Navigation Links
Hormones and growth: The control of body size and developmental growth rate in fruit flies

A pair of research papers published this week report findings that increase our understanding of how an organism's body size is determined and how the speed of its development is controlled. In particular, the work sheds light on the molecular and cellular pathways that act to convey information about a growing organism's size, as well as on pathways that use that information to correctly time critical transitional events during development.

The two studies are reported in Current Biology online on September 22 by Dr. Philip E. Caldwell and colleagues of Rice University and Dr. Christen Mirth and colleagues of the University of Washington.

Previous work had shown that there is a close linkage between the final body size of an organism and the length of its developmental stages: Elephants are larger and develop more slowly than mice. However, the mechanisms by which body size and developmental rate are controlled remain incompletely understood.

Both studies examine the control of larval development in the fruit fly Drosophila. Fruit flies undergo three successive larval stages and molts before undergoing metaphorphosis and emerging as adult flies. In insects, it was previously found that the release of the hormone ecdysone from an endocrine organ called the prothoracic gland triggers larval molting and, ultimately, metamorphosis. Thus, researchers have speculated that the timing of ecdysone release is critical in determining both the final body size and developmental rate of an insect.

In their new work, Philip Caldwell, Magdalena Walkiewicz, and Michael Stern manipulated the timing and amount of ecdysone release during development of the fruit fly. They induced precocious ecdysone release by specifically expressing an activated form of the signaling molecule Ras in the endocrine prothoracic gland. This precocious ecdysone release caused flies to develop more rapidly and exhibit a much smaller body size than normal. In contrast, inhibit
'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Ancient olfaction protein is shared by many bugs, offering new pest control target
2. Gene variations explain drug dose required to control seizures
3. U-M scientists find genes that control growth of common skin cancer
4. Scientists discuss improved biopesticides for locust control in West Africa
5. Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
6. To control germs, scientists deploy tiny agents provocateurs
7. Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
8. Master gene controls healing of skin in fruit flies and mammals
9. Remote control flies? Fly behavior controlled by laser light
10. Internet viruses help ecologists control invasive species
11. DNA constraints control structure of attached macromolecules
Post Your Comments:
(Date:8/29/2014)... recently, little has been known about what genetic changes ... of scientists, one of whom is a University of ... that genes controlling the development of the brain and ... The study was published Aug. 28 in Science ... is online at http://www.sciencemag.org/ ., The domestication of ...
(Date:8/29/2014)... German . ... cycle on Earth and in biological wastewater treatment plants. ... on nitrite as their source of energy. An international ... at the University of Vienna, has now shown that ... of energy. The oxidation of hydrogen with oxygen enables ...
(Date:8/29/2014)... twist them, fold them: modern materials that are light, ... as artificial skin or electronic paper. , Making such ... but a new way of working with copper nanowires ... , Previous success in the field of ultra-lightweight ... precious gold and silver nanowires. , By turning ...
Breaking Biology News(10 mins):New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3Copper shines as flexible conductor 2
... University, the team mapped the presence of foxes in ... their likely distribution as a blueprint for fox eradication, ... of Canberra professor in wildlife genetics and leader of ... northern and eastern Tasmania and the model developed by ...
... CA Researchers from the Carnegie Institution are rolling out ... AToMS, for the first time at the American Geophysical ... and its scientific observations are uncovering a previously invisible ... is helping researchers look at the world in a ...
... MA and SAN FRANCISCO, CADecember 4, 2012 The ALS ... today announced the formation of a research collaboration to ... the preclinical drug development process. "We are ... ALS therapeutic development," said Steve Perrin, PhD, CEO and ...
Cached Biology News:Fox invasion threatens wave of extinction, UC research finds 2Carnegie debuts revolutionary biosphere mapping capability at AGU 2Carnegie debuts revolutionary biosphere mapping capability at AGU 3ALS TDI and Gladstone Institutes collaborate to discover potential ALS treatments 2
(Date:8/28/2014)... 2014 Sterlitech is proud to announce ... its stable of products . These additional ... and include membrane filters with surface charges. ... demand for our membrane process testing equipment, and correspondingly, ... sheet membranes,” explains Sterlitech President Mark Spatz. “The ...
(Date:8/28/2014)... TALLAHASSEE, Fla. Exciting new work by a Florida ... molecular system that can take your temperature, emit white ... , And, the molecule looks like a butterfly. , ... and Biomedical Engineering in the FAMU-FSU College of Engineering, ... ago, but has continued to discover that his creation ...
(Date:8/28/2014)... August 28, 2014 A new ... the world is available from Strategic Consulting, Inc., ... “ Industrial Microbiology Market Review, Fourth Edition: Global ... ” (IMMR—4) tracks and compares microbiology test volumes, ... America, Europe and Asia, and forecasts future volumes ...
(Date:8/28/2014)... MA (PRWEB) August 28, 2014 ... wholesale construction materials, selected SoundConnect to ... their cloud based audio and web conferencing platform ... to support PrimeSource’s employees’ needs. SoundConnect delivers ... , PrimeSource Building Products will be utilizing ...
Breaking Biology Technology:Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3PrimeSource Chooses SoundConnect as Collaboration Provider 2
... -- I continue to be encouraged by the numerous ... Midwest. Here are just a few: , ,& bull; The ... 2006. , ,& bull; The continued acquisition of Midwest ... recognize the value of Midwest products and technology, the flip ...
... in Memphis, Tenn., will install a wireless distribution ... organization's corporate office under a $6 million agreement with ... distribution system will provide wireless coverage throughout Baptist's six ... system, which will be installed in the next 12 ...
... a biophysical chemist at the University of Wisconsin-Madison, has ... the Biophysical Society, a 7,000-member U.S. organization that represents ... and biochemistry, Record hopes that the new honor will ... funding for his research. , ,A UW-Madison faculty member ...
Cached Biology Technology:Midwest biotech on a roll 2Midwest biotech on a roll 3Midwest biotech on a roll 4
Mouse monoclonal antibody raised against a partial recombinant CALCOCO2. NCBI Entrez Gene ID = CALCOCO2...
Mouse monoclonal antibody raised against a partial recombinant PRG4. NCBI Entrez Gene ID = PRG4...
Mouse monoclonal to Casein Kinase 2 beta ( Abpromise for all tested applications). entrezGeneID: 1460 SwissProtID: P13862...
... selection system for recombinant identification. Recombinant selection ... need for costly color screening. This quick ... accuracy in recombinant selection. pLivSelect is also ... This cloning kit is customized as ...
Biology Products: