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Langerhans cells regulate immune reactions in the skin

keepers with the environment, which poses a constant challenge to skin. Most such challenges are not dangerous and do not warrant an immune response."

Langerhans cells may function generally to prevent excessive responses in the skin. "Failure of this mechanism could result in chronic inflammatory skin conditions like lupus and psoriasis, said Shlomchik. "This is the new theory we would now like to test."

The findings could also have future implications for skin transplantation, autoimmune diseases and the immune system's ability to prevent skin cancer.


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Source:Yale University


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