Navigation Links
How fish mend a broken heart

an "elevated regenerative spectrum, with many more tissues capable of impressive regeneration," they said. For instance, certain newts or salamanders can regenerate limbs, spinal cord, retina, brain, and heart tissue.

While progenitor cell populations have been identified within most mammalian organs, including skin, skeletal muscle, brain, and heart, these cells vary widely in frequency and the ability to regenerate damaged or lost tissue, they said. In most mammalian organs, progenitor cells can restore cells lost in the course of normal organ function or after minor injury but cannot regenerate after major damage or removal of structures.

"It is believed that the capacity for regeneration is an ancestral condition that has occasionally been lost in the course of vertebrate evolution." Poss said. "Thus, most biologists suspect that the machinery to optimize regeneration from progenitor cells is present, but lies dormant, in mammals."

In an earlier study, Poss and his colleagues found that zebrafish have a unique ability to regenerate cardiac muscle after major injury. They further suspected that illumination of the fishes' ability might offer important insights into "how heart regeneration is naturally optimized."

In the current study, they found that heart regeneration proceeds through two coordinated stages. First, a mass of undifferentiated, pre-cardiac cells form. Those progenitor cells then begin to differentiate and divide, to replace the damaged heart muscle.

In the second step, the epicardium surrounding the heart chambers "lights up" with activity as developmental genes switch on, Poss said. The epicardium expands to rapidly cover the wounded heart muscle.

A subset of those epicardial cells then alters their identity, invading the wound and providing essential new blood vessels to the growing muscle.

They further found that the two-part regeneration process is coordinated by so-called "fibrob
'"/>

Source:Cell Press


Page: 1 2 3

Related biology news :

1. Single stem cells from bone heal a broken heart
2. Nanotubes inspire new technique for healing broken bones
3. UCLA imaging study of children with autism finds broken mirror neuron system
4. UT Southwestern researchers find gene mutation that leads to broken hearts
5. Tracing broken wiring in stroke patients
6. Global study shows all tobacco bad for the heart
7. New study shows antibiotic may protect the heart
8. Getting to the heart of the heart
9. Slowing the racing heart
10. Hawaiian treasure, macadamia nuts good for the heart
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: How fish mend broken heart

(Date:10/16/2014)... (October 16, 2014) – Post-menopausal women experienced improvements ... hormone levels or genital bleeding, after 12 weeks ... investigational fermented soy germ-based nutritional supplement previously shown ... a new peer-reviewed pilot study reported in a ... annual scientific meeting. , "These data documented ...
(Date:10/15/2014)... German Gauß-Allianz has admitted Johannes Gutenberg University Mainz ... Rhineland-Palatinate science hub continues to maintain a significant ... , "The acceptance of Johannes Gutenberg University ... is a milestone in the national and international ... The state of Rhineland-Palatinate can be proud that ...
(Date:10/15/2014)... VILNIUS, Lithuania , Oct. 15, 2014 /PRNewswire/ ... identification technologies, today announced the availability of the ... . VeriLook Surveillance 3.0 provides real-time biometric face ... multiple high-resolution digital surveillance cameras. The new version ... detects and differentiates people from objects while they ...
Breaking Biology News(10 mins):S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3
... HILO, HawaiiIn collaboration with Stanford University and ... Service Pacific Southwest Research Station,s Institute of Pacific ... developing "hybrid ecosystems"a mix of native and non-native ... in tropical forests. The research team, comprised ...
... parrots and iguanas may seem inoffensive at first glance when ... escape and become invasive species. This has been confirmed by ... 63 Spanish zoos. Birds are the animals most likely to ... (non-indigenous) species, they could become an entry channel for these ...
... -- Specialized white blood cells called T cells and ... and eliminate "non-self" substances such as viruses and bacteria. ... immunoreceptors on the cell surface bind to specific regions on, ... pathways inside the T cells and B cells that control ...
Cached Biology News:US Forest Service and 2 universities team up to develop new ecosystems for Hawaiian forests 275 percent of Spanish zoos at risk of exotic animals escaping 275 percent of Spanish zoos at risk of exotic animals escaping 3
(Date:10/19/2014)... 19, 2014 The Asian Orthopedic braces and ... Asia with analysis and forecast of revenue. The Orthopedic braces ... to around $416.5 million by 2018, at a developing CAGR ... TOC of the Asian Orthopedic braces and support systems market, ... also provides a glimpse of the segmentation of orthopedic braces ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... - Trends and Forecasts to 2019", analyzes the ... in order to understand the industry details such ... opportunities across various geographic regions. , Browse 81 ... 202 Slides and in-depth TOC on “1,6-Hexanediol Market ...
(Date:10/18/2014)... (PRWEB) October 18, 2014 The ... rate in the five years to 2014. The industry's ... renewable energy tax credits that encouraged the use of ... renewable portfolio standards (RPSs), which require local utilities to ... their total energy portfolio. Increased campaigning for green technology ...
(Date:10/17/2014)... Alice,s journey through the looking-glass to Wonderland, mirrors in ... unexpected ways, including a new class of mirror that ... in The Optical Society,s (OSA) new high-impact journal ... first time, a new type of mirror that forgoes ... light by using an unusual magnetic property of a ...
Breaking Biology Technology:The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 2Magnetic mirrors enable new technologies by reflecting light in uncanny ways 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 4
... 21, 2010 Novogen Limited and Marshall Edwards, Inc. ... on the clinical development of novel therapeutics targeting cancer ... definitive asset purchase agreement pursuant to which Marshall Edwards ... for $4 million of convertible preferred stock. ...
... (as well as many members of the public), new ... Scientists from Harvard Medical School, the University of Illinois, ... used genetic analysis to prove that the African savanna ... largely separated for several million years. The researchers, ...
... Dec. 21 2010 El Camino Hospital today announced ... Clinical Trial. El Camino Hospital is one of the ... in the trial, which is evaluating a revolutionary non-surgical, ... for patients with severe aortic stenosis. "The ...
Cached Biology Technology:Novogen and Marshall Edwards Sign Asset Purchase Agreement 2Novogen and Marshall Edwards Sign Asset Purchase Agreement 3Novogen and Marshall Edwards Sign Asset Purchase Agreement 4Novogen and Marshall Edwards Sign Asset Purchase Agreement 5Seeing double: Africa's 2 elephant species 2El Camino Hospital Announces First Implant in Clinical Trial to Evaluate Revolutionary Heart Valve Procedure 2El Camino Hospital Announces First Implant in Clinical Trial to Evaluate Revolutionary Heart Valve Procedure 3
... includes 7 lanes of ... Alzheimer's-diseased brain tissue including: ... frontal lobe, temporal lobe, ... and cerebellum. Patent/trademark/license (electronic): ...
... spatulas have been designed to save time ... those interested in eliminating the recycling and ... is individually packaged, RNase/DNase free, non-pyrogenic and ... new product number, created to easily match ...
... the mechanical harvesting of cells • Blade ... contact with the growth surface • Designed ... • Individually wrapped • Sterilized by gamma ... number is a new product number, created ...
... single use spatulas have been designed to ... are for those interested in eliminating the ... Each spatula is individually packaged, RNase/DNase free, ... is a new product number, created to ...
Biology Products: