Navigation Links
How taste response is hard-wired into the brain

Instantly reacting to the sweet lure of chocolate or the bitter taste of strychnine would seem to demand that such behavioral responses be so innate as to be hard-wired into the brain. Indeed, in studies with the easily manipulable fruit fly Drosophila, Kristin Scott and colleagues reported in the January 19, 2006, issue of Neuron experiments demonstrating just such a hard-wired circuitry.

Their findings, they said, favor a model for taste encoding in the brain that holds that specific cells are dedicated to detecting specific tastes. Competing models hold that multiple neurons combine information to encode taste, or that the timing of patterns of taste information encodes taste.

In their studies, the researchers explored the behavioral effects of activating fly taste neurons that had either of two chemical taste receptors on their surface. In earlier studies, the researchers had shown that the Gr5a receptor on taste neurons was essential for response to sugar and that the Gr66a receptor was essential for response to bitter tastes. However, those studies left open the question of whether those different neurons selectively detected the different tastes and whether they generated taste behaviors.

To directly monitor taste responses of the flies, the researchers generated flies with fluorescent labels on their neurons that would signal activation of one or the other type. They used microscopic imaging through tiny windows in the fly brains to watch neuronal response when they exposed the flies to sweet or bitter chemicals

They found that a whole range of sweet substances selectively switched-on the Gr5a neurons, while a range of bitter substances switched-on the Gr66a neurons. However, the "sweet neurons" did not respond to bitter substances, and vice versa.

In behavioral studies, they found that flies preferred to spend time tasting substances that activated the Gr5a neurons and avoided substances that activated Gr66a neurons.<
'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Childrens taste sensitivity and food choices influenced by taste gene
2. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
3. Bad aftertaste? New sensory on/off switch may cure bane of artificial sweetener search
4. Bitter or sweet? The same taste bud can tell the difference
5. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
6. Living taste cells produced outside the body
7. Great (taste) expectations: Study shows brain anticipates taste, shifts gears
8. Sweet water taste paradoxically predicts sweet taste inhibitors
9. Variation in bitter-taste receptor gene increases risk for alcoholism
10. Scientists solve sour taste proteins
11. Tastes great! Study shows brains response to pleasing -- and changing -- tastes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: How taste response hard wired into the brain

(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal genetics company, ... differences in genetic ancestry of individuals from across ... arrived more than four hundred years ago, the ... for peoples from different continents. This study illuminates how American ...
(Date:12/17/2014)... Dec. 15, 2014  HITLAB SM announced today its ... confirm its adherence to current U.S. Food and Drug ... regulated smart device and smart phone application trials utilizing ... "HITLAB is determined to improve global healthcare ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a technology ... measures the overall facial feature of a person such ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... commercially available mineral waters, the researchers found evidence of ... the water. What,s more, these chemicals are potent in ... in the New Zealand mud snail. These findings, which ... of plastic food packaging materials act as functional estrogens, ...
... diseases that can travel with the wind have the ... understood, according to a new study, in findings that ... but also a new fungus that threatens global wheat ... State University and other institutions, concluded that invading diseases ...
... is available in Spanish . , ... of psychosis and schizophrenia, and those episodes of psychosis ... characteristics, both before their appearance and in the clinical ... conclusions of the doctoral thesis "Neurodevelopment and environmental stress ...
Cached Biology News:Hormone-mimics in plastic water bottles -- just the tip of the iceberg? 2New wheat disease could spread faster than expected 2New wheat disease could spread faster than expected 3Daily consumption of cannabis predisposes to the appearance of psychosis and schizophrenia 2
(Date:1/22/2015)... Jersey , 22 de enero de 2015  El Dr. ... hoy su llamada a nominaciones para 2015. Este prestigioso ... hecho, o tiene el potencial para hacer, contribuciones destacadas ... se aceptarán hasta el 15 de marzo de 2015 ...
(Date:12/25/2014)... 25, 2014 The report “Service Quality ... Type &amp; Provider Type - Global Advancements, Worldwide Forecasts ... an in-depth analysis and forecasting of revenues. , ... 221 pages and in-depth TOC on “Service Quality Management ...
(Date:12/24/2014)... December 23, 2014 “Preparative & ... HPLC, Flash), Consumables (Columns, Solvents, Buffers, Valves, Guages, ... & Agriculture) - Forecasts to 2019” provides a ... opportunities, current market trends, and strategies impacting the ...
(Date:12/24/2014)... 23, 2014 According to Ross Selinger, President ... of ITRA Global, the national office market continues to be ... This is evidenced by the third quarter’s surprising 3.9% GDP, ... Low energy costs have held inflation down and the Fed ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3
... , ( NYSE Alternext US: CVM ... ended September 30, 2008.CEL-SCI reported a net loss for fiscal year ... year 2007. The loss per share per common share for ... common share in fiscal year 2007 of $(0.10). Included in the ...
... the Boston Atrial,Fibrillation Symposium, Stereotaxis, Inc. (Nasdaq: ... magnetic ablation that it believes will enhance the,efficiency, ... In booth #917, Stereotaxis will exhibit its ... System for enhanced remote,catheter control and improved EP ...
... meetings held in association,with the JP Morgan Healthcare Conference ... CTIC) reviewed 2009 targeted milestones and 2008,accomplishments. CTI is ... in,addition to potential label expansion for Zevalin(R). In November ... for Zevalin. , "With a ...
Cached Biology Technology:CEL-SCI Corporation Announces 2008 Financial Results 2CEL-SCI Corporation Announces 2008 Financial Results 3Stereotaxis Showcases Advancements for Remote Magnetic Ablations 2Stereotaxis Showcases Advancements for Remote Magnetic Ablations 3Stereotaxis Showcases Advancements for Remote Magnetic Ablations 4Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009 2Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009 3Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009 4Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009 5Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009 6
Umbilical cord blood basophils, For immunohistochemistry (IHC)...
Human peripheral blood CD8+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood PBMC and T Cells...
Umbilical cord blood CD4+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Human peripheral blood CD14+ monocytes, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Monocytes, B Cells, NK Cells and Stem Cells...
Biology Products: