Navigation Links
Lithium builds gray matter in bipolar brains, UCLA study shows

ct the bipolar brain."

Although other studies have measured increases in the overall volume of the brain, Bearden said, this imaging method allowed the researchers to see exactly which brain regions were affected by lithium.

"Bipolar patients who were taking lithium had a striking increase in gray matter in the cingulate and paralimbic regions of the brain," she said. "These regions regulate attention, motivation and emotion, which are profoundly affected in bipolar illness."

While conventional MRI studies have measured brain volume in total, this new image analysis allows researchers to examine differences in cortical anatomy at a much greater spatial resolution.

In this study, Bearden and colleagues at UCLA used computer analysis to analyze brain scans collected by collaborators at the University of Pittsburgh in order to determine whether bipolar patients showed changes in brain tissue and, if so, whether those changes were influenced by lithium treatment. Specifically, they employed high-resolution MRI and cortical pattern-matching methods to map gray matter differences in 28 adults with bipolar disorder ?70 percent of whom were lithium-treated ?and 28 healthy control subjects. Detailed spatial analyses of gray matter distribution were conducted by measuring local volumes of gray matter at thousands of locations in the brain.

While the brains of lithium-treated bipolar patients did not differ from those of the control subjects in total white-matter volume, their overall gray-matter volume was significantly higher, sometimes by as much as 15 percent.

Unfortunately, said Bearden, there is no evidence that the increase in gray matter persists if lithium treatment is discontinued. "But it does suggest that lithium can have dramatic effects on gray matter in the brain," she said. "This may be an important clue as to how and why it works."
'"/>

Source:University of California - Los Angeles


Page: 1 2

Related biology news :

1. Signaling protein builds bigger, better bones in mice
2. New MRI technique quickly builds 3-D images of knees
3. Orange, grapefruit juice for breakfast builds bones in rats
4. Study shows enzyme builds neurotransmitters via newly discovered pathway
5. To sea or not to sea: When it comes to salmon sex, size sometimes doesnt matter
6. Size matters: Preventing large mammal extinction
7. Space matters: Estimating species diversity in the fossil record
8. Looks matter to female barn swallows
9. Bigger brain size matters for intellectual ability
10. UCSB researchers discover shape matters to macrophages
11. Researchers find that bumblebees flower choice matters
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Lithium builds gray matter bipolar brains UCLA study shows

(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric ... to industry leaders such as Intel, Jabra, Atlas, and ... wearable products. These products will be showcased at CES ... Vegas . "Our partners choose ... robust – with the clinical data to back it ...
(Date:12/15/2014)... 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a ... recognition system measures the overall facial feature of ... and the distance between eyes. Facial recognition is ...
(Date:12/11/2014)... N.C. , Dec. 10, 2014  That blood pressure ... quite a while. Hypertension – the medical term for high ... the early 1800s, and the inflatable cuff that,s used in ... doesn,t, however, mean there,s nothing new about hypertension, its triggers ... long-held beliefs about the condition and the best ways to ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... key features that distinguish influenza viruses found in birds from ... used a mathematical technique to identify specific amino acid building ... influenza virus proteins and those that are more likely to ... amino acids can be used as markers to track changes ...
... study in the August 21st issue of Current Biology, a ... evidence in support of the long-held notion that men and ... the researchers found that women really do prefer pinkor at ... we expected to find sex differences, we were surprised at ...
... fuel, gasoline, carbon anodes and heating oil may be ... refinery by-products, according to a team of Penn State ... work that we have been doing for a long ... Penn State,s Energy Institute. "Our aim is to integrate ...
Cached Biology News:St. Jude influenza survey uncovers key differences between bird flu and human flu 2St. Jude influenza survey uncovers key differences between bird flu and human flu 3Girls prefer pink, or at least a redder shade of blue 2Coal-based fuels and products hit the refinery 2
(Date:12/19/2014)... Calif. , Dec. 19, 2014  Roche (SIX: ... of Bina Technologies, Inc. (Bina), a privately held ... , USA. Bina provides a big data ... generation sequencing (NGS) data. Bina,s proprietary on-market Genomic ... and academic researchers to perform fast and scalable ...
(Date:12/19/2014)... Arkansas (PRWEB) December 18, 2014 ... to locate its pilot production facility and future ... develop and produce innovative new materials that safely ... chosen not only because of its historic, strong ... leaders’ efforts to attract leading edge, technology-based companies ...
(Date:12/19/2014)... 19, 2014 In contrast to traditional ... with various colors, Valoya uses proprietary LED technology to ... best possible uniformity which is critical in low proximity ... spectral accuracy throughout its lifetime which is up to ... , "The investment cost was clearly higher when ...
(Date:12/19/2014)...   ISN has released its third annual ... publication series. With data aggregated from over eight ... within its online contractor management platform, ISNetworld, this three-part ... (KPI) statistics. The Contractor ... is available in two industry specific volumes: Oil ...
Breaking Biology Technology:Roche acquires Bina Technologies and enters the genomic informatics market 2Roche acquires Bina Technologies and enters the genomic informatics market 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... SuperPower, University of Houston, Oak Ridge National Laboratory and ... smart grid demonstration project award announced by U.S. Department ... funds will be used to manufacture a transformer for ... nation,s power grid. , "The project is for ...
... SHANGHAI, Dec. 22 /PRNewswire-Asia/ -- Sundia MediTech, a leading,pharmaceutical ... has received 2009 Deloitte Technology Fast 500 Asia Pacific award.,This ... news was,announced at a ceremony on December 10, 2009 at ... The Deloitte Technology Fast 500 Asia Pacific program is now ...
... , www.bioheartinc.com , The Bioheart ... large quantity of stem cells can be obtained from a patient,s ... cheaply. Adipose stem cells are capable of promoting blood vessel ... Lower limb ischemia is pain, often severe enough to be intolerable, ...
Cached Biology Technology:Waukesha Electric partners with SuperPower and UH to build fault current limiting superconducting transformer for Dept. of Energy 2Waukesha Electric partners with SuperPower and UH to build fault current limiting superconducting transformer for Dept. of Energy 3Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue 2Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue 3Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue 4Bioheart Makes Breakthrough in Critical Limb Ischemia Therapy with Stem Cells Obtained from Fat Tissue 5
... of Total Canine Endostatin. Canine ... Science products include a line of ... and reagents used for multiple research ... kits are ultra-sensitive, quick and dependable ...
... Kit is a very sensitive immunohistochemical tool ... containing both anti-von Willebrand Factor and anti-CD31 ... variety of species. This AP kit provides ... of frozen and paraffin-embedded sections in human ...
... Many modifications of Eagle's ... the original formulation. The most ... Modified Eagle's,Medium. DME is a ... Eagle [MEM] that contains a ...
... OligoMix or individual RNA sequences from high throughput ... small RNAs from LC Sciences. These products provide ... millions) of DESIGNED sequences delivered in a microtube ... containing a single verified RNA sequence. This is ...
Biology Products: