Navigation Links
HIV vaccine takes different tack to boosting immune response

mmune responses," said Chen. "In most cases, we found a significant enhancement in both antibody and T-cell response by inhibiting SOCS1."

Chen hopes this immunization approach of inhibiting SOCS1 will help develop more effective prophylactic as well as therapeutic vaccines. Therapeutic vaccines may contribute to the long-term control of HIV infection and will relieve HIV patients of their heavy dependence on antiretroviral drugs, many of which are expensive and require daily administration.

"Conventional wisdom is that natural immune responses play an important but insufficient role in controlling HIV infection," said Chen. "Hopefully this therapeutic vaccine can boost the natural immune responses strong enough so you don't have to take these anti-HIV drugs all the time."

Chen anticipates testing the HIV vaccine in humans in the next several years. He foresees the SOCS1 silencing strategy enhancing therapeutic and prophylactic vaccines against other pathogens in addition to HIV.

Drs. Xiao-Tong Song and Kevin Evel-Kabler, both postdoctoral associates at BCM's Center for Cell and Gene Therapy, also contributed to the study.


'"/>

Source:Baylor College of Medicine


Page: 1 2

Related biology news :

1. Research advances quest for HIV-1 vaccine
2. A much-needed shot in the arm for HIV vaccine development
3. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
4. Gene vaccine for Alzheimers disease shows promising results
5. Influenza vaccine uses insect cells to speed development
6. Norovirus, AIDS vaccine and Hepatitis Virus
7. HIV vaccine trial breaks ground for future research
8. Live vaccines more effective against horse herpes virus
9. NIAID begins clinical trial of West Nile virus vaccine
10. Designing vaccines by computer
11. Wake Forest scientists find new combination vaccine effective against plague

Post Your Comments:
(Date:11/20/2009)..., Toxic dust: Toxins in coal-tar-based sealcoat...ed house dust, according to a USGS study. PAHs o...cules found in oil, coal and tar deposits, and can...s are often found in house dust; however, the spec...d. Researchers found that dust from indoor areas n...
(Date:11/20/2009)...ussel, November 19th 2009 - Bacteria possess an in...ng the building blocks of the cell. This is the ne...ris Messens of VIB, a life sciences research insti...Universiteit Brussel. The scientists made this dis...erium Escherichia coli . By means of this model o...
(Date:11/20/2009)...rplus biomass from the production of flax shives, ...lowered plant related to those which engulf fields...s has been suggested by two studies carried out by...e journal Renewable and Sustainable Energy Review...tal point of view, the production of bioethanol fr...
Breaking Biology News(10 mins):From toxic dust and algae to ill winds from Africa 2From toxic dust and algae to ill winds from Africa 3From toxic dust and algae to ill winds from Africa 4From toxic dust and algae to ill winds from Africa 5Biologists discover bacterial defense mechanism against aggressive oxygen 2Flax and yellow flowers can produce bioethanol 2Diabetes drug linked to increased risk of heart failure 54955 1Diabetes drug linked to increased risk of heart failure 54955 2LSTM to lead EU project to coordinate antimalarial drug research 54952 1LSTM to lead EU project to coordinate antimalarial drug research 54952 2Swine Flu Vaccine Delay Manageable Experts Say 54949 1Swine Flu Vaccine Delay Manageable Experts Say 54949 2Swine Flu Vaccine Delay Manageable Experts Say 54949 3
... the inefficiency of current irrigation methods. M...ots of crops, amounting to an enormous waste of wa..., however, are investigating a new solution that t...of the issue. They are genetically modifying plant...he water essential to their survival. , The Roo...
...sortium (CLIC), a group of researchers from 10 aca...States and Canada led by physicians at Case Wester...ived a five year, $10.8 million dollar grant from ...ow HIV infection results in the progressive immune...four coordinated projects ranging from basic labor...
...lass of small molecules known as microRNA have bee...ne products in most animal and plant species. A ne...the development of alcohol tolerance, a hallmark o...ted by the National Institute on Alcohol Abuse and...y 31 issue of the journal Neuron . , "This is an...
Other Biology News:Tel Aviv University researchers root out new and efficient crop plants 2Case Western Reserve University School of Medicine researchers receive $10.8 million 2MicroRNA implicated as molecular factor in alcohol tolerance 2
(Date:11/20/2009)..., Nov. 20 Dendreon Corpo....S. Food and Drug Administration (FDA) provided wr...iologics License Application (BLA) for PROVENGE...A has assigned a Prescription Drug User Fee Act (P...espond to Dendreon,s amended BLA. Dendreon is see...
(Date:11/20/2009)...TLE, Nov. 20 Cell Therap...d today that the Ninth Circuit Court of Appeals re...CTI should be allowed to pursue all of its claims ...he District Court for trial. CTI filed a complain... reimbursement consultant for CTI,s product TRISEN...
(Date:11/19/2009)...ld like to be able to charge their cell phones and...ten. A recent discovery made by UC San Diego engin...citors that could do just this. , In recent res...bhakar Bandaru, a professor in the UCSD Department...th graduate student Mark Hoefer, have found that a...
(Date:11/19/2009)..., N.Y., Nov. 19 Dr. Mate Hidvegi, ...esponds to a press release issued on November 17 b...ny for making false and self-serving statements ab..., Dr. Hidvegi stated from his office in Budapest,...ch on Avemar does not apply to AveULTRA, www.ave...
Breaking Biology Technology:Dendreon Receives FDA Acknowledgement of Complete Response 2Dendreon Receives FDA Acknowledgement of Complete Response 3Cell Therapeutics Wins Federal Appeal to Pursue $22.8 Million Claim Against The Lash Group 2Nanotube defects equal better energy and storage systems 2American BioSciences Rebuts Misleading Statements Made by Hungarian Competitor 2
...ty , , BEVERLY, Mass., Jan. 7 Sensitech Inc., ...ns, has launched the TempTale(R)4USB temperature m... This latest model of the industry-leading TempTal... shipment receiving sites without proprietary soft...diary of Carrier Corp., a business unit of United ...
... today announced,a licensing agreement with Teva P...tant publicly-undisclosed generic product, using a...st generic drug manufacturer in the world, is a,le...ct is one of the largest-,selling generic prescrip...greement, Teva would be using the Codexis process ...
...q: ABAX ), a medical products company manufactur...oth the medical and veterinary markets, announced ... for co-exclusive worldwide rights in the field of...ketplace for certain technologies pertaining to la...his license agreement provides Abaxis the co-exclu...
Other Biology Technology:Introducing Sensitech's TempTale(R)4USB Temperature Monitor 2Introducing Sensitech's TempTale(R)4USB Temperature Monitor 3Codexis, Teva in Licensing Agreement Final 2ABAXIS Announces Worldwide Animal Health Licensing Agreement for Rapid Test Technology 2ABAXIS Announces Worldwide Animal Health Licensing Agreement for Rapid Test Technology 3
Xylene Resistant (X/R) Red System, 1000 Tests (SIGNET) from Covance Research Products, Inc
HeLa Cell Slide from ProSci, Inc
Anti-YAP, phospho (Ser127) Antibody, Unconjugated from Cell Signaling Technology
EL4 Cell Slide from ProSci, Inc
Biology Products: