Navigation Links
Incidence of stroke decreases over last 50 years

The incidence of stroke in the U.S. over the past 50 years has declined, although the severity of stroke has not, according to a study in the December 27 issue of JAMA.

Stroke continues to be a major public health concern, with more than 750,000 new strokes occurring each year in the United States. It is the third leading cause of death behind heart disease and cancer and the leading neurologic cause of long-term disability, according to background information in the article. Prior estimates of long-term trends in the incidence and severity of stroke have varied. Determining trends could help guide health programs, public policy, and the allocation of research funding.

Raphael Carandang, M.D., of Boston University, and colleagues examined data from the Framingham Study (health study, with participants initially recruited in 1948) to determine long-term trends in the incidence, lifetime risk, severity, and 30-day risk of death from clinical stroke. This study included 9,152 Framingham Study original participants and offspring undergoing follow-up for up to 50 years over three consecutive time-periods (1950-1977, 1978-1989, and 1990-2004), with ascertainment of stroke risk factor data every 2 years and active surveillance for occurrence of stroke or death.

The researchers found that the age-adjusted annual incidence of clinical stroke and atherothrombotic brain infarctions (ABI) in participants age 55 to 94 years decreased over the 3 periods. The incidence of clinical stroke decreased significantly. Across the 3 periods, the lifetime risk of clinical stroke (by age 90 years) decreased from 19.5 percent to 14.5 percent in men age 65 years and from 18.0 percent to 16.1 percent in women. Age-adjusted stroke severity did not vary across periods; however, death within 30 days of stroke decreased significantly in men (from 23 percent to 14 percent) but not significantly in women (from 21 percent to 20 percent).

"The severity of stroke has not decreased and 30-day mortality has decreased significantly only in men, perhaps due to an older age at onset of stroke and more severe strokes in women. These sobering trends emphasize that while improved control of risk factors has lowered incidence of stroke, there is a need for greater primary prevention efforts to reduce the lifetime risk, severity, and 30-day mortality following stroke," the authors conclude.


Source:JAMA and Archives Journals

Related biology news :

1. Researchers discover molecule that causes secondary stroke
2. Molecular cabal contributes to stroke damage
3. Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
4. Limiting the damage in stroke
5. Cord blood cells may widen treatment window for stroke
6. Bad enzymes may wear white hats after stroke
7. Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
8. Internal body clock dictates timing of different types of stroke
9. New compound reduces stroke damage
10. Acidity in the brain could hold the key to stroke treatment
11. UBC researchers find stroke death channel
Post Your Comments:

(Date:11/11/2015)...   MedNet Solutions , an innovative SaaS-based eClinical technology ... pleased to announce that it will be a Sponsor of ... to be held November 17-19 in Hamburg ... of iMedNet , MedNet,s easy-to-use, proven and ... has been able to deliver time and cost savings of ...
(Date:11/10/2015)... YORK , Nov. 10, 2015 ... to behavioral biometrics that helps to identify and ... fraud. Signature is considered as the secure and ... the identification of a particular individual because each ... more accurate results especially when dynamic signature of ...
(Date:11/9/2015)... 9, 2015  Synaptics Inc. (NASDAQ: SYNA ), ... broader entry into the automotive market with a comprehensive ... pace of consumer electronics human interface innovation. Synaptics, industry-leading ... for the automotive industry and will be implemented in ... Europe , Japan , and ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) today announced ... 29, 2015 at 11:00 a.m. Israel time, at ... 98 Yigal Allon Street, 36 th Floor, Tel Aviv, ... Eric Paneth and Izhak Tamir to the Board of ... as external directors; , approval of an amendment to certain terms ...
(Date:11/24/2015)... Nov. 24, 2015  Twist Bioscience, a company ... Leproust, Ph.D., Twist Bioscience chief executive officer, will ... on December 1, 2015 at 3:10 p.m. Eastern ... City. --> --> ... Twist Bioscience is on Twitter. Sign up to ...
(Date:11/24/2015)... , ... November 24, 2015 , ... InSphero AG, the ... cell culture models, has promoted Melanie Aregger to serve as Chief Operating Officer. ... served on the management team and was promoted to Head of InSphero ...
(Date:11/24/2015)... QC , Nov. 24, 2015 /CNW Telbec/ - ProMetic ... "Corporation") announced today that Mr. Pierre Laurin , President ... corporate presentation at the upcoming Piper Jaffray 27 th ... Palace Hotel, on December 1-2, 2015. st ... available for one-on-one meetings throughout the day. The presentation will ...
Breaking Biology Technology: