Navigation Links
Inflammation and drugs to control this activity studied in a variety of tumors sites

yzed 84 subsequent biopsies performed within five years in patients who had initially shown chronic prostate inflammation. In the follow up, 29 new cancer cases were diagnosed: six occurred in patients in whom initial biopsies showed only chronic inflammation, 15 in patients with initial PAH/PIA lesions, along with eight in patients with chronic inflammation and other risk factors for cancer (high-grade prostate intraepithelial neoplasia and atypical small acinar proliferation that may have been cancerous).

In contrast, the researchers found only two cases ?six percent ?in the 33 patients without inflammation who went on to develop cancer, both of whom had other risk factors for cancer.

"We observed a significant association between serum PSA and the degree of chronic inflammation," said Gupta, which was expected based on previous findings.

"The first concern is, should patients with initial biopsies showing no malignancy but showing chronic inflammation be followed more closely and perhaps re-biopsied more frequently?" Gupta said.

Gupta's group plans future studies that will be similar in design, but have a larger number of subjects.

COX-2 Expression in Atypia: Correlation with Breast Cancer Risk: Abstract No. 2353

Women with atypical hyperplasia who also have high levels of the enzyme COX-2 in their breast tissue were more likely to develop breast cancer than women with lower levels of the enzyme.

According to Lynn Hartmann, M.D., professor of oncology at the Mayo Clinic College of Medicine in Rochester, Minn., about one million women a year have a breast biopsy with benign findings (sometimes called benign breast disease). One form of benign breast disease, atypical hyperplasia, or atypia, is characterized by abnormal cell growth and can be precancerous. Women with this condition have a four times greater risk of developing breast cancer.

Hartmann and her co-workers wanted to find out whethe
'"/>

Source:American Association for Cancer Research


Page: 1 2 3 4 5 6 7 8 9

Related biology news :

1. How an AIDS-Related Cancer Unleashes Inflammation
2. Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
3. Inflammation markers identify fatigue in breast cancer survivors
4. Inflammation may play role in metastasis of prostate cancer
5. Molecular machine may lead to new drugs to combat human diseases
6. Researchers identify target for cancer drugs
7. MetaChip provides quick, efficient toxicity screening of potential drugs
8. Newly discovered pathway might help in design of cancer drugs
9. UNC launches study of liver injury caused by drugs
10. Findings have implications for tracking disease, drugs at the molecular level
11. Future diabetes drugs may target new protein interaction
Post Your Comments:
(Date:8/19/2014)... fish purchased at retail seafood counters in 10 ... can expose consumers to unexpectedly high levels of ... falsely present a fish of the same species, ... dangerous mislabeling offense, according to new research by ... labeling of seafood is essential to allow consumers ...
(Date:8/19/2014)... Scientists at the Houston Methodist Research Institute have figured ... using a pipette -- a common laboratory tool that,s ... preliminary test results in a recent issue of the ... "Studying single cells and their unique functions has become ... faculty member Lidong Qin, Ph.D., the project,s principal investigator. ...
(Date:8/19/2014)... Anyone who has ever had a glass of fizzy ... the air. But in a finding with wide industrial ... push some particles down into the liquid as well. ... aerosol droplets, so we were surprised, and fascinated, to ... the same process injected tiny oil droplets into the ...
Breaking Biology News(10 mins):Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3Moving single cells around -- accurately and cheaply 2Bubbling down: Discovery suggests surprising uses for common bubbles 2Bubbling down: Discovery suggests surprising uses for common bubbles 3
... battle to reduce carbon emissions is at the heart ... of Missouri have discovered that nature has been lending ... in the Department of Forestry discovered that trees submerged ... years, a significantly longer period of time than trees ...
... grew wild in Mexico and were radically different from ... important crops in the world. While the ... Mexico, the time and location of the earliest domestication ... Now, in addition to more traditional macrobotanical and archeological ...
... A detailed analysis of data from nearly 50 ... adjacent Rhode Island Sound has revealed a long-term shift ... effects of global warming. According to Jeremy Collie, ... Graduate School of Oceanography, the fish community has shifted ...
Cached Biology News:Ancient oak trees help reduce global warming 2Early origins of maize in Mexico 2Early origins of maize in Mexico 3Climate change causing significant shift in composition of coastal fish communities 2Climate change causing significant shift in composition of coastal fish communities 3
(Date:8/19/2014)... Shimadzu Scientific Instruments has introduced two ... adding to the company’s extensive line-up of HPLC ... operating environment, and full automation, the i-Series provides ... conventional to ultra-high-speed analysis. , The ... so users can begin building the lab of ...
(Date:8/19/2014)... (PRWEB) August 19, 2014 ... to raise $200,000 to fund a corporate lab ... , This development is a critical component ... of care to the implementation of personalized medicine ... of practicing medicine. , Indiegogo contributions will support ...
(Date:8/19/2014)... August 19, 2014 XenoTech announces ... and cost-effective metabolite production from bioactive small molecules. ... platform, the technology enables convenient and timely assessment ... to XenoTech’s Vice President of Commercial Operations, Christian ... assessing clinical risk can be measured directly by ...
(Date:8/19/2014)... 2012, the European Union (EU) mandated use of the ICH-recommended ... – responding to the increasing need to understand and manage ... many regions, the main objectives of the PBRER are to:, ... of new or emerging information on the risks of a ... potential benefits of a drug; and , Allow ...
Breaking Biology Technology:Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 2Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 3Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 2Cellgen Diagnostics Launches Indiegogo Crowdfunding Campaign for DNA Medical Testing Device 3Beyond Metabolite Identification, Testable Quantities Now Offered by XenoTech 2Beyond Metabolite Identification, Testable Quantities Now Offered by XenoTech 3Top Five Best Practices for Developing Your Periodic Benefit Risk Evaluation Report (PBRER), New Webinar Hosted by Xtalks 2
... Washington, D.C. - With the opening of a ... Gov. Jim Doyle again urged Senators to overturn ... research. , ,During a morning visit to the West Salem home ... Doyle again used the backdrop of a Wisconsin family with a ...
... the banking and payments technology subsidiary of Marshall ... a new cash-management division and the appointment of its ... , ,Kasik will run the division, which will allow ... income statement items, payables, and receivables with full accounting ...
... - The United States Senate, by a vote of 63-37, ... ban on new federal funding for embryonic stem cell research, setting ... short of the 67 votes needed to override a veto, which ... bill, known as the Stem Cell Research Enhancement Act , ...
Cached Biology Technology:Doyle urges Senate to loosen stem cell restrictions 2Doyle urges Senate to loosen stem cell restrictions 3Doyle urges Senate to loosen stem cell restrictions 4Senate approves bill to expand stem cell funding 2
...
BD BaculoGoldTM Transfection Kit 5 transfections...
... Purification Kit is designed for isolating DNA from ... protocol can be completed in less than one ... larger amounts of DNA. The purified DNA can ... Southern blotting. The MasterPure Kit was designed for ...
...
Biology Products: