Through utilization of the unparalleled polymer synthesis and R&D capabilities of Nitto Denko Corporation, Isis?outstanding oligonucleotide synthesis and drug development expertise and the worldwide marketing and customer support operations of Kinovate Life Sciences, this new product promises to deliver significantly improved technical and economic outcomes for all segments of the oligonucleotide industry.
Solid support is the base structure used in the synthesis of oligonucleotides, including diagnostic probes and primers, antisense including RNAi, microRNA, DNA-based and aptamer drugs and represents a substantial portion of the cost to manufacture these oligonucleotides.
NittoPhase?has been rigorously tested at both small and large scales, and has been observed to exhibit superior characteristics and performance when compared to other solid supports currently on the market. NittoPhase?has great potential to decrease manufacturing costs due to it’s significantly lower unit cost, as well as potentially higher yield and full length purity, reducing cost-of-goods. NittoPhase?will be commercially available in two grades; NittoPhaseTOS?for high loading applications, and NittoPhaseROS?for lower loading applications. In this way, NittoPhase?offers a solution for the entire spectrum of oligonucleotide synthesis applications.
“Kinovate Life Sciences aims to be a robust p