Navigation Links
Live Recombinant Adenovirus Vaccine Technique Explored

HPV major capsid protein (L1) provides effective immunity to HPV infection. Dr. Ketner and his colleagues theorized that a live recombinant adenovirus could be made to express L1 as the virus replicated in the body and thereby create a lasting immune response. The researchers inserted the L1 gene into a live adenovirus such that it would be expressed using the virus' own late-gene expression machinery. L1 is expressed at very high levels in some recombinants.

Dr. Ketner believes that the replicating live recombinant adenovirus model shows promise as a means of developing economical and long-lasting vaccines for many illnesses. Ongoing research is aimed at determining the effectiveness of recombinants in animals.

Additional authors of “Viable adenovirus vaccine prototypes: High-level production of a papillomavirus capsid antigen from the major late transcriptional unit?include Michael Berg, Julie DiFatta and Egbert Hoiczyk of the W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health. Author Richard Schlegel is with the Department of Pathology at the Georgetown University Medical Center.

Funding was provided by grants from the National Institutes of Health.


'"/>

Source:Johns Hopkins Bloomberg School Of Public Health


Page: 1 2

Related biology news :

1. Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs
2. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
3. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
4. NIAID Initiates Trial of Experimental Avian Flu Vaccine
5. Study Models Impact Of Anthrax Vaccine
6. New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
7. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
8. EuroVacc 02 HIV Vaccine Trial Begins
9. Active Vaccine Prevents Mice From Developing Prion Disease
10. New Vaccine To Be Used For First Time In Polio Outbreak Response
11. Boosting The BCG Vaccine To Beat Tuberculosis
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Live Recombinant Adenovirus Vaccine Technique Explored

(Date:8/20/2014)... image of the Para and Mato Grosso states of ... set in order to deforest the land. Deforestation is ... where the land is thereafter converted to a nonforest ... farms, ranches, or urban use. The herringbone-patterned tan lines ... in the middle of the image are evidence of ...
(Date:8/20/2014)... Area Lyme Foundation, which aims to make Lyme disease ... research published in an upcoming issue of the Elsevier ... The findings show that ticks that carry Lyme ... making the threat of Lyme disease year-round. The research ... Health (CDPH) Vector-borne Disease Section and University of California, ...
(Date:8/20/2014)... the rare type of skin cancer that caused reggae ... more common types of skin cancer, according to a study ... & Melanoma Research . , Acral melanoma most often affects ... and other hairless parts of the skin. Unlike other more ... from the sun. , The team, from the Cancer Research ...
Breaking Biology News(10 mins):Lyme disease risk is year-round in Northwest California, according to new study 2Lyme disease risk is year-round in Northwest California, according to new study 3Scientists learn more about rare skin cancer that killed Bob Marley 2
... Binge drinking is often considered to be a problem of ... access journal BMC Public Health shows that binge ... thought. Dr Carolin Donath, from the Psychiatric University Clinic Erlangen, ... year olds in Germany and found that more than 93% of ...
... complex feat of nanoengineering, a team of scientists at ... in creating a programable molecular transport system, the workings ... results, appearing in the latest issue of Nature ... advanced drug delivery methods and molecular manufacturing systems. ...
... links between 29 regions of the genome and ulcerative colitis ... new findings increase the total number of genome regions known ... The results point to several biological processes, including the way ... which are likely to play an important role in the ...
Cached Biology News:Research links 29 genome regions with common form of inflammatory bowel disease 2Research links 29 genome regions with common form of inflammatory bowel disease 3
(Date:8/21/2014)... MA (PRWEB) August 21, 2014 ... company, has been recognized as one of the ... | 5000 magazine for the 2nd consecutive year. ... its 33rd annual Inc. 500|5000, an exclusive ranking ... represents the most comprehensive look at the most ...
(Date:8/20/2014)... the first time, chemists have succeeded in measuring vibrational ... resolution. The study reveals how vibration of a single ... , The study was performed at the University ... the University of Jyvskyl works as a visiting fellow ... the study. The second team was lead by Professor ...
(Date:8/20/2014)... August 20, 2014 The 6th ... being held on October 29-30 in San Francisco, CA. ... academic and government researchers and clinicians focused on addressing ... , In the twelve years since the sequencing ... have been introduced with pharmacogenetic information in the label ...
(Date:8/20/2014)... August 20, 2014 GraphDB™ ... today including improvements to the enterprise replication cluster, ... for Lucene, SOLR and Elasticsearch. This release happens ... high performance triplestore – GraphDB™ was formerly known ... deploying the only mature enterprise resilient RDF triplestore ...
Breaking Biology Technology:SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Seeing a molecule breathe 26th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4
... $215 million , , Acquisition will ... , CARLSBAD, Calif. and ABBOTT PARK, Ill., ... and Abbott (NYSE: ABT ) announced today that Abbott ... Ibis Biosciences, Inc., an Isis subsidiary, for a closing purchase price ...
... Trusted LASIK Surgeons directory service and website at ... consumers seeking to improve their vision. What sets the ... process ensuring that only those who are among the ... in the United States are listed. Refractive eye surgeons, ...
... retina cells or other tissues can be tracked by ... record of movement and gene expression. The new technique, ... , will allow detailed analyses of correlations between behavior, ... team of researchers from the University of Southern California, ...
Cached Biology Technology:Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 2Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 3Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 4Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 5Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 2Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 3Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 4Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 5Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 6Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 7
... Macro-Prep ion exchange media are rigid macroporous ... high flow rates at moderate pressures, while ... sites, and the hydrophilic matrix reduces nonspecific ... high-capacity strong anion exchanger with very high ...
... a cocktail of 3 siRNAs specifically targeted ... most popular product. The siTrio reagent guarantees ... your target gene when used under standard ... confirmation of optimal transfection with one of ...
... The IDS 25-Hydroxy Vitamin D kit ... quantitative determination of 25-hydroxyvitamin D (25-OH ... human serum or plasma. Our patented ... of solvent precipitation and centrifugation and ...
... multi-purpose, high gel-strength agarose suitable for a ... conventional constant field to Pulsed Field Gel ... strength and exclusion limits, Multi ABgarose can ... running times. This in turn means reduced ...
Biology Products: