Navigation Links
Increased sensitivity to nerve signals keeps diabetes at bay

/p>

Food intake is known to trigger an increase in parasympathetic nerve impulses involving signals of different origins that are integrated in the brain, the researchers said. In the pancreas, parasympathetic nerve endings release the messenger acetylcholine before and most likely after food is absorbed.

"However, the importance of parasympathetic innervation of pancreatic beta cells in maintaining normal glucose balance had remained controversial," Wess said. "Much of this controversy has arisen because peripheral parasympathetic nerves release at least five different neurotransmitters, and increased parasympathetic outflow affects the function of many organs and tissues that have important metabolic functions."

The researchers overcame those difficulties in the current study by examining the glucose tolerance and insulin release of otherwise normal mice that were deficient for M3 receptors only in pancreatic beta cells, and in mice that contained an increased number of M3 receptors specifically in beta cells.

"We've established an important role for the native M3 receptor in beta cells in maintaining normal insulin release and blood glucose levels," Wess said. "It's also clear from our findings that the parasympathetic nervous system's modulation of blood sugar is not a transient event--its effects on the pancreas are sustained for a long time after a meal."


'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
2. Increased risk of osteoporosis associated with gene that one in five people have
3. WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
4. Childrens taste sensitivity and food choices influenced by taste gene
5. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
6. Assessing the Amazon Rivers sensitivity to deforestation
7. Global warming increases oyster sensitivity to pollution
8. Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs
9. Clock molecules sensitivity to lithium sheds light on bipolar disorder
10. With record resolution and sensitivity, tool images how life organizes in a cell membrane
11. Restoring tamoxifen sensitivity in resistant breast cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Increased sensitivity nerve signals keeps diabetes bay

(Date:6/17/2015)... HILDEN, Germany , June 17, 2015 /PRNewswire/ ... Prime Standard: QIA) today launched new Investigator ® STR ... in the United States . The new ... multiple key genomic markers (short tandem repeats or STRs) for ... to evaluate the quality of DNA in each sample, a ...
(Date:6/17/2015)... PALM BEACH GARDENS, Fla. , June 17, ... identity management solutions, today announced that its U.are.U ... by Togo,s Eateries, Inc., ... based fast casual sandwich chain, to increase security, ... (POS). The Crossmatch fingerprint readers enable instant, non-repudiable identity ...
(Date:6/16/2015)... YORK , June 16, 2015  With the ... world, security remains a top concern. The recent compromise ... confirms the need for strong authentication within government agencies. ... Token, a biometric one-time password (OTP) authenticator, has been ... Standards (FIPS) 140-2 Level 3 validation for tamper proofing. ...
Breaking Biology News(10 mins):QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5Togo's Eateries Improve Security and Accountability with Crossmatch Fingerprint Readers 2Togo's Eateries Improve Security and Accountability with Crossmatch Fingerprint Readers 3Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 2Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 3
... Jewish Health and four other research centers have been ... Heart Lung and Blood Institute as part of the ... national scientists to delve deeply into the biology of ... therapeutic options. The multi-center Lung Genomics Research Consortium will ...
... CITY, Calif., Oct. 7 DigitalPersona, Inc., a ... announced that Panasonic System Solutions Company is now ... field-upgradeable option on Panasonic,s modular point-of-sale (POS) workstation, ... a modular case that can be attached to ...
... degradation in dryland regions continuing to worsen, the ... scientist-recommended indicators for monitoring and assessing desertification that ... agreement was reached after two weeks of negotiations ... the Ninth Session of the Conference of the ...
Cached Biology News:NHLBI awards $11 million for molecular roadmap to chronic lung diseases 2Panasonic Offers U.are.U(R) Fingerprint Sensor From DigitalPersona on Stingray JS-950 Point-of-Sale Workstations 2Satellite data instrumental in combating desertification 2Satellite data instrumental in combating desertification 3
(Date:7/7/2015)... Pensacola, FL (PRWEB) , ... July 07, 2015 ... ... trials, ActiGraph’s CentrePoint Study Admin system was developed to solve many ... collection and analysis, particularly within studies that involve multiple clinical sites and/or remote ...
(Date:7/6/2015)... ... 06, 2015 , ... Proove Biosciences , a commercial ... Medical Advisory Board meeting in Palm Springs, California. At the bi-annual meeting, the ... discuss new clinical practice and research ideas. The Board also discussed the development ...
(Date:7/6/2015)... , June 29, 2015 ... has announced the addition of the "Biotechnology ... Biotechnology for the Non-Biotechnologist, ideal for ... theory, principles, techniques and potential of biotechnology. ... understand the basic theory, principles, techniques, and potential ...
(Date:7/5/2015)... ... July 06, 2015 , ... For many years, metal-on-quartz ... had a high-end machine such as a Varian Cary 4000-7000, a Perkin Elmer 800-1100 ... this design that even NIST used them for their SRM-2031 series going back for ...
Breaking Biology Technology:ActiGraph Launches CentrePoint Cloud-based Study Management Software Platform 2ActiGraph Launches CentrePoint Cloud-based Study Management Software Platform 3Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 2Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 3FireflySci Simplifies the Calibration of UV Spectrophotometers with FUV Photometric Accuracy Standards 2FireflySci Simplifies the Calibration of UV Spectrophotometers with FUV Photometric Accuracy Standards 3
... GENEVA , February 3 Viroblock SA, ... products, today,announced that Dr. Jamie Paterson will join Viroblock ... Paterson , a British national, can look back at 20 years ... Commercial Officer at Neurim Pharmaceuticals. During his 18 years at,Procter & ...
... This release is available in German . ... A white light appears out of nowhere. And a light ... upon close examination does the source of the apparently supernatural ... passes through thousands of infinitesimal lens structures measuring only a ...
... ... drug development community thanks to their complexity and substantial potential benefits for sponsors and patients. ... Inc. discusses the rapid evolution of the adaptive trial model and the latest thinking about ... ...
Cached Biology Technology:Viroblock SA Hires Dr. Jamie Paterson as CEO and Closes Financing Round 2Nano for the senses 2Nano for the senses 3Adaptive Trial Paper Explores Benefits of Adaptive Trials for Phase I, Phase II Studies 2Adaptive Trial Paper Explores Benefits of Adaptive Trials for Phase I, Phase II Studies 3Adaptive Trial Paper Explores Benefits of Adaptive Trials for Phase I, Phase II Studies 4
... Preparation contains a unique β-agarose digesting enzyme ... of intact DNA and RNA from low ... in TAE, TBE, MOPS, or phosphate buffers. ... the TAE, TBE, MOPS, and phosphate electrophoresis ...
Request Info...
... new Thermo Electron RapidStak provides valuable walk-away ... a unique buffer nest technology for parallel ... RapidStak provides fast, reliable automation for any ... walk-away confidence. The RapidStak can be set-up ...
... genetically engineered endonuclease. This unique enzyme degrades ... having no proteolytic activity. It is effective ... possesses an exceptionally high specific activity. Ideal ... proteins, its use enables compliance with FDA ...
Biology Products: