Navigation Links
Like salty food? Chances are you had low blood sodium when you were born

A new study concludes that low birthweight babies born with low sodium (salt) in their blood serum will likely consume large quantities of dietary sodium later in life. In the study, researchers also found that newborns with the most severe cases of low sodium blood serum consumed ~1700 mg more sodium per day and weighed some 30 percent more than their peers. These data, taken together with other recent findings, make it clear that very low serum sodium in pre-term and new born infants is a consistent and significant contributing factor for long-term sodium intake, a key marker for obesity.

The results are from the study "Lowest Neonatal Serum Sodium Predicts Sodium Intake in Low-Birthweight Children," conducted by Adi Shirazki, Edith Gershon, and Micah Leshem, all of the University of Haifa, Haifa; Zalman Weintraub of the Galilee Medical Center, Nahariya; and Dan Reich of the Ha'Emek Medical Center, Afula, Israel. The study is published in the American Journal of Physiology ?Regulatory, Integrative, and Comparative Physiology. The Journal is one of 11 peer-reviewed research journals published each month by the American Physiological Society (APS) (

The Study: Methodology
Forty-one children born prematurely and identified through the archives of the Ha'Emek and Galilee Medical Centers (Israel) participated in the investigation with the written permission of their guardians. The youngsters were admitted to the study based on whether they had received neonatal diuretic treatment during their first month of life (n=23) or were a matched control having received no diuretic treatment (n=18). Of the total, 21 were Arabs (14 boys, 7 girls) and 20 were Jews (11 boys, 9 girls), ranging between 8-15 years of age.

The researchers analyzed each child's sodium appetite according to neonatal diuretic treatment, and used each child's lowest recorded serum sodium levels as an index of sodium loss. The latter was determined by screening all the serum sodium measurements of each infant's postnatal medical record, and selecting the lowest.

Each child underwent a pediatric physical examination. To estimate current sodium appetite, participants were tested for their preferred concentration of salt in soup and sugar in tea, followed by orally administered spray tests involving table salt and table sugar. Between the tests the children and escorting parent(s) were interviewed about dietary and seasoning preferences. The children were then invited to eat freely from a table of salty and sweet snacks.

The researchers used trained experts to collect the above data. The investigators used ANOVA, correlational analysis (Spearman), and SPSS to analyze the data. Alpha was fixed at 0.05 and SEM was the measure of variability.

The Study: Results
Upon review of the data, the researchers concluded that:

  • reported dietary sodium consumption in childhood (ages 8-15) was predicted by neonatal lowest serum sodium (NLS) and not by neonatal diuretic treatment, as they originally proposed.

  • NLS predicted dietary sodium intake in both ethnic groups and both boys and girls.

  • the 14 children with the most severe NLS (serum sodium<130 mEq/L) ate double the number of salty snacks (p<0.05) and their dietary sodium intake was substantially higher -- 4515 ±310 mg/day vs. 3307± 248 (p=0.0054) -- than their peers.

  • no relationship was found between neonatal lowest serum sodium and a preference for salt per se. Rather, the preference was for the foods that contain it.

  • gestational age and birthweight were not predictors of childhood sodium intake.

The researchers concluded that low sodium blood serum in infants ?not gestational age, birthweight or neonatal diuretic treatment ?predicts an increased intake of d ietary sodium later in life. As neonatal serum sodium is a marker of future sodium intake, clinicians may wish to advise families of these children about the increased risk of sodium intake and obesity later in life.

Source:American Physiological Society

Related biology news :

1. A salty tale: New bacterial genome sequenced from ancient salterns
2. Microcapsules like it hot and salty
3. White blood cell waste disposal system plays critical regulatory role
4. Epstein-Barr virus protein crucial to its role in blood cancers
5. New insight into regulation of blood stem cells
6. Nano-bumps could help repair clogged blood vessels
7. First technology to remove prions that cause vCJD from blood launched
8. Breakthrough isolating embryo-quality stem cells from blood
9. Thai spice helps cut blood sugar swings
10. Study shows humans have ability to track odors, much like bloodhounds
11. Mad cow proteins successfully detected in blood

Post Your Comments:

(Date:11/9/2015)... DUBLIN , Nov. 09, 2015 /PRNewswire/ ... announced the addition of the "Global ... to their offering. --> ... "Global Law Enforcement Biometrics Market 2015-2019" ... Research and Markets ( ) ...
(Date:11/4/2015)... New York , November 4, 2015 ... to a new market report published by Transparency Market ... Share, Growth, Trends and Forecast 2015 - 2022", the global ... of US$ 30.3 bn by 2022. The market is ... the forecast period from 2015 to 2022. Rising security ...
(Date:10/29/2015)... , Oct. 29, 2015   MedNet Solutions ... the entire spectrum of clinical research, is pleased to ... High Tech Association (MHTA) as one of only three ... the "Software – Small and Growing" category. The Tekne Awards ... who have shown superior technology innovation and leadership. ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... and NEW YORK , November 24, 2015 ... by Bristol-Myers Squibb in a European ... Squibb Company in which the companies will work closely ... and other areas of unmet medical need. The collaboration is ... 5, the latest LSP fund. This is the first investment ...
(Date:11/24/2015)... NEW YORK , Nov. 24, 2015 According ... today than in 2005. This is something that many doctors, ... long time. One questions remains: with fewer PSA tests being ... cancer ? Dr. David Samadi, "Despite ... cancer, the disease remains the second leading cancer cause of ...
(Date:11/23/2015)...   Ceres, Inc . (Nasdaq: CERE ), ... the fiscal year ended August 31, 2015 and provided ... --> During fiscal year 2015, Ceres ... with a better balance of yield, energy and nutrition. ... several leading crop input providers and made significant progress ...
(Date:11/23/2015)... ... 2015 , ... Shimadzu Corporation announces that it has won ... system. The award from R&D magazine recognizes Shimadzu’s Nexera UC system as one ... analytical and testing category. R&D Magazine chose the Nexera UC system because its ...
Breaking Biology Technology: