Navigation Links
Living anti-HIV gel shows early promise

Scientists are one step closer to developing a 'living gel' that could be applied to the vaginal or intestinal tracts to protect against HIV/AIDS infection.

The researchers genetically modified bacteria that are normally present in the body to make them produce a protein that stops the HIV virus from infecting cells.

They say that allowing these bacteria to colonise the internal body surfaces where HIV transmission can occur through sexual activity, could offer cost-effective, efficient and long-lasting protection against the virus.

The team, led by Srinivas Rao, chief of laboratory animal medicine at the Vaccine Research Center of the US National Institute of Allergy and Infectious Diseases, published their findings last week (23 August) in Proceedings of the National Academy of Sciences.

Rao's team showed that the modified bacteria colonised the intestines and vaginas of mice for periods of weeks to months, without causing any signs of disease. Furthermore, the modified bacteria produced large quantities of the HIV-blocking protein.

The reproductive and intestinal tracts are prime sites for HIV infection. Various microbes live in each, playing an important role in defending the body against harmful organisms.

The researchers hope that adding modified bacteria to these existing microbes could help prevent HIV transmission, especially in developing countries. They point out that if the bacteria successfully colonise and reproduce, protection can be long-lasting.

Short-lasting creams against HIV/AIDS would need to be applied regularly before sex and this is likely to limit their use, say the researchers.

In an article published yesterday (August 30) in the Proceedings of the National Academy of Sciences, Laurel Lagenaur and Edward Berger of the US National Institutes of Health, point out that modified bacteria would be easy to produce, store and distribute.

But they add that before human trials ca
'"/>

Source:SciDev.Net


Page: 1 2

Related biology news :

1. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
2. Living with salt
3. Living taste cells produced outside the body
4. Living laboratory found on shoreline statues
5. Study: Living coral reefs provide better protection from tsunami waves
6. Living view in animals shows how cells decide to make proteins
7. Living with water scarcity -- world must act now
8. Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
9. Resistance to anti-HIV drugs in Uganda developed due to drug supply problems
10. Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
11. “Nano-scissors?laser shows precise surgical capability

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Living anti HIV gel shows early promise

(Date:12/1/2009)... cell degeneration plays a crucial role. In the fu...ved from steering the generation and/or migration ...he current issue of the renowned journal Nature N...esis the process of nerve cell development was c... textbooks asserted that dead nerve cells could no...
(Date:12/1/2009)...er researchers have developed a tumor-attacking v...the growth of new tumor blood vessels. , Their r... cells oncolytic viruses might be more effective...y a gene for a protein that inhibits blood-vessel ...ormally produced in the brain. In this study, an o...
(Date:12/1/2009)...m Grand Prix., Every year since 2000, Inserm has...tanding,work performed in its laboratories and de...,demonstrate the diversity and wealth of activiti...alth research, and the creativity and passion of t...earch each day. The Inserm 2009 prize-giving cerem...
Breaking Biology News(10 mins):New source discovered for the generation of nerve cells in the brain 2Tumor-attacking virus strikes with 'one-two punch' 2Yehezkel Ben-Ari, winner of the 2009 INSERM Grand Prix 2Yehezkel Ben-Ari, winner of the 2009 INSERM Grand Prix 3BioSyntech Reports Positive Results from Pivotal Trial for BST CarGel 28R 29 Cartilage Repair Device 12670 1BioSyntech Reports Positive Results from Pivotal Trial for BST CarGel 28R 29 Cartilage Repair Device 12670 2BioSyntech Reports Positive Results from Pivotal Trial for BST CarGel 28R 29 Cartilage Repair Device 12670 3BioSyntech Reports Positive Results from Pivotal Trial for BST CarGel 28R 29 Cartilage Repair Device 12670 4BioSyntech Reports Positive Results from Pivotal Trial for BST CarGel 28R 29 Cartilage Repair Device 12670 5Nuvilex Renews MedX Master Distribution Agreement and Implements New Pricing for Talsyn Scar Cream 49191 1Nuvilex Renews MedX Master Distribution Agreement and Implements New Pricing for Talsyn Scar Cream 49191 2Nuvilex Renews MedX Master Distribution Agreement and Implements New Pricing for Talsyn Scar Cream 49191 3Mylan Receives FDA Approval for Additional Strength of Generic Restoril 28R 29 49186 1
...he leading figures in stem cell science will prese...his revolutionary field of research at The New Yor...slational Stem Cell Research Conference, October 1...The conference will focus on the dramatic advancem... understanding of the major diseases of our time -...
...less Data Communications Link School ....J., Aug. 20 BIO-key International,Inc. (OTC Bull...ric,identification and wireless public safety solu...RO(TM) and MobileCampus(TM), silent, secure,emerge...s and higher,education, respectively., MobileSRO ...
...How about a strawberry-flavored banana? Biochemist...ston say the day may be coming when scientists wil...vors in fruits and vegetables. In addition, it cou..., In the advance online publication of Nature o....S. Raman, Ph.D., and his colleagues report that t...
Other Biology News:New York Stem Cell Foundation announces third annual Translational Stem Cell Research Conference 2New York Stem Cell Foundation announces third annual Translational Stem Cell Research Conference 3BIO-key(R) Announces Emergency Alert and Management Solutions for Schools and Campuses 2BIO-key(R) Announces Emergency Alert and Management Solutions for Schools and Campuses 3Biochemists manipulate fruit flavor enzymes 2
(Date:12/1/2009)...c. 1 Reportlinker.com announces th...s catalogue: ,, Emerging Clinical Trial Locati...ging healthcare and regulatory environment ,, ...nical-Trial-Locations---Eastern-Europe-Market-dyna...vironment.html ,, Over the last decade pharmac...
(Date:12/1/2009)...Dec. 1 Expanding its European reac...of Sarasota has appointed Lake Chemicals and Miner...cated near Birmingham, England. ,, Osprey bree...e agricultural, waste water, and environmental mar...en drain fields, and clean up industrial and marin...
(Date:12/1/2009)...ruent Software agrees to migrate their Microsoft D...lients) to Synergy Business Solutions to maintain ...e, WA (PRWEB) December 1, 2009 -- Synergy Business...rosoft Dynamics SL practice of Congruent Software,...move was necessary due to a change in Congruent So...
(Date:12/1/2009)..., China, Dec. 1 /PRNewswire-Asia-FirstCall/ -- Chi...or "the Company") (Nasdaq: CSKI ), a leading,full... producing,over-the-counter drugs in the People,s ...e Company has engaged Guangdong Mediacy Kind Medic...ve as its exclusive sales agent for the,Company,s ...
Breaking Biology Technology:Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 2Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 3Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 4Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 5Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 6Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 7Reportlinker Adds Emerging Clinical Trial Locations - Eastern Europe: Market Dynamics and the Changing Healthcare and Regulatory Environment 8Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 2Synergy Business Solutions Acquires the Microsoft Dynamics SL Practice of Congruent Software, Inc. 3China Sky One Medical, Inc. Signs Distribution Agreement with MDK for the Sale of Two Diagnostic Kits in Southeast Asia 2China Sky One Medical, Inc. Signs Distribution Agreement with MDK for the Sale of Two Diagnostic Kits in Southeast Asia 3
...oyle , whose "Grow Wisconsin" economic development... for the state, has signed a bill that removes fro...t to capital formation , ,With little fanfare, Doy...roups, including the Wisconsin Economic Developmen...lity provision in state statutes that held shareho...
...aken for granted was the quality of sound on voice..., they emphasized that "you can hear a pin drop" a...nfrastructure. , ,The old Bell system also had ve...ity. It focused on moving from analog to digital l...ally regenerated the square wave signal rather tha...
...Semiconductor Corp. , the Ottawa, Ontario-based de...ons and computing markets, has announced the acqui...h-end chip design company based in Eau Claire, for...Eau Claire as a division of Tundra Semiconductor C...cations and computer chip for large networking and...
Other Biology Technology:Doyle repeals shareholder liability 2Is traditional voice quality an oxymoron with today's cellular, VoIP? 2Is traditional voice quality an oxymoron with today's cellular, VoIP? 3Canadian firm acquires Silicon Logic 2
Rabbit Anti-MAL Polyclonal Antibody, Unconjugated from Abcam
Rabbit Anti-Human ADAM-12 (Meltrin alpha), amino terminal region Antibody, Unconjugated from CEDARLANE Laboratories Limited
Rabbit Anti-FLIP Polyclonal Antibody, Unconjugated from Abcam
Mouse Anti-MDMA Monoclonal Antibody, Unconjugated, Clone 3G8 from Abcam
Biology Products: