Navigation Links
Living taste cells produced outside the body

Researchers from the Monell Chemical Senses Center have succeeded in growing mature taste receptor cells outside the body and for the first time have been able to successfully keep the cells alive for a prolonged period of time. The establishment of a viable long-term model opens a range of new opportunities to increase scientists' understanding of the sense of taste and how it functions in nutrition, health and disease.

"We have an important new tool to help discover molecules that can enhance or block different kinds of tastes," explains principle investigator Nancy Rawson, PhD, a cellular biologist. "In addition, the success of this technique may provide hope for people who have lost their sense of taste due to radiation therapy or tissue damage, who typically lose weight and become malnourished. This system gives us a way to test for drugs that can promote recovery."

The findings are reported in an online issue of Chemical Senses.

Taste receptor cells are located in taste buds on the tongue and in the throat. These cells contain the receptors that detect taste stimuli: sweet, sour, salty, bitter, and umami (savory). Each taste receptor cell lives for only about 10-14 days, after which it is replaced. The new taste cells develop from a population of undifferentiated precursors known as basal cells.

Understanding of the process of taste cell differentiation, growth and turnover has been hampered by the inability of researchers to keep taste cells alive outside the body in controlled laboratory conditions.

To address this long-standing problem, the Monell researchers utilized a novel approach. Instead of starting with mature taste cells, they obtained basal cells from rat taste buds and placed these cells in a tissue culture system containing nutrients and growth factors. In this environment, the basal cells divided and differentiated into functional taste cells.

The new cells, which were kept alive for up to two m
'"/>

Source:Monell Chemical Senses Center


Page: 1 2 3

Related biology news :

1. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
2. Living with salt
3. Living anti-HIV gel shows early promise
4. Living laboratory found on shoreline statues
5. Study: Living coral reefs provide better protection from tsunami waves
6. Living view in animals shows how cells decide to make proteins
7. Living with water scarcity -- world must act now
8. Childrens taste sensitivity and food choices influenced by taste gene
9. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
10. Bad aftertaste? New sensory on/off switch may cure bane of artificial sweetener search
11. Bitter or sweet? The same taste bud can tell the difference
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Living taste cells produced outside the body

(Date:8/10/2015)... August 10, 2015 The latest 364 ... comprehensive analysis of the global border security market . ... of $16.4bn in 2015. Now: Border security is ... example of the business critical issue you need to know ... visiongain ,s objective analysis of how this will impact your ...
(Date:8/5/2015)... 5, 2015 Transparency Market Research ... Market - Global Industry Analysis, Size, Share, Growth, Trends ... facial recognition is forecast to reach US$ 2,671.8 Mn ... for surveillance systems by civil and government agencies. This ... and terrorist activities across the globe that would elevate ...
(Date:7/31/2015)... juli 2015 Den 10. internationale konference om ... den 22. - 25. oktober i Shenzhen ... 10-års fødselsdag i år. Siden starten i 2006 er ... på ,omik,-feltet, og er en af de mest dynamiske, ... fokuserer på nylige gennembrud og fremskridt inden for ,omik,-forskning, ...
Breaking Biology News(10 mins):Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2
... which finally proves that bones found in Shropshire, England ... in North Western Europe publishes today in the ... the surrounding environment suggests that some mammoths remained part ... to have become extinct. The mammoth bones, consisting ...
... dinosaur in China. The finding, they say, demonstrates that ... the Jurassic period than previously thought, and offers important ... from the hand of dinosaurs. The discovery is ... of the journal Nature . "This work ...
... of researchers, which includes scientists at the Virginia Bioinformatics ... sequence of Azotobacter vinelandii , uncovering important genetic ... of the biology of this versatile, soil-living bacterium. The ... ,s role as a model study organism for investigation ...
Cached Biology News:New discovery suggests mammoths survived in Britain until 14,000 years ago 2Beaked, bird-like dinosaur tells story of finger evolution 2Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii 2Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii 3
(Date:9/1/2015)... (PRWEB) , ... September 01, ... ... the launch of the new ImageXpress® Micro Confocal High-Content Imaging System. This ... emerging assays that use 3D cellular models such as spheroids, tissues, and ...
(Date:9/1/2015)... ... September 01, 2015 , ... Leading CEOs, ... and pain management space join prominent academics and key investors for Neuro Advance ... Medical School in Boston. , Neuro Advance Boston focuses on the latest ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... colleagues from University of California Los Angeles, Boston University School of Medicine, Frederick ... appears in PLOS One, the world’s first multidisciplinary Open Access journal. , ...
(Date:8/31/2015)... ... 2015 , ... In recent years, biodegradable plastics have found ... footprints and compostability. These properties can help in limiting the degradation of the ... applications, the market for biodegradable plastics can be broadly segmented into packaging, fibers, ...
Breaking Biology Technology:ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 2ImageXpress Micro Confocal High-Content Imaging System Expands the Boundaries of Research 3Neuro Advance Boston Brings Together Leading Neuroscience Experts on October 14 at Harvard Medical School 2Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 2Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 2Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 4Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 5
... new product pipeline provide positive outlook , ,CHIPPEWA ... lay off workers at its Chippewa Falls plant in ... a recorded a significant increased order backlog of $126 ... and up from $75 million in the previous quarter. ...
... is a good metaphor for the apparently holey (as in Swiss ... to get life science companies off the ground. , ,This ... so the tapestry doesnt fall apart. Last weeks column evoked responses ... mentioning other seed and early stage life science VCs or angel ...
... innovators, would regulators have anything to do? , ,Four ... reminder that for every breakthrough in fields such as ... slow the sprint toward progress. , ,That wouldnt be ... based on scientific inquiry, but sometimes the barriers are ...
Cached Biology Technology:Cray reports $54.5 million loss, plans layoff in Chippewa Falls 2Cray reports $54.5 million loss, plans layoff in Chippewa Falls 3More Midwest Seed-Stage Life Science VCs 2More Midwest Seed-Stage Life Science VCs 3More Midwest Seed-Stage Life Science VCs 4More Midwest Seed-Stage Life Science VCs 5More Midwest Seed-Stage Life Science VCs 6Technology regulation spurred by a mix of science and politics 2Technology regulation spurred by a mix of science and politics 3
Mouse monoclonal to OCIL ( Abpromise for all tested applications)....
... GenBank Accession Number : NM_201222 ... corresponding to amino acids 161-176 ... antiserum in 0.05% sodium azide ... routinely evaluated by immunoblot on ...
The FailSafe™ PROBES Real-Time PCR System enables rapid, precise optimization of PCR experiments in which the product is detected using fluorescent target-specific labeled probes....
Immunofixation Gel Kit, requires IF100 Reactivity: Human Applications: Immunofixation ...
Biology Products: