Navigation Links
Lateral thinking produces first map of gene transmission

A University of Queensland study mapping the evolution of genes has shed light on the role of gene transfer in bacterial diseases.

The study, published recently in Proceedings of the National Academy of Sciences USA, was conducted by three scientists at UQ's Institute for Molecular Bioscience.

Dr Robert Beiko, Professor Mark Ragan and Mr Timothy Harlow examined the genomes of 144 species of bacteria, in an effort to map how genes are shared between bacteria.

The study highlights lateral genetic transfer ?a process where genes are transferred between organisms that aren't directly related.

The map has traced the paths of lateral gene transfer, from the bacteria that donated the genes to the ones that received them.

Their results clearly show genetic modification of organisms by lateral transfer is a widespread natural phenomenon, and it can occur even between distantly related organisms, although particularly those which live in a similar environment.

The discovery that lateral transfer is so widespread shows how disease-causing bacteria can quickly become resistant to treatment: a bacterium with genes that confer drug resistance can, through lateral transfer, rapidly spread them to other bacteria, instead of just to their own offspring.

From the early days of the science of genetics, it was assumed that transfer of genes could only be vertical, i.e. from parents to offspring.

But more recently, scientists have become aware of lateral genetic transfer, which occurs in bacteria through methods such as bacterial viruses and direct contact between cells.

"The idea of lateral genetic transfer has been around for a few years, but what was missing was a good, hard, rigorous look at it," Professor Ragan said.

"Previous studies have either been small scale, or used statistical shortcut methods."

The study is believed to be the largest biologically inspired computation carried ou t in Australia, with over 500, 000 hours of computing.

The scientists used the national supercomputing facility of the Australian Partnership in Advanced Computing.


'"/>

Source:Research Australia


Related biology news :

1. Shift of weather patterns necessitates rethinking of reforestation methods
2. Deep thinking: Scientists sequence a cold-loving marine microbe
3. New research puts a fresh spin on current thinking of speech evolution in humans
4. Scientists show how thinking can harm brain cells
5. Agriculture and tropical conservation: rethinking old ideas
6. Jefferson researchers discovery may change thinking on how viruses invade the brain
7. Common gene version optimizes thinking -- but with a possible downside
8. Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
9. Ultrasound upgrade produces images that work like 3-D movies
10. A genes first kiss sets off that affair known as puberty
11. Love at first smell
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/9/2016)...  Perkotek an innovation leader in attendance control systems is proud to announce the ... employers to make sure the right employees are actually signing in, and to even ... ... ... ...
(Date:6/7/2016)... TORONTO , June 7, 2016  Syngrafii ... begun a business relationship that includes integrating Syngrafii,s ... pilot branch project. This collaboration will result in ... for the credit union, while maintaining existing document ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
(Date:6/2/2016)... The Department of Transport Management (DOTM) ... million US Dollar project, for the , Supply ... Enrolment, and IT Infrastructure , to ... implementation of Identity Management Solutions. Numerous renowned international vendors participated ... was selected for the most compliant and innovative ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Calif. , June 23, 2016  Blueprint Bio, ... biological discoveries to the medical community, has closed its ... Matthew Nunez . "We have received ... with the capital we need to meet our current ... essentially provide us the runway to complete validation on ...
(Date:6/23/2016)... June 23, 2016 On Wednesday, June ... 4,833.32, down 0.22%; the Dow Jones Industrial Average edged 0.27% ... at 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the ... Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. ... BIND ). Learn more about these stocks by ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... focused on quality, regulatory and technical consulting, provides a free webinar ... presented on July 13, 2016 at 12pm CT at no charge. , Incomplete ...
(Date:6/23/2016)... SAN FRANCISCO , June 22, 2016  Amgen ... platinum sponsorship of the QB3@953 life sciences ... improve human health. The shared laboratory space at QB3@953 ... startups overcome a key obstacle for many early stage ... As part of the sponsorship, Amgen launched two "Amgen ...
Breaking Biology Technology: