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High-dose flu vaccines appear to safely boost immunity in elderly

received the 60 ìg dose than among those who received the 15 ìg dose, most reactions to the immunization were mild.

Although current vaccines are sufficient to protect younger adults from influenza, the elderly and others at high risk of hospitalization and death from the disease have not responded consistently, the authors write. "Improved vaccines are needed to reduce the morbidity and mortality associated with influenza in these vulnerable populations," they write. "Increasing the dose of inactivated influenza vaccine consistently and safely increases the immunogenicity [immune response] of inactivated influenza virus vaccines; moreover, vaccines that contain higher doses have conferred significantly enhanced protection against naturally occurring influenza."


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Source:JAMA and Archives Journals


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