Navigation Links
How fish mend a broken heart

an "elevated regenerative spectrum, with many more tissues capable of impressive regeneration," they said. For instance, certain newts or salamanders can regenerate limbs, spinal cord, retina, brain, and heart tissue.

While progenitor cell populations have been identified within most mammalian organs, including skin, skeletal muscle, brain, and heart, these cells vary widely in frequency and the ability to regenerate damaged or lost tissue, they said. In most mammalian organs, progenitor cells can restore cells lost in the course of normal organ function or after minor injury but cannot regenerate after major damage or removal of structures.

"It is believed that the capacity for regeneration is an ancestral condition that has occasionally been lost in the course of vertebrate evolution." Poss said. "Thus, most biologists suspect that the machinery to optimize regeneration from progenitor cells is present, but lies dormant, in mammals."

In an earlier study, Poss and his colleagues found that zebrafish have a unique ability to regenerate cardiac muscle after major injury. They further suspected that illumination of the fishes' ability might offer important insights into "how heart regeneration is naturally optimized."

In the current study, they found that heart regeneration proceeds through two coordinated stages. First, a mass of undifferentiated, pre-cardiac cells form. Those progenitor cells then begin to differentiate and divide, to replace the damaged heart muscle.

In the second step, the epicardium surrounding the heart chambers "lights up" with activity as developmental genes switch on, Poss said. The epicardium expands to rapidly cover the wounded heart muscle.

A subset of those epicardial cells then alters their identity, invading the wound and providing essential new blood vessels to the growing muscle.

They further found that the two-part regeneration process is coordinated by so-called "fibrob
'"/>

Source:Cell Press


Page: 1 2 3

Related biology news :

1. Single stem cells from bone heal a broken heart
2. Nanotubes inspire new technique for healing broken bones
3. UCLA imaging study of children with autism finds broken mirror neuron system
4. UT Southwestern researchers find gene mutation that leads to broken hearts
5. Tracing broken wiring in stroke patients
6. Global study shows all tobacco bad for the heart
7. New study shows antibiotic may protect the heart
8. Getting to the heart of the heart
9. Slowing the racing heart
10. Hawaiian treasure, macadamia nuts good for the heart
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: How fish mend broken heart

(Date:7/25/2014)... molecular testing panel developed at UPMC greatly increases ... for patients with thyroid nodules and cancer, report ... (UPCI), partner with UPMC CancerCenter., The test, available ... diagnostic testing agencies, improved the chances of patients ... according to the study published this month in ...
(Date:7/24/2014)... 2014 -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced ... control Phase 3 study of Zerenex (ferric citrate), the ... treatment of hyperphosphatemia in patients with end-stage renal disease ... iRon delivery with FErric CiTrate in EsrD) was published ... Society of Nephrology ( JASN ). ...
(Date:7/24/2014)... disturbance has different effects on different species of ... Universities of Bristol and Exeter which tested fish ... to a flying seagull predator model when exposed ... in European minnows. , Lead author Dr ... said: "Noise levels in many aquatic environments have ...
Breaking Biology News(10 mins):Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 4
... conditions based on results from the previous day,s sample. Scientists ... lab to culture them for analysis a process that ... engineers from the UCLA Henry Samueli School of Engineering and ... concentrations to under one hour, through the development of a ...
... A new University of Illinois study touts the ... for starterssaying that it reduces the inflammation associated with ... fiber changes the personality of immune cellsthey go from ... help us recover faster from infection," said Gregory Freund, ...
... CAMBRIDGE, Mass., March 2, 2010 Fictional candy maker ... chocolate eggs from bad, an eggucator. Likewise, by determining ... discard, scientists are aiming to find their own golden ... Toward that end, Harvard researchers and a team ...
Cached Biology News:UCLA engineers develop faster method to detect bacterial contamination in coastal waters 2UCLA engineers develop faster method to detect bacterial contamination in coastal waters 3An apple a day? Study shows soluble fiber boosts immune system 2An apple a day? Study shows soluble fiber boosts immune system 3Sorting device for analyzing biological reactions puts the power of a lab in a researcher’s pocket 2Sorting device for analyzing biological reactions puts the power of a lab in a researcher’s pocket 3
(Date:7/24/2014)... -- ECC West Africa, LLC (ECC) signed a contract in ... Hospital (UCH) Ibadan Board of Management for the first ... and operate and maintain a new, state-of-the-art Cancer Institute ... first of the 4-phase project, ECC will conduct feasibility ... Ibadan intends to finance and develop the Cancer Institute ...
(Date:7/24/2014)... have yet to materialise. Yet, scientists are making ... computers faster. One such approach relies on quantum ... applying an electric field. A new study demonstrates ... quantum dots (TQDs) with electrical impulses can help ... should TQDs be used as quantum information units, ...
(Date:7/24/2014)... Research and Markets has announced the addition ... report to their offering.  http://photos.prnewswire.com/prnh/20130307/600769 ... vitro growth of plant or animal cells for several ... Cell culture is a crucial step in tissue engineering ... consumables are necessary for the in vitro production of ...
(Date:7/24/2014)... , July 24, 2014 SRI International ... with the National Institute of Allergy and Infectious Diseases ... conduct preclinical development of potential therapies for HIV infection ... to treat HIV and AIDS and the complications and ... microbicides for preventing sexual transmission of HIV. ...
Breaking Biology Technology:ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2Global Cell Culture Market 2014-2018: Key Vendors are Becton, Dickinson and Co, EMD, GE Healthcare, Lonza Group, Sigma Aldrich and Thermo Fisher Scientific 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... , , , LEXINGTON, Mass. ... holding gmbh announced today the launch of the first human cancer ... targeted Next-Generation Sequencing (NGS). The new catalog cancer biochip features 115 ... of cancer by the Wellcome Trust Sanger Institute. , ...
... , , RARITAN, N.J., July 13 ... can accurately predict the prognosis and survival in patients ... published report in the July 10 issue of the ... retrospective study compared how well CTCs and a more ...
... , SAN MARINO, Calif., July 13 ... compounds for HIV/AIDS, autoimmune diseases, and cancer, has retired the majority ... other debt and recently issued new shares. , ... financing through the issuance of shares. This transaction originally was disclosed ...
Cached Biology Technology:First Catalog Cancer Biochip for Sequence Capture Now Available from febit 2Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 2Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 3Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 4Viral Genetics Retires Nearly $3.5 Million Convertible Debt and Provides Updates on Capital Structure and Stock Issuances 2Viral Genetics Retires Nearly $3.5 Million Convertible Debt and Provides Updates on Capital Structure and Stock Issuances 3
... number is a new product number, created ... showing no availability yet, please order under ... customer service for assistance. ID ... D H 100 20 mm ...
BD BioCoat Gelatin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of gelatin....
Mouse monoclonal antibody raised against a full length recombinant ATF3. NCBI Entrez Gene ID = ATF3...
... Delivers 4,600 to Over 3 Million Genotypes ... is capable of performing 4,600 to over ... the GenomeLab family of products*, this automated, ... 48 SNPs in each well of an ...
Biology Products: