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Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory

use in assisted conception treatments. This is a long way off and we would have to prove it was safe because, for example, the culture process may cause genetic changes. For some men and women this would be the only route for producing sperm and eggs. It would not be reproductive cloning as fertilisation would involve only one set of gametes produced in this way and therefore a unique embryo would form.

"In addition, if we could produce eggs from HESCs they could also be used for therapeutic cloning (somatic nuclear replacement) circumventing the need for eggs from patients who donate them, as this is a major limitation of this technique at the moment. We would then have completed the circle of making HESCs from eggs that came from HESCs ?what came first the chicken or the egg?!"


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Source:European Society for Human Reproduction and Embryology


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