Navigation Links
Hormone linked to brain's cravings for food and other energy sources

Ghrelin, a hormone produced in the stomach, induces food intake and operates through a brain region that controls cravings for food and other energy sources, researchers at Yale School of Medicine report in the October 19 online issue of The Journal of Clinical Investigation.

Ghrelin was previously associated with growth hormone release, appetite, learning, and memory and has now been linked with the reward circuitry of the brain that regulates food cravings.

According to lead author Tamas Horvath, components of the reward circuitry of the ventral tegmental area (VTA), may be responsible for overeating and addiction. "Targeting this region pharmacologically is an interesting tool to explore," said Horvath, chair of the Section of Comparative Medicine at Yale School of Medicine and professor of comparative medicine, neurobiology and obstetrics, gynecology & reproductive sciences.

In this study, Horvath and colleagues found that ghrelin could signal directly in the VTA region and activate dopamine neuronal activity, which controls reward-associated behavior to promote interest in food as a reward. As a default, ghrelin's action may also alter seeking of drugs and substances that work through the same pathways.

"We found that if we selectively block ghrelin in this part of the brain, we can suppress feeding or the need to seek out food and energy," said Horvath. "It also suggests that perhaps it could interfere with the need to seek out drugs as well."

Horvath said ghrelin, which was originally found to signal in the hypothalamus, has now been shown to have a broad influence on various brain functions. "This makes sense because the major driving force of life is seeking energy to survive," he said. "Future studies will explore the relationships between ghrelin and cocaine addiction."
'"/>

Source:Yale University


Page: 1

Related biology news :

1. Hormones and growth: The control of body size and developmental growth rate in fruit flies
2. Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
3. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
4. Low level of extinction during ice age linked to adaptability
5. Improved statistical tools reveal many linked loci
6. Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
7. Attacks of King George IIIs madness linked to key metabolism molecule
8. Gene controlling circadian rhythms linked to drug addiction
9. Physical and functional interaction of key cell growth molecules linked to cancer
10. VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
11. Naturally occurring asbestos linked to lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017 /PRNewswire/ ... leader in dairy research, today announced a new collaboration ... reduce the chances that the global milk supply is ... dairy project, Cornell University has become the newest academic ... Supply Chain, a food safety initiative that includes IBM ...
(Date:5/6/2017)... 5, 2017 RAM Group , ... new breakthrough in biometric authentication based on a ... properties to perform biometric authentication. These new sensors are ... created by Ram Group and its partners. This sensor ... supply chains and security. Ram Group is a ...
(Date:4/13/2017)... UBM,s Advanced Design and Manufacturing event in ... and evolving technology through its 3D Printing and Smart ... the expo portion of the event and feature a ... on trending topics within 3D printing and smart manufacturing. ... will take place June 13-15, 2017 at the Jacob K. ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... International research firm Parks Associates announced today that Tom ... 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase Driver ... "The residential security market has experienced continued growth, and ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... optimization firm for the life sciences and healthcare industries, announces a presentation by ... Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present ...
(Date:10/9/2017)... , Oct. 9, 2017  BioTech Holdings ... mechanism by which its ProCell stem cell therapy ... limb ischemia.  The Company, demonstrated that treatment with ... of limbs saved as compared to standard bone ... molecule HGF resulted in reduction of therapeutic effect.  ...
(Date:10/9/2017)... , ... October 09, 2017 , ... At its national ... Christopher Stubbs, a professor in Harvard University’s Departments of Physics and Astronomy, has been ... a member of the winning team for the 2015 Breakthrough Prize in Fundamental physics ...
Breaking Biology Technology: