Navigation Links
Heavy smoking cuts women's chance of pregnancy -- even with donated oocytes

f its effect on ovarian function, and this is a new finding."

Although the pregnancy rate was much lower in heavy smokers, for those that did become pregnant the multiple pregnancy rate was much higher, with 60% of the heavy smokers expecting twins against 31% of the non-heavy smokers.

"This is counter-intuitive," said Dr Soares, "and although we controlled for all known interfering variables, it is possible this is not a real association. What would confirm it as a real association is to find it still applies in a large number of cases. However, if it is confirmed as a real association it suggests that, paradoxically, tobacco constituents affect the uterus in different ways in different women, impairing implantation in some and having the opposite effect in others.

"It is already known that there is paradoxical dose-dependent effect of nicotine on ovarian tissue. Maybe the same effect is happening in uterine tissue. The effect of a certain molecule depends, not only on its concentration, but also on the concentration of its receptors and all the other molecules present in the cell. It could be that heavy smoking disrupts the stability of cells in the lining of the uterus differently in some women to others or triggers a response in the embryo itself, resulting in a reduced general pregnancy rate overall, but an increased chance of multiple pregnancy in those who do become pregnant."

Dr Soares said, that as well as confirming these findings in higher numbers of heavy smokers who use donated oocytes, it would be worthwhile studying differences in gene expression in the lining of the uterus of heavy smokers who fail to get pregnant and those whose have twins.

But, for now, the clinical implications of the findings were clear. Tobacco makes the uterus less likely to accept an embryo.

"In spite of all the noise generated about the effects of smoking in a series of health areas, its possible effect on uterin
'"/>

Source:European Society for Human Reproduction and Embryology


Page: 1 2 3

Related biology news :

1. Heavy multivitamin use may be linked to advanced prostate cancer
2. Research shows smoking adds a decade to reproductive age of IVF patients
3. OHSU research shows vitamin C counteracts some negative impacts of smoking on unborn babies
4. Indias smoking gun: Dino-killing eruptions
5. Alcoholism, smoking and genetics among Plains American Indians
6. Both alcoholism and chronic smoking can damage the brains prefrontal cortex
7. Researchers test new way to quit smoking
8. Blood test predicts success of quitting smoking using the nicotine patch
9. Quitting smoking improves lung function considerably
10. Cigarette smoking impedes tendon-to-bone healing
11. High HPV concentrations combined with smoking significantly raise risks of cervical cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Heavy smoking cuts women chance pregnancy even with donated oocytes

(Date:8/28/2014)... MARC (Maximizing Access to Research Careers) Program has ... Society of America,s 27th Annual Mouse Molecular Genetics ... in Pacific Grove, California. These awards are ... doctorates and scientists from underrepresented groups into the ... encourage the participation of young scientists at the ...
(Date:8/28/2014)... N.C. -- Scientists have identified the developmental on-off switch ... that produce more than two-thirds of the world,s naturally ... be to see whether it is possible to manipulate ... , The study, appearing August 28 in ... small molecule called cyclic-di-GMP and a larger protein called ...
(Date:8/28/2014)... that could positively impact the global battle ... thanks to researchers in Penn State,s College ... made from the seaweed-derived food ingredient carrageenan ... provides a woman-initiated, drug-delivery vehicle that can ... infections during unprotected heterosexual intercourse, the researchers ...
Breaking Biology News(10 mins):Small molecule acts as on-off switch for nature's antibiotic factory 2Small molecule acts as on-off switch for nature's antibiotic factory 3Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 3
... One hundred million years ago the earth looked very different ... breaking apart, dinosaurs were roaming the earth, and flowering plants ... known as Gondwana formed around 180-200 mya during the breakup ... mya. As scientists reconstruct the history of these land masses ...
... -- In a significant step toward restoring healthy blood ... of scientists at Weill Cornell Medical College has developed ... turning human embryonic and pluripotent stem cells into plentiful, ... of blood vessels. Endothelial cells form the interior "lining" ...
... Technologies Inc. (COTI) (TSX Venture: COT)announced more positive results ... Canadian cancer research facility. This new series of experiments ... efficacy both as a single agent and in combination ... toxicity in several different animal models of human ...
Cached Biology News:Can modern-day plants trace their New Zealand ancestry? 2New way to generate abundant functional blood vessel cells from human stem cells discovered 2New way to generate abundant functional blood vessel cells from human stem cells discovered 3New way to generate abundant functional blood vessel cells from human stem cells discovered 4Oral COTI-2 is effective in a second animal model of human pancreatic cancer 2
(Date:8/28/2014)... Washington, USA (PRWEB) August 27, 2014 ... next month for SPIE Laser Damage 2014 ... optical materials for high-power lasers will run 14-17 September. ... society for optics and photonics . , The premier ... for understanding laser damage to optical materials will engage ...
(Date:8/28/2014)... Whitehouse Laboratories is excited to announce that ... PTI Inspection Systems that will enable it to ... leak testing method development and validation programs using the ... part of this agreement, Whitehouse Labs has taken delivery ... developed and manufactured by PTI. The HVLD (high ...
(Date:8/27/2014)... , Aug. 27, 2014 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p02316661/Global-Biodegradable-Packaging-Materials-Market-2014-2018.html ... materials that are readily decomposed by the ... conventional non-degradable packaging in terms of raw ...
(Date:8/27/2014)... , Aug. 27, 2014 Research ... "Global Lactic Acid  (Biodegradable Polymer, Food & ... & Forecasts to 2019" report to their ... hydroxyl-carboxylic acid with an asymmetrical carbon atom. The ... biodegradable polymer, food and beverage, personal care product, ...
Breaking Biology Technology:Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 2Laser Damage to Draw Researchers, Engineers, Scientists to 46th Annual Conference 3Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Global Biodegradable Packaging Materials Market 2014-2018 2Global Biodegradable Packaging Materials Market 2014-2018 3Global Biodegradable Packaging Materials Market 2014-2018 4Global Biodegradable Packaging Materials Market 2014-2018 5Global Biodegradable Packaging Materials Market 2014-2018 6Global Biodegradable Packaging Materials Market 2014-2018 7Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2
... Diabetes, BRUSSELS, October 13 The International Diabetes,Federation ... opinion,leaders to push for action to secure care for ... access to care., The meeting, Access to Essential ... held on Saturday, October 25 in London, United,Kingdom. The ...
... 13 Thursday and Friday of,last week saw continued ... As anticipated in the Company,s October 9th news release, ... sales of shares,beneficially owned by Boston Scientific,s co-founders Pete ... market on Friday, approximately 31,million shares in aggregate had ...
... WebLOQ, Inc., the emerging,leader in total privacy ... communications, today announced that Monterey Spine and,Joint ... their state-of-the-art,Monterey center. The center, along with ... and other local practices, has,implemented WebLOQ,s hosted, ...
Cached Biology Technology:International Diabetes Federation Calls for Global Action to Keep All Children With Diabetes Alive 2International Diabetes Federation Calls for Global Action to Keep All Children With Diabetes Alive 3Boston Scientific Provides Update on Involuntary Selling of Its Stock by Co-Founders 2Boston Scientific Provides Update on Involuntary Selling of Its Stock by Co-Founders 3Monterey Spine and Joint Deploys WebLOQ ePrivacy Solution for HIPAA Compliant Health Information Exchange 2Monterey Spine and Joint Deploys WebLOQ ePrivacy Solution for HIPAA Compliant Health Information Exchange 3
... Reverse Transcriptase (M-MLV RT) is an RNA-dependent DNA ... with long messenger RNA templates (>5kb). The enzyme ... M-MLV and consists of a single subunit with ... activity of M-MLV RT is weaker than the ...
... Useful for the determination of digitonin and digoxin. ... EDTA Na 4 and 0.06% NaCl Preparation ... al., Biochem. Biophys. Res. Commun., 19, 755 ... mole of inorganic phosphorus from ATP per min ...
kismet (dK-20)...
... Thermo Hybaid's unique Electro-4 design allows ... the Electro-4 it is possible to run ... tank, by stacking up to four,horizontal gels. ... adjustable according to the number of gels ...
Biology Products: