Navigation Links
Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

rns survived transplant, whereas only 43 percent of the symptomatic babies survived, the study showed.

While the child's age and symptom severity at the time of transplant are crucial to determining outcome, the source of stem cells is also important, said Kurtzberg.

Cord blood appears to provide a better and faster correction of enzyme deficiencies than does adult bone marrow, she said. Stem cells from cord blood travel to the brain more rapidly than stem cells from adult bone marrow, and cord blood stem cells repair deficiencies in both the central and peripheral nervous systems, said Kurtzberg.

Thus, disease progression stabilizes about 2 to 4 months earlier in patients who receive cord blood compared to those who receive adult bone marrow, and huge developmental milestones occur during that period of infancy, said Kurtzberg.

The ease of obtaining cord blood also makes it an excellent source of stem cells, she said. Cord blood is readily available because it is extracted from discarded placentas (afterbirth) following child birth. Adult bone marrow must be harvested from living donors through an invasive surgical procedure.

Finally, cord blood cells are less mature than adult bone marrow cells and thus do not need to perfectly match the patient's immune-related blood proteins, called antigens, said Kurtzberg. Only four of six cord blood "antigens" must match for a transplant to have a reasonable chance of success, whereas adult bone marrow requires a greater degree of matching antigens, she said.

As a result, a cord blood donor unit can be identified and obtained within a week, whereas a matching adult donor can takes months to locate and obtain if available at all, said Kurtzberg.

Similar benefits of cord blood were seen in an earlier Duke study of children with Hurler Syndrome, results of which were published in the May 6, 2004, issue of the New England Journal of Medicine. In that study, Kurtzberg's team
'"/>

Source:DukeHealth


Page: 1 2 3 4

Related biology news :

1. Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
2. Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants
3. Infants can organise visual information at just four months
4. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
5. Genetically modified natural killer immune cells attack, kill leukemia cells
6. Ants Genetic Engineering Leads To Species Interdependency
7. Genetic Variation Visualization - From EMBL
8. Genetically modified rice in China benefits farmers health, study finds
9. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
10. Genetic defects give the immune system the green light to attack the pancreas
11. Maine Researchers Find Exceptions to Old Rules of Genetic Inheritance
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Infants with Rare Genetic Disease Saved Cord Blood Stem Cells

(Date:12/11/2014)... Minn. , Dec. 10, 2014  Data ... physiologic monitoring, has released a new series of ... of preclinical toxicology researchers. M series, part of ... toxicologists collect the best possible physiologic data when ... Adding functional endpoints to toxicology studies has ...
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Valencell, a ... it is seeing a staggering demand from its licensees ... the Company revealed, is not solely coming from fitness ... as well. "A wearable is only as ... result, accuracy is the ultimate driver in long-term mass ...
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 ... and collaboration catalyst that provides the connective tissue that ... by enabling them to easily share client-level information; earned ... Foundation to expand to organizations serving seniors aging in ... San Diego" partner on December 11 th 4-6p. ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... URBANA The University of Illinois scientists who ... cancer have developed a tool that will help them ... body. And they,ve secured funding from the National Institutes ... carotenoidsthe pigments that give the red, yellow, and orange ...
... the New York Academy of Sciences on December 9 ... science and policy initiatives addressing the global and national ... The Global Obesity Epidemic, is presented by the Academy ... with support from the new Sackler Institute for Nutrition ...
... work in protecting the lives and livelihoods of some of ... national award. At the Times Higher Education awards ceremony ... School of Planning, Architecture and Civil Engineering received the Outstanding ... recognises the team,s work in tackling the world,s worst case ...
Cached Biology News:U of I scientists develop tool to trace metabolism of cancer-fighting tomato compounds 2Super-sized world: Conference addresses global obesity epidemic, explores policies, interventions 2Queen's life-saving research wins education 'Oscar' 2
(Date:12/24/2014)... St. Louis, Missouri (PRWEB) December 23, 2014 ... and targeting Swiss biotechnology company, Syngenta, are in the ... for pretrial proceedings. The consolidated case is In Re: ... in the U.S. District Court for the District of ... litigation (MDL) has been handed over to U.S. District ...
(Date:12/24/2014)... Texas (PRWEB) December 23, 2014 ... methyl mercaptan such as its definition, classification, ... presents product specification, manufacturing process, and product ... technology and applications. The analysis also covers ... marketing channels, industry development trend and proposals. ...
(Date:12/24/2014)... Texas , Dec. 23, 2014 ... company focused on gynecologic disease, announced today that ... Schuler , Birchview Fund LLC and several Vermillion ... of unregistered shares of Vermillion,s common stock and ... stock in a private placement.  ...
(Date:12/22/2014)... The Center for Professional Innovation ... training across the life sciences industry, has partnered with ... to provide the organization's members with discounted classroom courses, ... the more than 350 sessions across 80 course titles. ... when registering for a public course at ...
Breaking Biology Technology:Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3
... NEW YORK, Oct. 16 Wall St. Network,s 3-Minute,Press ... Tracee Tolentino that,features in-depth interviews with public company executives ... show is designed to provide viewers with insight into ... growth., Shows air Monday through ...
... first-cycle,approval for a new molecular entity (NME) is ... average, according to a new analysis from,PAREXEL Consulting, ... PRXL ),and leading global life sciences consultancy serving ... PAREXEL Consulting,analysis, 60 percent of sales for newly-approved ...
... The future of how the world communicates, and ... from the same source: nanotechnology. According to a ... on Emerging Nanotechnologies (PEN), nanotechnology will be central ... "green" energy technologies. , In the latest ...
Cached Biology Technology:[video] Wall St. Network's 3-Minute Press Show Features Executive Interviews and Highlights Recent Press for the Following: IMMU, KYUS 2PAREXEL Consulting Quantifies Speed to Market: First-Cycle Approval for NME Produces $640 Million in Incremental Revenue on Average 2PAREXEL Consulting Quantifies Speed to Market: First-Cycle Approval for NME Produces $640 Million in Incremental Revenue on Average 3PAREXEL Consulting Quantifies Speed to Market: First-Cycle Approval for NME Produces $640 Million in Incremental Revenue on Average 4PAREXEL Consulting Quantifies Speed to Market: First-Cycle Approval for NME Produces $640 Million in Incremental Revenue on Average 5
Protein YIPF6 (YIP1 family member 6). [Source:Uniprot/SWISSPROT;Acc:Q96EC8] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Bovine Calf Serum...
... is designed to deparaffinize and perform Heat ... paraffin-embedded tissue sections mounted on glass microscope ... paraffin at the high temperature used in ... of the paraffin by detergent. Formaldehyde fixation ...
Chicken polyclonal to ytzF ( Abpromise for all tested applications). Antigen: Full length protein...
Biology Products: