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Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients

st both HIV proteins. The dose of ceftriaxone needed for protection was well within the range currently used for treatment of bacterial infections.

"These results indicated that this class of drugs may prove effective in treating HIV patients with dementia," Rumbaugh says.

About 500,000 people in the United States alone have HIV dementia. And although new cases of HIV dementia have declined over the last 10 years (due to the increased availability of effective HIV treatments), the prevalence of HIV dementia is on the rise since people are living longer with HIV.

"We hope this research might help many patients with other forms of dementia, such as Alzheimer's, and infections of the brain, like herpes encephalitis and West Nile encephalitis," says Rumbaugh. "However, it will require a lot more development before drugs like these can be used even to treat patients with HIV dementia, let alone to treat patients with other neurological diseases."


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Source:Johns Hopkins Medical Institutions


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