Navigation Links
Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory

Scientists in the UK have proved that human embryonic stem cells can develop in the laboratory into the early forms of cells that eventually become eggs or sperm. Their work opens up the possibility that eggs and sperm could be grown from stem cells and used for assisted reproduction, therapeutic cloning and the creation of more stem cells for further research and for the improved treatments for patients suffering from a range of diseases.

Behrouz Aflatoonian will tell the 21st annual conference of the European Society of Human Reproduction and Embryology today (Monday 20 June) that the research also solves the practical and ethical problems associated with obtaining human samples of primordial germ cells (PGCs), which are the ancestral cells that eventually form eggs and sperm (gametes). "Investigating the mechanisms of human primordial germ cell and gamete development is important for understanding the causes of infertility and the potential harmful effects of environmental chemicals on reproductive development," he will say. "But at present it is very difficult to obtain human samples of these cells as they only occur early in development."

Mr Aflatoonian, who is a PhD student in Professor Harry Moore's laboratory at the Centre for Stem Cell Biology, University of Sheffield, UK, said that studies with mice embryonic stem cells had shown that they were capable of differentiating into PGCs and subsequently eggs and sperm, so he set out to see if the same applied to human embryonic stem cells (HESCs).

"We derived six embryonic stem cell lines from embryos donated for research under HFEA regulations by couples undergoing IVF treatment. In addition, we utilised cell lines from the University of Wisconsin.

"The human embryonic stem cells were allowed to develop into collections of cells called embryoid bodies. The embryoid bodies were tested to see which genes were active, or 'expressed', in them and it was found that within two weeks a v
'"/>

Source:European Society for Human Reproduction and Embryology


Page: 1 2 3

Related biology news :

1. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
2. New Clues Add 40,000 Years to Age of Human Species
3. Human Cells Filmed Instantly Messaging for First Time
4. Govt Creates Gene Database of Normal Human Tissues
5. Analysis Of Human Genome To Predict The Development Of Illnesses
6. Human Eggs Can Develop From Ovarian Surface Cells In Vitro
7. Determining The Fate Of Cells In The Human Body
8. Whole genome promoter mapping - Human Genome Project v2.0?
9. Going To Extremes To Improve Human Health
10. Human brain is still evolving
11. Human cerebellum and cortex age in very different ways
Post Your Comments:
(Date:8/12/2015)... , Aug. 12, 2015   MedNet Solutions ... the entire spectrum of clinical research, is proud to ... the company,s comprehensive SaaS-based eClinical technology platform, has led ... the first two quarters of 2015.   Q2 2015 ... largest quarters measured by contract value sold in the ...
(Date:8/10/2015)... BOSTON and TELTOW, Germany ... SensoMotoric Instruments (SMI), a world leader in Eye ... the completion of its OEM Eye Tracking Platform for ... Eye Tracking Platform contains reference designs for seamless integration ... kiosk systems, virtual reality HMDs and augmented reality smart ...
(Date:8/5/2015)... , August 5, 2015 According ... Access Management Market by Software, Services, Vertical (BFSI, Airport, IT ... Geography - Global Forecast to 2020", published by MarketsandMarkets, ... Market globally into various segments. The global PIAM Market ... to $546.2 Million by 2019, at a CAGR of ...
Breaking Biology News(10 mins):MedNet Solutions Experiences Explosive Corporate Growth 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4
... acetyl CoA carboxylase 2,or ACC2, appears to turn the ... in part why the animals can eat more and ... Medicine,researchers.,The report that appears online today in the Proceedings ... cells in these mice bred to lack ACC2," said ...
... University,of California, San Diego have invented a process ... of specialized cells being sought as possible,treatments for ... and Shu Chien, UCSD bioengineering professors, and Christopher,J. ... in a paper published in the February issue ...
... have discovered a way to overcome one of the ... kill normal cells in the,process of eradicating cancer cells.,In ... of the Proceedings of the,National Academy of Sciences (PNAS), ... into a specially designed,virus. The virus eradicated prostate cancer ...
Cached Biology News:Lack of enzyme turns fat cells into fat burners 2Priming embryonic stem cells to fulfill their promise 2Priming embryonic stem cells to fulfill their promise 3Columbia research lifts major hurdle to gene therapy for cancer 2
(Date:9/1/2015)... The Dohmen Company today announced the ... as Chief Science Officer (CSO) of Dohmen Life ... Dr. Floyd will lead Dohmen,s growing regulatory consulting ... and post approval outsourced services in quality, regulatory, ... Floyd brings decades of experience leading global regulatory ...
(Date:9/1/2015)... , Sept. 1, 2015   Medfusion, Inc., ... the relationship between doctors and patients, today announced ... Durham, N.C. -based venture capital firms.   ... business association with Bull City Venture Partners and ... Medfusion Founder and Executive Chairman. "Both firms, experience ...
(Date:9/1/2015)... ... 2015 , ... Research conducted by Synedgen Inc.’s Director for ... of Medicine, Frederick National Laboratory for Cancer Research, and the Centers for Disease ... journal. , Christopher Ryan PhD, of Synedgen, and Aparajita Chatterjee, Daniel M. ...
(Date:8/31/2015)... Calif. (PRWEB) , ... August 31, 2015 , ... ... this year to bring together supply chain risk management and resiliency practitioners with ... develop and share best practices, and be recognized for their innovations and performance ...
Breaking Biology Technology:Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 2Dohmen Life Science Services Appoints Eric Floyd, Ph.D. as Chief Science Officer 3Medfusion Secures Funding to Continue Evolution and Advance Mobile Strategy 2Medfusion Secures Funding to Continue Evolution and Advance Mobile Strategy 3Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 2Synedgen’s Director for Pharmaceutical Manufacturing Publishes New Research 3Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3
... , , , 7.6.4 Long PCR , ... as desired with every temperature , command, enables a , ... , With Long PCR, this function can be used ... elongation. , , ...
... , , , , , ... set of conditions that can be applied to all PCR amplifications. For ... used, the annealing temperatures , of the PCRs can differ ... stringent annealing temperature is a prerequisite for reliable results , ...
... , , , , ... fragment using the PCR* are an everyday occurrence in the lab. For example, , ... which hinder, , or even prevent, further analyses (cycle ... of the PCR result. In such cases, PCR , ...
Cached Biology Technology:PCR Optimization 2PCR Optimization 3Using Gradient PCR to determine the optimum annealing temperature. 2