Navigation Links
Inflammatory molecules released by pollen trigger allergies

How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking compounds than do pollen from unpolluted areas, possibly explaining why allergies are more prevalent in places with high levels of car exhaust emissions.

Traidl-Hoffmann and colleagues showed that extracts from birch pollen and other common allergens block the production of a soluble protein by immune cells that normally inhibits allergic reactions. They went on to identify the compound in the pollen extracts that caused the inhibitory response and showed that it was similar to certain pro-inflammatory molecules produced in the body in response to injury or infection. The authors now plan to assess whether cells from allergy-prone people are more sensitive to the effects of the pollen-derived compound than those from non-allergic individuals. A better understanding of these molecules and how they work may eventually lead to new approaches to treating allergies.


Source:Journal of Experimental Medicine

Page: 1

Related biology news :

1. FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2. Medical molecules designed to respond to visible light that can penetrate tissue
3. DNA constraints control structure of attached macromolecules
4. Scientists discover that three molecules may be developed into new Alzheimers drugs
5. Physical and functional interaction of key cell growth molecules linked to cancer
6. Scientists discover new way to look at how molecules twist and turn on water
7. Scientists learn to predict protein-stabilizing ability of small molecules
8. Tiny RNA molecules fine-tune the brains synapses
9. Convergent evolution of molecules in electric fish
10. Micro-boxes of water used to study single molecules
11. Researchers unveil strategy for creating actively-programmed anti-cancer molecules
Post Your Comments:

(Date:11/19/2015)... , Nov. 19, 2015  Although some 350 ... is dominated by a few companies, according to Kalorama ... own 51% of the market share of the 6.1 ... The World Market for Molecular Diagnostic s . ... "The market is still controlled by one company and ...
(Date:11/17/2015)... LIVERMORE, Calif. , Nov. 17, 2015  Vigilant ... has joined its Board of Directors. ... Vigilant,s Board after recently retiring from the partnership at ... owning 107 companies with over $140 Billion in revenue.  ... performance improvement across all the TPG companies, from 1997 ...
(Date:11/12/2015)... LONDON , Nov. 11, 2015   ... and reliable analytical tools has been paving the ... and qualitative determination of discrete analytes in clinical, ... sensors are being predominantly used in medical applications, ... and environmental sectors due to continuous emphasis on ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... KUALA LUMPUR, Malaysia , Nov. 24, 2015 ... the global contract research organisation (CRO) market. The ... to result in lower margins but higher volume ... With increased capacity and scale, however, margins in ... Contract Research Organisation (CRO) Market ( ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... metabolism. But unless it is bound to proteins, copper is also toxic to ... researchers at Worcester Polytechnic Institute (WPI) will conduct a systematic study of copper ...
(Date:11/24/2015)... ... November 24, 2015 , ... This fall, global software solutions leader ... five states to develop and pitch their BIG ideas to improve health and wellness ... competing for votes to win the title of SAP's Teen Innovator, an all-expenses paid ...
(Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna ... announced today that the remaining 11,000 post-share consolidation ... Purchase Warrants (the "Series B Warrants") subject to ... exercised on November 23, 2015, which will result ... After giving effect to the issuance of such ...
Breaking Biology Technology: