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Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

Improved Outcomes Software (IOS) today announced the release of GeneLinker(TM) Gold and Platinum 4.6, new versions of the award-winning Gene Expression and Proteomics Analysis Software products. "The new releases are focused primarily on importing and analyzing protein biomarker data, a high priority for many of our customers. For example, we have integrated the Protein Biomarker Package into the latest versions of the products (previously the Protein Biomarker Package required a separate installation). We have also provided improved Proteomics Import Scripts and enabled the import of p-value spectrum data to allow exported p-values from ANOVA experiments to be re-imported, enabling novel visualization of channels that best distinguish between different classes (see Protein Biomarker/Proteomics Examples available on the website)" said Dr. Tom Radcliffe, Chief Scientific Officer of IOS.

"The feature set required for microarray analysis is becoming more mature so we have been concentrating more on proteomics data recently. For example Silicon Genetics new GeneSpring?7 includes Support Vector Machines (SVMs). SVMs have been available in GeneLinker Platinum for more than a year and a half. GeneLinker's committee of learners architecture (still not available in GeneSpring?7) provides significant advantages by preventing over-training and reducing the effect of bad samples by requiring consensus among multiple learners to make predictions." said Mark Chatterley, VP Bioinformatics at IOS. "Despite our new focus, we are still enhancing our products for gene expression data analysis. We've added additional data import scripts to handle Koadarray ratio and two-color data (including confidence values). Koadarray is very easy to use and produces better results than other leading array image analysis software programs." added VP Bioinformatics Mark Chatterley. IOS and Koada Technology will also soon be announcing details of co-marketing discount offers on GeneLinker and Koadarray. Further information about Koadarray image analysis software and a free evaluation download can be found at The main features in both Platinum 4.6 and Gold 4.6 that differentiate them from the previous versions are: - Addition of Improved Outcomes' Protein Biomarker Package that previously required a separate installation. - Improved Proteomics Import Scripts for use with the new NIH/NCI Center for Cancer Research Ovarian dataset 8-7-02 (see Protein Biomarker/Proteomics Examples available at for more details). - New “Import P-Value Spectrum?script creates a dataset from the p-values and false-discovery rate. This allows exported p-values from ANOVA experiments to be re-imported, enabling novel visualization of channels that best distinguish between different classes (see Protein Biomarker/Proteomics Examples available at for more details). - Additional data import scripts to handle Koadarray ratio and two-color data (including confidence values). This is also the first release of GeneLinker by Improved Outcomes Software Inc. (following Predictive Patterns Software Inc.'s merger with Visible Bytes Software Inc.). GeneLinker Gold is the entry level product that is well suited to researchers just entering the area of genomics or proteomics research, while GeneLinker Platinum offers powerful feature detection, committees of neural networks, committees of SVMs and committees of Bayesian classifiers that are more suitable to the intermediate or advanced researcher. "This new release illustrates our commitment to supporting and advancing the GeneLinker products. The feature sets in either product cannot be matched by any of our competitors at their respective price points," said Radcliffe. "It also demonstrates our commitment to serving user needs--analysis of protein biomarker data, identifying channels that statistically distinguish between different classes and new imp ort formats were the most frequent user-requested features, and we have responded to those requests." Improved Outcomes Software Inc. was formed by the merger of Predictive Patterns Software Inc. and Visible Bytes Software Inc. in January of 2004. The company provides development, project management and data analysis services in the bioinformatics, image guided surgery and IT industries and also sells software products. Their target customer for the GeneLinker products is the front-line investigator who has data and needs a powerful, intuitive tool to analyze it.


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