Navigation Links
How monarch butterflies are wired for navigation

In their extraordinary annual migration from North America to Mexico, monarch butterflies are known to use the angle of polarized sunlight as a celestial guide to help them keep to a straight and true path southward. But details of their navigational machinery have remained a mystery.

Now, researchers, led by Steven Reppert of University of Massachusetts Medical School, Ivo Sauman of the Czech Academy of Sciences and Adriana Briscoe of the University of California at Irvine, have explored the infinitesimal butterfly brain to uncover new insights into that machinery. Their findings show that the same ultraviolet light that has become an anathema to cancer-wary humans is critical for butterfly navigation. Also, the researchers were surprised to discover a key wiring connection between the light-detecting navigation sensors in the butterfly's eye and the creature's circadian clock--a critical link if the butterflies are to compensate for the time of day in using their "sun compass."

The researchers' techniques include molecular analysis of butterfly brain proteins, as well as flight tests in which the scientists manipulated the light reaching their insect subjects and measured the navigational response.

In their studies, the researchers discovered that ultraviolet photoreceptors dominated in the region of the butterfly visual system known to specialize in polarized light detection. To confirm that the butterflies, indeed, required ultraviolet polarized light to navigate, the researchers tested the insects in a "flight simulator," in which they could control the light polarization and thus influence the butterflies' direction of flight. The researchers found that when they placed a UV-interference filter over the polarized light source, the butterflies lost their orientation response.

The researchers also pinpointed the location of the circadian clock in the butterfly brain. Such circadian clocks govern the approximately 24 hour activity a nd metabolic cycles of animals from the simplest insects to humans. Reppert and his colleagues found that key genes responsible for the clock's molecular "ticks" were expressed in a brain region called the dorsolateral protocerebrum. Using tracer molecules, they were surprised to discover tiny neural fibers containing a key clock protein that connected with the polarization photoreceptors in the butterfly eye.

"This pathway has not been described in any other insect, and it may be a hallmark feature of butterflies that use a time-compensated sun compass," wrote the researchers. They also speculated that another such clock-related pathway of fibers they detected between two regions of the butterfly brain may play a role in regulating the insects' hormonal system, to induce the longevity that enables the butterfly to extend its survival in its overwintering grounds in Mexico.

The researchers include Ivo Sauman of the Czech Academy of Sciences; Adriana D. Briscoe of the University of California, Irvine; Haisun Zhu, Dingding Shi, Quan Yuan, Amy Casselman, and Steven M. Reppert of the University of Massachusetts Medical School; Oren Froy of the University of Massachusetts Medical School (Current Address: The Hebrew University of Jerusalem); and Julia Stalleicken of the University of California, Irvine (Current address: University of Oldenburg). This work was supported in part by grants from the NIH, GAAVCR, NSF and German Academy Exchange Service Grant, as well as the Volkswagenstiftung.

Sauman, I., Briscoe, A.D., Zhu, H., Shi, D., Froy, O., Stalleicken, J., Yuan, Q., Casselman, A., and Reppert, S.M. (2005). Connecting the Navigational Clock to Sun Compass Input in Monarch Butterfly Brain. Neuron 46, 457?67. http://www.neuron.org


'"/>

Source:Cell Press


Related biology news :

1. In the migratory marathon, parasitized monarchs drop out early
2. Expanding forests darken the outlook for butterflies, study shows
3. Female butterflies go for sparkle -- not size -- when choosing to mate
4. Where have all the butterflies gone?
5. Some butterflies travel farther, reproduce faster
6. Male-killing bacteria makes female butterflies more promiscuous
7. The brain is broadly wired for reproduction
8. How taste response is hard-wired into the brain
9. Animal brains hard-wired to recognize predators foot movements, Queens study suggests
10. Is the brain wired for faces?
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... According to a new market research report "Consumer ... Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region - ... to grow from USD 14.30 Billion in 2017 to USD 31.75 Billion ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... , April 11, 2017 No two ... researchers at the New York University Tandon School ... Engineering have found that partial similarities between prints ... used in mobile phones and other electronic devices ... The vulnerability lies in the fact that ...
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... The CRISPR-Cas9 ... overexpression experiments and avoiding the use of exogenous expression plasmids. The simplicity of ... performing systematic gain-of-function studies. , This complement to loss-of-function studies, such as ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia ... be hosting a Webinar titled, “Pathology is going digital. Is your lab ready?” ... pathology adoption best practices and how Proscia improves lab economics and realizes an ...
(Date:10/11/2017)... ... October 11, 2017 , ... Disappearing forests and increased emissions are the ... million people each year. Especially those living in larger cities are affected by air ... one of the most pollution-affected countries globally - decided to take action. , “I ...
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building and cooking events ... announced today. The bold new look is part of a transformation to increase ... a significant growth period. , It will also expand its service offering from its ...
Breaking Biology Technology: