Navigation Links
Improving outcomes in premature births

The costs due to complications from preterm birth are staggering. In Canada, outlays for specialized care of surviving preterm infants are estimated to be almost $2 billion per year. In a 5-year, randomized, placebo-controlled clinical study, researchers found that giving nitroglycerin to mothers who had entered premature labor led to significant improvement in their baby’s health. The results of the study are reported in the January issue of the American Journal of Obstetrics & Gynecology.

In previous studies of drugs to suppress labor contractions to allow the fetus more time to develop in utero, some drugs were able to delay delivery, but none improved the baby’s health outcome. This study is the first to show that the baby benefited from the therapy, especially those who are born very prematurely (at 24 to 28 weeks). Using a composite measure of the newborn’s health including perinatal death, markers of brain damage and serious lung and bowel complications, mothers treated with nitroglycerin had significantly healthier babies.

Graeme N. Smith, MD, PhD, states, "Our team is very excited about these findings. It is estimated that it costs the Canadian health system almost $2 billion a year to take care of premature babies and their medical complications. Given the immeasurable societal and family costs associated with preterm birth and having a sick baby or child, treatment with nitroglycerin may result in major cost saving and longer-term health benefits for these babies."

In an accompanying editorial, Associate Editor Jay D. Iams, MD, writes about the study, "Their work is notable not only for their interesting results but also for the quality of the study design, execution, and report." He continues, "Perhaps most importantly, the authors chose neonatal morbidity, a ‘health outcome,?as the primary endpoint instead of a surrogate such as days gained or percent of births before 32 or 35 weeks of gestation."
'"/>

Source:Elsevier Health Sciences


Page: 1

Related biology news :

1. Improving the potential of cancer vaccines
2. Predicting successful outcomes in living-donor liver transplants
3. Signature of chromosome instability predicts cancer outcomes
4. Gene signature assesses breast cancer outcomes
5. Anti-cancer drugs may hold promise for premature aging disorder
6. Most embryos produced during IVF do not result in live births
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... and ITHACA, N.Y. , June ... Cornell University, a leader in dairy research, today announced ... designed to help reduce the chances that the global ... onset of this dairy project, Cornell University has become ... Sequencing the Food Supply Chain, a food safety initiative ...
(Date:5/6/2017)... May 5, 2017 RAM Group ... a new breakthrough in biometric authentication based on ... mechanical properties to perform biometric authentication. These new sensors ... material created by Ram Group and its partners. This ... transportation, supply chains and security. Ram Group is ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced ... will feature emerging and evolving technology through ... Innovation Summits will run alongside the expo portion of ... sessions, panels and demonstrations focused on trending topics within ... advanced design and manufacturing event will take place June ...
Breaking Biology News(10 mins):
(Date:7/16/2017)... (PRWEB) , ... July 16, 2017 , ... ... equipment and analytical instruments announced the launch of its new line of Rocking ... five rocking and waving shaker models (both analog and digital) for laboratory applications ...
(Date:7/14/2017)... ... July 14, 2017 , ... Sonic Manufacturing Technologies ... Technologies has installed a solar system on its roof top. “We will be ... of Sonic, Kenneth Raab stated. The company’s proud history of social responsibility and ...
(Date:7/14/2017)... Denville, USA/ Martinsried, Germany (PRWEB) , ... July ... ... a newly developed standardized solution for sample preparation of proteins to clean peptides ... the Diagenode Bioruptor® sonication system. , The PreOmics iST Kit is based ...
(Date:7/13/2017)... (PRWEB) , ... July 13, 2017 , ... ... of surgical instruments in Orthopedics, has announced today the completion of a major ... shareholder to drive organic and external growth. The alliance fuels In’Tech Medical’s service ...
Breaking Biology Technology: