Navigation Links
Hormone linked to brain's cravings for food and other energy sources

Ghrelin, a hormone produced in the stomach, induces food intake and operates through a brain region that controls cravings for food and other energy sources, researchers at Yale School of Medicine report in the October 19 online issue of The Journal of Clinical Investigation.

Ghrelin was previously associated with growth hormone release, appetite, learning, and memory and has now been linked with the reward circuitry of the brain that regulates food cravings.

According to lead author Tamas Horvath, components of the reward circuitry of the ventral tegmental area (VTA), may be responsible for overeating and addiction. "Targeting this region pharmacologically is an interesting tool to explore," said Horvath, chair of the Section of Comparative Medicine at Yale School of Medicine and professor of comparative medicine, neurobiology and obstetrics, gynecology & reproductive sciences.

In this study, Horvath and colleagues found that ghrelin could signal directly in the VTA region and activate dopamine neuronal activity, which controls reward-associated behavior to promote interest in food as a reward. As a default, ghrelin's action may also alter seeking of drugs and substances that work through the same pathways.

"We found that if we selectively block ghrelin in this part of the brain, we can suppress feeding or the need to seek out food and energy," said Horvath. "It also suggests that perhaps it could interfere with the need to seek out drugs as well."

Horvath said ghrelin, which was originally found to signal in the hypothalamus, has now been shown to have a broad influence on various brain functions. "This makes sense because the major driving force of life is seeking energy to survive," he said. "Future studies will explore the relationships between ghrelin and cocaine addiction."
'"/>

Source:Yale University


Page: 1

Related biology news :

1. Hormones and growth: The control of body size and developmental growth rate in fruit flies
2. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
3. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
4. Low level of extinction during ice age linked to adaptability
5. Improved statistical tools reveal many linked loci
6. Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
7. Attacks of King George IIIs madness linked to key metabolism molecule
8. Gene controlling circadian rhythms linked to drug addiction
9. Physical and functional interaction of key cell growth molecules linked to cancer
10. VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
11. Naturally occurring asbestos linked to lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Hormone linked brain cravings for food and other energy sources

(Date:11/4/2014)... – University of Utah engineers developed the first room-temperature ... produce electricity without needing to ignite the fuel. These ... electronics, off-grid power and sensors. , A study of ... Chemical Society journal ACS Catalysis . , Fuel ... between a fuel and an oxygen-rich source such as ...
(Date:11/4/2014)... about the way our bodies are assembled during early ... they are supposed to become a nerve or a ... correct place and alignment? Researchers at the University of ... a new study, UM researchers describe the signaling systems ... at the head-trunk region. Their discovery may have important ...
(Date:11/4/2014)... of Madagascar,s 101 species of lemurs are threatened with ... rainforests they call home. A new study by Rice ... on rainforest tree populations, which raises concerns about the ... rich biodiversity. , A large proportion of trees in ... in turn disperse the seeds of their fruit trees ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2The inside story: How the brain and skull stay together 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... American Society for Microbiology (ASM) Raymond W. Sarber ... Harvard College, Cambridge, Massachusetts. This award recognizes students ... excellence and potential. Ms. Clapham, currently a ... in the laboratory of Richard Losick, where she ...
... be the first recipient of a prestigious award given by ... Meeting of the Ecological Society of America on August 3. ... an outstanding record of informing their political decision-making with ecological ... figure that has a sharp appreciation for local and global ...
... DCMay 28, 2008The inaugural 2008 American Society for ... is being presented to Mary Ann Moran, Distinguished ... Georgia, Athens. This award honors the late David ... scientific approach and for being a dedicated and ...
Cached Biology News:American Society for Microbiology honors Mary Ann Moran 2
(Date:11/26/2014)... , Nov. 25, 2014 Bio-Techne Corporation ... has appointed Robert Gavin to serve in ... the Protein Platforms Division.  Mr. Gavin will be responsible ... segment, which includes the ProteinSimple business acquired in July ... San Jose, California -based ProteinSimple develops ...
(Date:11/24/2014)... -- IGI Laboratories, Inc. (NYSE MKT: IG), a ... today announced it has submitted an additional abbreviated new ... Administration (FDA), which brings the Company,s total number of ... now pending at the FDA. ... commented, "Our team here at IGI has continued to ...
(Date:11/24/2014)... , Belgium , Nov. 24, 2014 ... sciences company focused on developing diagnostic tests for cancer and ... cancer study will be presented at the Science for Business ... Belgium . The data come from VolitionRx,s ... at the Pneumology department of the Centre Hospitalier Universitaire (CHU) ...
(Date:11/24/2014)... One of the most extensive, widely cited digital ... now available to high school and junior college students and ... international society for optics and photonics , announced today that ... Library available to high schools for free and two-year ... to all areas of life in today’s world,” said SPIE ...
Breaking Biology Technology:Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 2Bio?Techne Announces Appointment Of Robert Gavin As Leader Of New Protein Platforms Division 3IGI Laboratories, Inc. Announces ANDA Submission 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 2VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 3VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 4VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 5VolitionRx to Present Positive Data from Pilot Lung Cancer Study at BioWin Day 2014 6SPIE Digital Library Now Available to High Schools, Two-Year Colleges at No or Low Cost 2
... Mass., June 17 Genzyme Corporation,(Nasdaq: GENZ ... applications,in both the United States and the European ... enhance mobilization of,hematopoietic stem cells for collection and ... myeloma. The company,has requested priority review of its ...
... - Improved Technology Will Provide the Early Detection Critical to ... IPN Viral Spread in Fish Farms and Wild ... SANTIAGO, Chile, June,17 ZyGEM Corp Ltd. and DIAGNOTEC S.A. ... diagnostics for the,detection of infectious pancreatic necrosis virus (IPNV), a ...
... Netherlands, June 17 , - Equens and Albert ... processor Equens and supermarket chain Albert Heijn,will begin a ... a period of,six months, customers of Albert Heijn will ... The objective of the pilot is to,investigate the potential ...
Cached Biology Technology:Genzyme Files Applications for Approval of Mozobil in the United States and Europe 2Genzyme Files Applications for Approval of Mozobil in the United States and Europe 3Genzyme Files Applications for Approval of Mozobil in the United States and Europe 4Genzyme Files Applications for Approval of Mozobil in the United States and Europe 5ZyGEM and DIAGNOTEC Collaborate on Diagnostics for Detecting a Devastating Virus Attacking Salmon 2ZyGEM and DIAGNOTEC Collaborate on Diagnostics for Detecting a Devastating Virus Attacking Salmon 3Start of First Fingertip Payment Pilot in the Netherlands 2Start of First Fingertip Payment Pilot in the Netherlands 3
... to Taura Syndrome Virus Coat ... all tested applications). ... VTNSEGSTIL MNDIPITNQN VVLSKNVTDN LFEVQDQALI ESLSRDVLLH ... N terminal amino acids 25/100 ...
Anti-rat Dipeptidyl Peptidase IV (DPP IV), CD26, Clone 5E8, Monoclonal Antibody...
Purified Mouse anti-Hu Actopaxin (pS8) Storage Temperature: Refrigerate(2 to 8C)...
... 4) Immunogen: KLH-conjugated, ... K]Q... in which [ Ac K] corresponds ... H3 Accession Number: ... Mr ~17kDa Quality Assurance: ...
Biology Products: