11. Worlds smallest cancer detection device
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: MIT device draws cells close but not too close together

(Date:7/9/2014)... bladders of healthy women differ from bacteria in ... to researchers from Loyola University Chicago Stritch School ... 9, 2014, in the American Society for Microbiology,s ... communities may play a role in female urinary ... common, yet poorly understood, condition with symptoms similar ...
(Date:7/9/2014)... Centre (CNIO) have discovered that NANOG, an essential gene ... stratified epitheliathose that form part of the epidermis of ... adult organisms. According to the conclusions of the study, ... factor could also play a role in the formation ... and skin. , The pluripotency factor NANOG is active ...
(Date:7/9/2014)... studying critically ill children with traumatic injuries have ... are likely to develop a hospital-acquired infection. The ... and published online in June in the journal ... efforts that could lead to the clinical implementation ... prevent or reverse immune system damage following critical ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Immune function predicts infection risk among child trauma patients 2Immune function predicts infection risk among child trauma patients 3
... Dana-Farber Cancer Institute (Dana-Farber), Burnham Institute for Medical ... and Prevention (CDC) have reported the identification of ... range of influenza A viruses, including avian influenza ... some seasonal influenza viruses. These antibodies have the ...
... International, Inc. (OTC Bulletin Board: BKYI), a leader in ... today that it will participate in Imperial Capital,s Homeland ... of March. Additional details regarding BIO-key,s participation at ... , Imperial Capital,s ...
... Permanently Disposes Magnetically Recorded Data to Help QSGI,s ... Calif., Feb. 18 Fujitsu Computer Products of ... products including hard disk drives, peripherals and biometric ... using the Fujitsu Mag EraSURE degaussing ...
Cached Biology News:Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses 2Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses 3BIO-key(R) Announces Conference Schedule 2QSGI Integrates Fujitsu Mag EraSURE Data Degausser into its Suite of Information Technology Security Services 2QSGI Integrates Fujitsu Mag EraSURE Data Degausser into its Suite of Information Technology Security Services 3QSGI Integrates Fujitsu Mag EraSURE Data Degausser into its Suite of Information Technology Security Services 4QSGI Integrates Fujitsu Mag EraSURE Data Degausser into its Suite of Information Technology Security Services 5
(Date:1/14/2014)... DC (PRWEB) January 14, 2014 Carahsoft ... for Thursday, January 23, 2014 at 2pm EST (11am ... Knowledge.” The topic focuses on how technology can turn ... critical decisions for government agencies. The online webinar will ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
(Date:1/14/2014)... Global Record Systems, LLC, (GRS), ... solutions for patients, physicians, the biopharmaceutical industry, regulators, ... the signing of a three-year Research Collaboration Agreement ... (FDA). This initiative is designed to generate ...
(Date:1/14/2014)... 14, 2014 Independent publisher Bitingduck Press, ... Montreal, Canada, has big ideas for 2014 in production ... goals are to produce high-quality, low-cost, DRM-free ebooks and ... businesses. , The first major development will be ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... Caffeine Test Strips, to Know for Sure, Studies show that ... ... levels of caffeine, MONROVIA, Calif., Nov. 12 Ever wonder whether ... for sure,with new D+CAF, the first ever do-it-yourself caffeine test strip from,Silver ...
... MaxCyte, Inc.,the pioneer in scalable, high performance ... a live discussion with industry experts on the,challenges ... discussion is open to the industry and will ... 2:00-3:00EST., One of the respected industry experts ...
... Implementation Issues and Recommendations, BETHLEHEM, Pa., ... of Clinical Value Marketing, Infusion Systems Division ... Services for B. Braun Medical,Inc. (B. Braun), ... and services,recently represented B. Braun at the ...
Cached Biology Technology:Is Your Decaf Really Decaf? 2MaxCyte Hosts Live Discussion with Industry Experts on the Challenges in Developing Cell-Based Screening Assays for Drug Discovery 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 3
... The dsRNA Marker consists of ten ... 200, 300, 400, 500 and 1,000 base ... size marker for determinating sizes of double-stranded ... in the dsRNA Marker is adjusted to ...
... size markers are a mixture of Strep•Tag® ... 100 kDa. The markers provide precise size ... staining with Coomassie blue. Because each of ... the markers can also be detected by ...
Mouse monoclonal antibody to ACP2 - acid phosphatase 2, lysosomal...
... V, is used for agitation and mixing applications ... and destaining of gels and blots, and Southern ... rpm) and can handle a maximum load of ... 29 x 21 cm platforms covered with nonslip ...
Biology Products: