Navigation Links
MBL leads effort to update E. coli genome

E.coli is one of the most important model organisms for molecular science today and is arguably the single organism about which the most is known. The genes of higher-level plants and animals, even humans, are often understood by their similarity to E. coli genes. As such, the accuracy and completeness of E.coli genome information is of great importance to the scientific community.

In an attempt to consolidate the efforts of scientists working independently on the genome of the E.coli K-12 strain, an international team of biologists, led by MBL (Marine Biological Laboratory) scientists Monica Riley and Margrethe "Gretta" Serres, has published a comprehensive, updated description of all 4,500 E. coli K-12 genes. The data is presented in the January 5, 2006 online issue of the journal Nucleic Acids Research.

"The E. coli scientific community is scattered," said Riley, a senior scientist in the MBL's Josephine Bay Paul Center for Comparative Molecular Biology and Evolution. "We determined that we needed to get together and pool everything we know into one package. E. coli is one of the most important model organisms for molecular science today. Our work will help move this forward."

A group of 19 scientists from four countries updated the annotation of E. coli K-12 at two MBL workshops organized by Riley and Serres. Annotation involves identification of genes, and their starting and ending sites, as well as the description of gene products. The process helps scientists to determine gene function.

During the MBL workshops, Riley and her colleagues assigned known or predicted gene functions to each E. coli K-12 product based on previously known experimental evidence or sequence analysis. "We cooperated to an amazing extent, reviewing every single one of 4,500 genes of E. coli K-12," said Riley. The scientists developed the best consensus on the status and properties of each of the E.coli K-12 genes at the present moment. Their goal
'"/>

Source:Marine Biological Laboratory


Page: 1 2

Related biology news :

1. Study of genomic DNA leads to new advances in cancer diagnostics
2. Combination therapy leads to partial recovery from spinal cord injury in rats
3. Chemical guidance of T cells leads to immunologic memory and long-term immunity
4. Basic research leads to a novel cancer therapy
5. Less antibiotic use in food animals leads to less drug resistance in people, study shows
6. With cochlear implants, earlier use leads to better speech
7. Pest control research leads to pain control discovery
8. UT Southwestern researchers find gene mutation that leads to broken hearts
9. Nicotine exposure during development leads to hearing problems
10. Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection
11. Dopamine drug leads to new neurons and recovery of function in rat model of Parkinsons
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: MBL leads effort update coli genome

(Date:9/18/2014)... probably the ultimate form of camouflage: you don,t just ... strategy is not as uncommon as you might think. ... USA, explains that the larval life stages of many ... of the anatomy that most creatures cannot make transparent. ... to shield each individual eye unit with an opaque ...
(Date:9/17/2014)... From accessible and affordable health care to reproductive ... depend on the ability of people to identify ... openly and respectfully, and find the most defensible ... practices to support these societal conversations?, The Hastings ... of Bioethical Issues have teamed up to publish ...
(Date:9/17/2014)... student have designed a device based on a shorebird,s ... dew., The device could provide water in drought-stricken areas ... Luo, professor in the Mechanical & Aerospace Engineering Department, ... of Engineering department, published "Bioinspired Plate-Based Fog Collectors" in ... Applied Materials & Interfaces journal. ...
Breaking Biology News(10 mins):Transparent larvae hide opaque eyes behind reflections 2Why bioethics literacy matters 2Why bioethics literacy matters 3Shorebird's beak inspires UT Arlington research on water collection 2
... - Eurofins MWG Operon, an expert in next generation sequencing ... libraries for sequencing with Roche GS FLX or Illumina HiSeq ... long paired end (LPE) libraries with different jumping distances (3 ... After sequencing, the resulting reads are assembled into large contigs ...
... of a TB Vaccine PDP, An Exhibitor,s Workshop at the ... 1:00-2:00 PM VENUE: 2011 AAAS ANNUAL MEETING, ,WASHINGTON CONVENTION ... an overview of the state of the global TB epidemic ... product development partnerships such as Aeras; and ways that scientists ...
... found attached to the foot of an ancient Egyptian mummy ... parts, says the scientist who tested replicas on volunteers. ... a three-part wood and leather artefact housed in the Egyptian ... Chester artificial toe on display in the British Museum, not ...
Cached Biology News:Mummies' false toes helped ancient Egyptians walk 2
(Date:9/18/2014)... Pipette.com announces brand new ... and AccuPet brand of pipettes. Micropipettes are ideal ... less and are a great tool for molecular ... The micropipette promotions were designed to offer a ... to help customers find the right solution. Brands ...
(Date:9/17/2014)... A long-term retrospective study of breast ... via interstitial brachytherapy suggests that women younger than ... be suitable to receive the treatment. Current American ... patients in the "unsuitable" category for APBI. In ... Beaumont Health System,s Peter Y. Chen , ...
(Date:9/17/2014)... and PRINCETON, N.J. , ... OTCQB:AEMD), the pioneer in developing targeted therapeutic devices to ... its diagnostic subsidiary, Exosome Sciences, Inc. (ESI), disclosed today ... Exosomes & SingleCell Analysis Summit. On September ... Sciences will give a presentation entitled: "Exosomes: A Multiplexed ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 JH ... California showroom located in Irvine. JH Technologies, a ... imaging systems, recently announced an expanded partnership with Leica ... leading microscopes and image analysis solutions will be featured ... 2nd. The new showroom facility is located within ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces Promotions on Sartorius/Biohit, Socorex, Capp, and AccuPet Micropipettes 2Major Pipette Distributor Pipette.com Announces Promotions on Sartorius/Biohit, Socorex, Capp, and AccuPet Micropipettes 3Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 2Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 3Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 4Aethlon Medical and Exosome Sciences To Present at the Exosomes & SingleCell Analysis Summit 2Aethlon Medical and Exosome Sciences To Present at the Exosomes & SingleCell Analysis Summit 3JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 3
... SAN DIEGO, Dec. 13 Neurocrine Biosciences,Inc. (Nasdaq: ... at its San Diego campus, as a part of ... and associated costs,and expenses after the setback on indiplon. ... "It is with great disappointment that we have to ...
... with drug-eluting,stents must take a combination of aspirin ... year, and possibly longer, after stent,implantation. This is ... today in the journals of the Society for ... (ACC), and,American Heart Association (AHA). To access the ...
... /Xinhua-PRNewswire/ -- Sinovac Biotech Ltd. (Amex:,SVA), a leading ... it has,notified the Listing Qualifications Department at the ... 2007 annual stockholders meeting,to no later than April ... 2007 annual stockholders meeting,in August 2007. The meeting ...
Cached Biology Technology:Neurocrine Announces Work Force Restructuring 2Neurocrine Announces Work Force Restructuring 3PCI Guideline Update Stresses Long-Term Anticoagulant Therapy After Treatment With Drug-Eluting Stents 2PCI Guideline Update Stresses Long-Term Anticoagulant Therapy After Treatment With Drug-Eluting Stents 3PCI Guideline Update Stresses Long-Term Anticoagulant Therapy After Treatment With Drug-Eluting Stents 4Sinovac Requests Extension for Annual Shareholders Meeting 2
Mouse Anti-Human Methyl-CpG binding domain protein 2 (MBD2 Monoclonal Antibody Family: Other Applications: Western Blot...
... Shaker combines shaking and rocking for maximal fluid ... 330 mm stainless steel or acrylic platform, it ... room operation. The platform angle is easily adjusted ... with action and rotation speed of platform is ...
...
Monoclonal Anti-Cystatin A tissue culture supernatant Solution containing 15 mM sodium azide human cystatin A ...
Biology Products: