Navigation Links
Living taste cells produced outside the body

onths, were similar to mature taste cells in several key respects. A variety of methods were used to show that the cultured cells contain unique marker proteins characteristic of mature functioning taste receptor cells. In addition, functional assays revealed that the cultured cells responded to either bitter or sweet taste stimuli with increases of intracellular calcium, another property characteristic of mature taste cells.

Lead author Hakan Ozdener, MD, PhD, observes, "Although scientists have tried for many years to maintain taste cells in a long-term culture system, it was commonly believed that these cells could not be kept alive for longer than about 10 days. Now, we have demonstrated that taste cells can be generated in vitro and maintained for a prolonged period of time."

The taste cell culture system provides new insight into how basal cells turn into functional taste cells. Although previous dogma had held that induction was somehow dependent on interactions with the nervous system, the current findings suggest otherwise. Ozdener explains, "By producing new taste cells in an in vitro system, our results demonstrate that direct stimulation from nerves is not necessary to generate taste cells from precursors."

By using the cultured taste cells, researchers now have more precise control over the cell's surrounding environment, as well as better access to subcellular mechanisms, allowing them to ask certain questions that could not previously be addressed.

For instance, cultured cells can be used to study how taste stimuli interact to enhance good tastes or suppress unpleasant tastes. Similarly, new molecules, including potential artificial sweeteners or bitter blockers, can be evaluated to see if they interact with taste receptors to activate the cell.

Another important avenue for research aims to help people who have lost their sense of taste from radiation or diseases. Identification of factors that promote tast
'"/>

Source:Monell Chemical Senses Center


Page: 1 2 3

Related biology news :

1. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
2. Living with salt
3. Living anti-HIV gel shows early promise
4. Living laboratory found on shoreline statues
5. Study: Living coral reefs provide better protection from tsunami waves
6. Living view in animals shows how cells decide to make proteins
7. Living with water scarcity -- world must act now
8. Childrens taste sensitivity and food choices influenced by taste gene
9. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
10. Bad aftertaste? New sensory on/off switch may cure bane of artificial sweetener search
11. Bitter or sweet? The same taste bud can tell the difference
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Living taste cells produced outside the body

(Date:4/14/2015)... 2015  HYPR Corp. today announced it has ... Alliance tm , an industry consortium transforming online ... share technology and collaborate to deliver open specifications ... secure and private, and easier to use. ... protects sensitive user information and eliminates the dependency ...
(Date:4/13/2015)... According to a recently ... & Opportunities, 2020", the global biometrics market is ... till 2020. The biometrics market is garnering attention ... review of biometric management systems. The constant development ... greater efficiency, are resulting in increasing installation of ...
(Date:4/10/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/cjk4gb/security ) ... Profiles - NEC" report to their offering. ... continue to supply a range of IT security management ... focus on the development of a Big Data and ... the Asia-Pacific region is a ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NEC Security Competitive Profile 2015 2
... screening the genome of hundreds of thousands of individuals ... more than 100 regions in the genome to the ... Molecular Biology Laboratory (EMBL) and the University of Heidelberg, ... taking these results one step further by pinpointing the ...
... 2013) "Green" chemistry developed at Rice University is at ... waste into fatty acids, and then into fuel. The ... recently announced $25 million United States Department of Agriculture project ... products from switchgrass and forestry residues and from a new ...
... have been a source of great controversyparticularly in Europebut ... scientific evidence about the health and ecological impacts of ... field site dedicated for use in GM crop studies ... interested in pursuing crop biotechnology, according to an article ...
Cached Biology News:Zeroing in on heart disease 2Modified bacteria turn waste into fat for fuel 2Modified bacteria turn waste into fat for fuel 3Fighting GM crop vandalism with a government-protected research site 2
(Date:4/24/2015)... 2015 DryLet, LLC a biotechnology ... such as animal waste reduction, bioremediation, wastewater treatment, ... wastewater treatment plants and restaurant kitchen settings, announced ... National Restaurant Association’s NRA Show 2015, in Chicago, ... the company will be available to share information ...
(Date:4/24/2015)... April 24, 2015 /CNW Telbec/ - Mirego, leader in mobile ... making of three mobile app extensions for the all new ... its clients, Familiprix, OMSignal and MediaMiser, these extensions will reinvent ... functions designed specifically for wrist use.  Available ... is a highly customizable tactile smartwatch that makes for an ...
(Date:4/24/2015)... Seoul Semiconductor announced the expansion of ... the lighting market. In recent months, there ... in emerging markets such as Russia, South America, ... applications such as streetlight and area lighting, tunnel ... launched in 2005 the Acrich technology from Seoul ...
(Date:4/23/2015)... Dora, Florida (PRWEB) April 23, 2015 ... that it intends to conduct a groundbreaking pilot ... begin to be reversed in as little as ... the science of metabolic and nutritional medicine—will aggressively ... that cripple and destroy our aging brain. These ...
Breaking Biology Technology:DryLet to Showcase Bio-React at the National Restaurant Association’s NRA Show 2015 May 16-19, 2015 in Chicago, Illinois 2Familiprix, OMSignal and MediaMiser apps available today for Apple Watch 2Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2New Study Looks to Reverse Alzheimer’s Disease 2New Study Looks to Reverse Alzheimer’s Disease 3
... Hu of China - Source: Getty Images The Olympics ... four years. They're held every year. Though this is still ... as the pervasive growth of the industry becomes part of ... every four years and last two weeks, the biotech Olympics ...
... MADISON, Wis. - Ownership and accountability is the way ... 448-bed community hospital in Madison that provides medical care ... living facility, laboratories and a home health care service. ... Methodist Hospital in 1987, Meriter includes more than 430 ...
... trend three years ago many companies cut their information ... the price of computers dropped, allowing businesses to inexpensively ... grew. Many IT staffers are wary of returning to ... looked to begin working as an outside IT source, ...
Cached Biology Technology:The Olympics: A Biotech Perspective 2The Olympics: A Biotech Perspective 3Meriter IT team builds project performance through internal relationships 2Meriter IT team builds project performance through internal relationships 3Meriter IT team builds project performance through internal relationships 4Expetec expands IT staff services in Wisconsin 2Expetec expands IT staff services in Wisconsin 3
Rabbit polyclonal to GABA A Receptor gamma 2 ( Abpromise for all tested applications). entrezGeneID: 2566 SwissProtID: P18507...
Rabbit polyclonal to VPAC2 ( Abpromise for all tested applications). entrezGeneID: 7434 SwissProtID: P41587...
Anti-GOSR2 Monoclonal AntibodyOther Sub-Family: not assigned-Other Applications: Immunocytochemistry, Immunoprecipitation, Western Blot...
Mouse monoclonal [4A2.2] to SLC6A4 ( Abpromise for all tested applications). entrezGeneID: 6532 SwissProtID: P31645...
Biology Products: