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Intensive statin therapy may partially reverse plaque build-up in arteries

estor®). IVUS provides a precise and reproducible method for determining the change in plaque, or atheroma, burden during treatment. Atherosclerosis progression was assessed at baseline and after at 24 months of treatment.

"Previous similar studies with statins have shown slowing of coronary disease, but not regression. This regimen significantly lowered bad cholesterol, and surprisingly, markedly increased good cholesterol levels," said Steven Nissen, M.D., F.A.C.C., of the Cleveland Clinic and lead author of the study. Dr. Nissen is also President-Elect of the American college of Cardiology. "We conclude that very low LDL levels (below current guidelines), when accompanied by raised HDL, can regress, or partially reverse, the plaque buildup in the coronary arteries."

Dr. Nissen will present the results of the "Effect of Very Low LDL-C Levels on Regression of Coronary Atherosclerosis: Results of the ASTEROID Trial" study on Monday, March 13 at 2:20 p.m.


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Source:American College of Cardiology


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