Navigation Links
How nice, brown rice: Study shows rice bran lowers blood pressure in rats

Thousands of years ago, humans began scrubbing off and discarding the outer layer of long-grain rice, preferring the polished white kernel beneath. Now, for the first time, scientists in Japan have shown that this waste product of rice processing, called rice bran, significantly lowers blood pressure in rats whose hypertension resembles that of humans.

The team reports their findings in the March 8 issue of the Journal of Agricultural and Food Chemistry, published by the American Chemical Society, the world’s largest scientific society.

A commonly prescribed class of drugs called ACE inhibitors dilates the arteries of hypertensive patients and thus decreases their risk of stroke, heart attack and kidney disease. But the drugs can also carry side effects: chronic cough, allergic reactions, dizziness, even kidney problems.

What if some component of our diet could work in similar fashion, with few or no side effects? Researchers at Tohoku University and Japan’s National Research Institute of Brewing demonstrated that adding rice bran to the diets of hypertensive, stroke-prone rats lowered the animals?systolic blood pressure by about 20 percent and, via the same mechanism, inhibited angiotensin-1 converting enzyme, or ACE.

“There’s much work being done on various bran fractions to nail down any health benefits,?says the journal’s editor, James Seiber, Ph.D., who is also director of the U.S. Department of Agriculture’s Western Regional Research Center in Davis, Calif. “This particular paper caught my attention for two reasons: the potential of bringing a waste product like rice bran into beneficial use, and the way the group went about their study with good controlled experiments using an appropriate model.?/p>

It’s still not clear whether simply eating more brown rice, which retains some of its bran, would reduce the risk of heart disease. However, previous research in humans, as well as animals with high cholesterol, does sug gest that certain fractions of rice bran can lower levels of unhealthy LDL cholesterol.

The Tohoku study adds antihypertensive activity to the picture, along with a host of other biochemical markers that track blood glucose (implicated in diabetes), lipid profile, kidney function and the harmful effects of free radicals.

For example, high levels of a marker called 8-OHdG indicate biological stress and genetic damage due to oxygen-based free radicals. The researchers found that rice bran, which contains various forms of the antioxidant Vitamin E, markedly lowered the rats?levels of the peptide 8-OHdG.

“Oxidative stress plays an important role in the initiation and progression of cardiovascular diseases,?explained lead author Ardiansyah [editor note: name is correct as written, there is no first name], a Ph.D. candidate at the university’s School of Agricultural Science.

He added one more element to the research that is new: using enzymes to clip components of rice bran from its cell walls, rather than extracting a fraction with ethanol. “I think enzymatic treatment will be more suitable for applications if we’d like to use [rice bran as] functional food,?he said.

The researchers?next step is to elucidate the mechanisms by which specific components of rice bran inhibit ACE and lower cholesterol.


'"/>

Source:American Chemical Society


Related biology news :

1. Chemicals in brown algae may protect against skin cancer
2. A more powerful and efficient engine for rice: the C3-C4 challenge
3. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
4. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
5. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
6. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
7. Study Links Ebola Outbreaks To Animal Carcasses
8. Breakthrough Microarray-based Technology for the Study of Cancer
9. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
10. Study finds more than one-third of human genome regulated by RNA
11. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... March 31, 2016  Genomics firm Nabsys has completed ... Barrett Bready , M.D., who returned to the ... original technical leadership team, including Chief Technology Officer, ... Development, Steve Nurnberg and Vice President of Software and ... company. Dr. Bready served as CEO of ...
(Date:3/22/2016)... PUNE, India , March 22, 2016 ... new market research report "Electronic Sensors Market for ... Fingerprint, Proximity, & Others), Application (Communication & ... and Geography - Global Forecast to 2022", ... consumer industry is expected to reach USD ...
(Date:3/18/2016)... --> --> Competitive Landscape Analysis ... Physical infrastructure and Perimeter Surveillance & Detection Systems ... and the continuing migration crisis in the Middle ... led visiongain to publish this unique report, which is crucial ... & security companies in the border security market and the ...
Breaking Biology News(10 mins):
(Date:5/23/2016)... England , May 23, 2016 ... May 25 th at 10:15 a.m. ET before the ... the role genetically engineered mosquitos can play in controlling the ... carrier of the Zika virus.      (Logo: ... engineered male mosquito with a self-limiting gene. Trials in ...
(Date:5/23/2016)... ... May 23, 2016 , ... RoviSys, a leading independent provider ... Ohio, has broken ground on a new building in Holly Springs, NC. With ... new location solidifies a commitment to business in the region. The new facility ...
(Date:5/22/2016)... , ... May 22, 2016 , ... Doctors in Rome ... combating the asbestos cancer, malignant mesothelioma. Surviving Mesothelioma has just posted an article on ... the University of Rome’s Department of Clinical Sciences and Translational Medicine evaluated more than ...
(Date:5/20/2016)... ... May 20, 2016 , ... Kablooe Design, a leading provider ... announced its official 25th anniversary of the business. “We have worked hard to build ... our customers for the privilege and honor of serving their product design and development ...
Breaking Biology Technology: