Navigation Links
How exactly does the brain control breathing?

An understanding of exactly how the brain controls breathing is fundamental to the treatment of respiratory disorders. We know that breathing is an automatic rhythmic process that persists without conscious effort whether we are awake or asleep, but the question that has intrigued many scientists for well over 100 years is what maintains this almost fail safe vital rhythm throughout life?

Experimental Physiology editor Julian Paton invited two world renowned scientists Dr. Guyenet from the University of Charlottesville and Dr. Richerson from Yale University, to use the journal as a forum to discuss the issue and attempt to resolve their differences in opinion.

Both authors agree that the respiratory rhythm requires specialised nerve cells (central chemoreceptors) to power the rhythm, but the issue highly debated by Guyenet and Richerson is the precise location and cell types involved. Guyenet proposes that these nerve cells are located in a ventral area of the brainstem (the retrofacial region) and loaded with a transmitter substance called glutamate. Their close proximity to the ventral surface of the brain allows them to sense and react to changes in the pH of the cerebrospinal fluid; this is deemed an essential property of a central chemoreceptor. Richerson, on the other hand, stipulates that central chemoreceptors are found close to the midline blood vessels of the brainstem allowing them to 'taste' the pH of the blood. His cells do not contain glutamate but a substance called serotonin.

Experimental Physiology asked each author to stake out his claim and provide rebuttals and critiques of each others' articles (recently published in Nature Neuroscience).

To view this fascinating exchange of views published in Experimental Physiology-

Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors
Patrice G. Guyenet, Ruth L. Stornetta, Douglas A. Bayliss and Daniel K. Mulkey
Exp Physiol 90
'"/>

Source:Blackwell Publishing Ltd.


Page: 1 2

Related biology news :

1. Controversial drug shown to act on brain protein to cut alcohol use
2. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
3. Mouse brain tumors mimic those in human genetic disorder
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. NYU study reveals how brains immune system fights viral encephalitis
7. Stem cells from brain transformed to produce insulin at Stanford
8. Birds brains reveal source of songs
9. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
10. Revolutionary nanotechnology illuminates brain cells at work
11. A puzzle piece found in unraveling the wiring of the brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: How exactly does the brain control breathing

(Date:9/30/2014)... HEIGHTS, Ill. (September 30, 2014) People who suffer ... can do to control their asthma besides properly taking ... a new article in the Annals of Allergy, ... American College of Allergy, Asthma and Immunology (ACAAI), asthma ... examining their lifestyle. The woman described in the Annals ...
(Date:9/29/2014)... , coupled with a high-fat diet, may cause animals to ... mBio , the online open-access journal of the American Society ... Institute of Human Nutrition Potsdam-Rehbruecke in Nuthetal observed that mice ... weight when fed a high-fat diet. Mice that did not ... consuming a high-fat diet, and mice that had C. ...
(Date:9/29/2014)... -- Plants have a symbiotic relationship with certain ... nutrients and defend against invaders an important ... vegetables. Now, scientist have discovered that plants may ... ensuring that sprouting plants are colonized from the ... Dame, presented their findings today at the 5th ...
Breaking Biology News(10 mins):Asthma symptoms kicking up? Check your exposure to air pollution 2Gut bacteria promote obesity in mice 2Plants prepackage beneficial microbes in their seeds 2
... help transform a key component of disposable cups, ... significantly reducing the environmental impact of this ubiquitous, ... scheduled to appear in the April 1 issue ... Science & Technology . , The microbes, a ...
... Anthropology Jeffrey H. Schwartz and University of Salerno Professor ... New Anatomist journal, shows that the emerging understanding of ... evolution, originally explained in his seminal work, Sudden Origins: ... & Sons, 2000). , In that book, Schwartz hearkens ...
... in less than 0.2% of the 3-billion-base human genome ... human disease. Today, researchers from the Wellcome Trust Sanger ... Research, together with international colleagues report in PLoS Genetics ... well as genes that are unchanged in recent human ...
Cached Biology News:Microbes convert 'Styrofoam? into biodegradable plastic 2Pitt professor's theory of evolution gets boost from cell research 2Pitt professor's theory of evolution gets boost from cell research 3Researchers map of genetic variations implicated in disease 2Researchers map of genetic variations implicated in disease 3
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... trends and segments with highest potential revenues Do ... Visiongain,s updated report gives you revenue predictions for ... ahead. For those therapies you find financial data, ... new analysis you get sales forecasts to 2024 ...
(Date:9/30/2014)... Follow us on LinkedIn ... of cholesterol carrier or lipoprotein in the blood. Such ... levels in the body, especially along the walls of ... and other cardiovascular disorders. Cardiovascular Diseases (CVD) is the ... levels on a regular basis, to assess an individual’s ...
(Date:9/30/2014)... Los Angeles, CA (PRWEB) September 30, 2014 ... Separation (EWS), the high-speed, chemical-free process to clean up ... letter to shareholders, CEO Riggs Eckelberry reported on the ... West Texas, at a site provided by partner ... ramped up to 1000 barrels per day (bpd) and ...
(Date:9/30/2014)... The overall research objective was to ... and use. Most researchers outsource NGS technologies; however, ... within the next 12 months. Data accuracy and ... sequencing instruments. Disease-related research is the dominant use ... to surge, with half of the respondents planning ...
Breaking Biology Technology:Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 4Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 5Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 3Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 4OriginOil, Inc. Report to Shareholders: Blue Gold in West Texas 2Global Next-generation Sequencing Trends 2
... All amounts are in US dollarsQUEBEC CITY, March ... AEZS ; TSX: AEZ), a global biopharmaceutical ... announced the signing of a development, commercialization and ... SNY ) for the development, registration and ...
... as buckyballs may be able to keep the nation,s ... prevent arteries from clogging up. , Engineers at Duke ... bacteria and other microorganisms to accumulate on the membranes ... leads the researchers to believe that coating pipes and ...
... OMAHA, Neb., March 5 Transgenomic, Inc. (OTC ... announced today its Molecular Laboratory has received notification ... offering its services in the state. Transgenomic ... including Mitochondrial Disorders, Oncology and Hematology, Molecular Pathology ...
Cached Biology Technology:AEterna Zentaris and Sanofi-Aventis Sign a Development, Commercialization and Licensing Agreement for Cetrorelix in Benign Prostatic Hyperplasia 2AEterna Zentaris and Sanofi-Aventis Sign a Development, Commercialization and Licensing Agreement for Cetrorelix in Benign Prostatic Hyperplasia 3AEterna Zentaris and Sanofi-Aventis Sign a Development, Commercialization and Licensing Agreement for Cetrorelix in Benign Prostatic Hyperplasia 4AEterna Zentaris and Sanofi-Aventis Sign a Development, Commercialization and Licensing Agreement for Cetrorelix in Benign Prostatic Hyperplasia 5Buckyballs could keep water systems flowing 2Buckyballs could keep water systems flowing 3Transgenomic Awarded Clinical Laboratory Certification in California 2Transgenomic Awarded Clinical Laboratory Certification in California 3
EZ-DeWax is a one-step solution that simultanously removes paraffin from and rehydrates formalin-fixed, paraffin embedded tissue...
MiniCycler thermal cycler with Hot Bonnet heated lid, holds 25x0.2ml tubes...
... Lower operational costs. More efficient ... from limited sample volumes. Industry demands ... to using microbore chromatography for routine ... not adequately satisfy the need to ...
The PDS-1000 He Hepta system includes the PDS-1000 He biolistic system and the Hepta adaptor....
Biology Products: