Navigation Links
How taste response is hard-wired into the brain

Instantly reacting to the sweet lure of chocolate or the bitter taste of strychnine would seem to demand that such behavioral responses be so innate as to be hard-wired into the brain. Indeed, in studies with the easily manipulable fruit fly Drosophila, Kristin Scott and colleagues reported in the January 19, 2006, issue of Neuron experiments demonstrating just such a hard-wired circuitry.

Their findings, they said, favor a model for taste encoding in the brain that holds that specific cells are dedicated to detecting specific tastes. Competing models hold that multiple neurons combine information to encode taste, or that the timing of patterns of taste information encodes taste.

In their studies, the researchers explored the behavioral effects of activating fly taste neurons that had either of two chemical taste receptors on their surface. In earlier studies, the researchers had shown that the Gr5a receptor on taste neurons was essential for response to sugar and that the Gr66a receptor was essential for response to bitter tastes. However, those studies left open the question of whether those different neurons selectively detected the different tastes and whether they generated taste behaviors.

To directly monitor taste responses of the flies, the researchers generated flies with fluorescent labels on their neurons that would signal activation of one or the other type. They used microscopic imaging through tiny windows in the fly brains to watch neuronal response when they exposed the flies to sweet or bitter chemicals

They found that a whole range of sweet substances selectively switched-on the Gr5a neurons, while a range of bitter substances switched-on the Gr66a neurons. However, the "sweet neurons" did not respond to bitter substances, and vice versa.

In behavioral studies, they found that flies preferred to spend time tasting substances that activated the Gr5a neurons and avoided substances that activated Gr66a neurons.<
'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Childrens taste sensitivity and food choices influenced by taste gene
2. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
3. Bad aftertaste? New sensory on/off switch may cure bane of artificial sweetener search
4. Bitter or sweet? The same taste bud can tell the difference
5. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
6. Living taste cells produced outside the body
7. Great (taste) expectations: Study shows brain anticipates taste, shifts gears
8. Sweet water taste paradoxically predicts sweet taste inhibitors
9. Variation in bitter-taste receptor gene increases risk for alcoholism
10. Scientists solve sour taste proteins
11. Tastes great! Study shows brains response to pleasing -- and changing -- tastes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: How taste response hard wired into the brain

(Date:9/16/2014)... Researchers at the Columbia Center for Children,s Environmental Health ... first to demonstrate an association between childhood asthma and ... array of household products. Results appear online in the ... born to mothers exposed during pregnancy to higher levels ... (DnBP) had a 72 percent and 78 percent increase ...
(Date:9/16/2014)... neuroscientists have discovered the "molecular brakes" that time the ... of mice. These "hair cells" translate sound waves into ... are interpreted as sounds. If the arrangement of the ... summary of the research will be published in ... "The proteins Hey1 and Hey2 act as brakes to ...
(Date:9/16/2014)... EUGENE, Ore. -- Each tree species has its own ... researchers and colleagues from other institutions who studied the ... growing on a Panamanian island. , "This study demonstrates ... plant families and with different ecological strategies possess very ... Steven W. Kembel, a former postdoctoral researcher in the ...
Breaking Biology News(10 mins):Phthalates heighten risk for childhood asthma 2Phthalates heighten risk for childhood asthma 3Hey1 and Hey2 ensure inner ear 'hair cells' are made at the right time, in the right place 2Microbiome research shows each tree species has a unique bacterial identity 2
... WEST LAFAYETTE, Ind. - Researchers at Purdue University have ... in spinal cord injuries using nano-spheres that could be ... The synthetic "copolymer micelles" are drug-delivery spheres about 60 ... the diameter of a red blood cell. Researchers ...
... To celebrate the 150th anniversary this month of ... American Institute of Biological Sciences (AIBS) is publishing open ... historic insights into evolution. , The two articles are ... and James T. Costa of Western Carolina University. Padian,s ...
... The National Association of Biology Teachers (NABT) will ... at Naugatuck Valley Community College (NVCC) in Waterbury, ... the NABT annual professional development conference to be ... The Evolution Education Award is cosponsored by the ...
Cached Biology News:Findings show nanomedicine promising for treating spinal cord injuries 2Findings show nanomedicine promising for treating spinal cord injuries 3Biologists, educators recognize excellence in evolution education 2
(Date:9/17/2014)... JH Technologies announces the grand ... JH Technologies, a leader in sales and support ... expanded partnership with Leica Microsystems into the Southern California ... solutions will be featured at the grand opening slated ... facility is located within the JH Technologies office’s at ...
(Date:9/17/2014)... Hussey Copper , a leader in ... copper, announces Gilmour Academy Ice Arena,s conversion of more ... solid touch surface to help protect against bacteria.  MD-Cu ... that kills greater than 99.9% of MRSA, E-coli and ... , Innovative Gilmour Academy ...
(Date:9/17/2014)... 17 de septiembre de 2014  Cryoport, ... proveedor mundial de soluciones logísticas avanzadas criogénicas ... la vida, anunció hoy la contratación de ... con sede en Rótterdam, Países Bajos, para ... Europa en rápido crecimiento. Según los términos ...
(Date:9/17/2014)... 17, 2014 The Pistoia Alliance, ... lowering the barriers to innovation in life sciences ... of Carmen Nitsche as Executive Director Business Development ... its global reach. , Carmen joins the Pistoia ... Corporate Development. At Accelrys, she managed various life ...
Breaking Biology Technology:JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 3Innovative Gilmour Academy Ice Arena changes more than 200 fixtures to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 2Innovative Gilmour Academy Ice Arena changes more than 200 fixtures to Hussey Copper's MD-Cu29 antimicrobial copper to help protect against bacteria 3Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 2Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 3Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 4Cryoport contrata a Broekman Group para mejorar su apoyo operativo y logístico en Europa 5Pistoia Alliance Expands Business Development with Appointment of Carmen Nitsche 2
... Gen-Probe Incorporated (NASDAQ: GPRO ) announced today ... results on Thursday, April 28, 2011 at approximately 4:00 pm ... conference call with management at 4:30 pm ET.   ... be accessed on the investors section of the Company,s web ...
... 14, 2011 /PRNewswire-Asia/ -- Global Pharm Holdings Group, Inc. ... or the "Company"), a Shenzhen-based, leading vertically integrated pharmaceutical ... its subsidiaries in Anhui, Jilin, and Shandong provinces, today ... 31, 2010. Fiscal Year 2010 Highlights ...
... TRIANGLE PARK, N.C., April 14, 2011 Talecris Biotherapeutics Holdings ... quarter earnings release after the market closes on April 27, ... will not be hosting a conference call to discuss its ... Inspiration. Dedication. Innovation. Talecris ...
Cached Biology Technology:Gen-Probe Announces Webcast of First Quarter 2011 Earnings Conference Call 2Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 2Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 3Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 4Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 5Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 6Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 7Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 8Global Pharm Holdings Group Announces Fiscal Year 2010 Financial Results 9
...
Anti-Wnt-2 Polyclonal Antibody Description: 100 g purified goat polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blot/IP/IHC. Research Focus: signal transduction Storage...
... custom microplate coating using advanced automated high throughput microplate processing ... We can also accommodate virtually any lot size of the ... , 8 and 12 well ... 384 well microplate, ...
...
Biology Products: