Navigation Links
Group proves it's possible to grow new lung alveoli by growing new blood vessels

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.

It's really a win-lose situation: the babies are saved but they pay the price with dramatically underdeveloped lungs--forcing them to spend their early days outside the womb fighting for every breath. And now, with many of these premature babies reaching their adolescent years, clinicians and researchers are also waiting to see whether longer term health problems are going to begin occurring.

"Right now we simply don't have any treatments," says Bernard Thébaud, a clinician-scientist and neonatologist in the Department of Pediatrics. "So, if we can't prevent it, we've started to think about how we might repair it."

Using animal models, Dr. Thébaud and a team of University of Alberta researchers have taken what they say is the first important step towards a treatment--in effect, growing new blood vessels and alveoli--the tiny air sacs where gas exchange occurs between the lungs and blood vessels--in tiny rat lungs.

The results of their work were recently published in Circulation, entitled Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-Induced Lung Injury: Evidence That Angiogenesis Participates in Alveolarization.

The results have caused a stir in the scientific community: In an accompanying editorial in the October 18 issue of the journal, Kurt Stenmark, a University of Colorado Divisions of Critical Care and Pulmonary Medicine researcher, said the studies "…raise new possibilities for the treatment of infants with severe chronic lung disease. It seems possible that by augmenting or restoring vascular growth, overall lu
'"/>

Source:University of Alberta


Page: 1 2

Related biology news :

1. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
2. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
3. Purdue proves concept of using nano-materials for drug discovery
4. FDA Approves New Drug to Treat Type I and Type II Diabetes
5. Canada approves marijuana-based pain spray
6. Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer
7. Product improves peptide identification for proteomics research
8. FDA Approves New Treatment for Chronic Hepatitis B
9. Stem cell treatment improves mobility after spinal cord injury
10. FDA approves more generic AIDS drugs
11. Experimental shingles vaccine proves effective in nationwide study
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Group proves possible grow new lung alveoli growing new blood vessels

(Date:9/30/2014)... When it comes to using marijuana, new research, involving ... the Journal of Leukocyte Biology , ... mean that you should. That,s because a team of ... may do serious long-term damage to the immune system. ... inflammatory diseases, such as multiple sclerosis, inflammatory bowel disease ...
(Date:9/30/2014)... to know what goes wrong with your muscles because of ... what "normal" actually is. That,s where a new research report ... FASEB Journal comes in. In the report, a ... molecules that can help scientists "see" which genes are active ... found never-before-detected gene activity and that men have approximately 400 ...
(Date:9/30/2014)... is available in German . ... behavioural response to risky situations such as exposure to ... now found in a long-term study on different populations ... metabolic rate and ambient temperature. High metabolic rates and ... in these scenarios birds were more likely to approach ...
Breaking Biology News(10 mins):Adolescent exposure to thc may cause immune systems to go up in smoke 2Scientists identify which genes are active in muscles of men and women 2Risky metabolism 2
... BEER-SHEVA, ISRAEL, August 8, 2012 Ben-Gurion University of ... (290,000) from the Wolfson Family Charitable Trust and Wolfson ... and its environmental impact. According to BGU,s Vice ... two projects are part of the University,s overall commitment ...
... Innovative problem solving requires trying many different solutions. That,s ... that it,s true for hyenas, too. The study, published ... Royal Society B , presented steel puzzle boxes with raw ... the meat, the hyenas had to slide open a bolt ...
... For much of the year drought has been plaguing American ... appear to be losing the turf war against climate when ... State University-led study looked at the drought tolerance of 426 ... to better understand how grasslands in different parts of the ...
Cached Biology News:Diversity keeps grasslands resilient to drought, climate change 2Diversity keeps grasslands resilient to drought, climate change 3
(Date:9/30/2014)... Applying a well-known optical phenomenon called thin-film interference, ... demonstrated the ability to "paint" ultra-thin coatings onto ... for making future, flexible electronic devices, creating advanced ... rocket ships and spacecraft with extremely lightweight decorative ... water, it becomes iridescent, revealing a myriad of ...
(Date:9/30/2014)... analog of one of nature,s most efficient light-harvesting ... led by Alejandro Briseno of the University of ... developing long-sought polymer architecture to boost power-conversion efficiency ... devices. , Briseno, with colleagues and graduate ... University and Dresden University of Technology, Germany, report ...
(Date:9/30/2014)... YORK , Sept. 30, 2014 ... and segments with highest potential revenues Do you ... updated report gives you revenue predictions for those ... For those therapies you find financial data, R&D ... analysis you get sales forecasts to 2024 at ...
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... used to kill nematodes. Nematodes are microscopic parasitic ... soil, water, and inside other plants and animals. ... high volatility or other properties promoting migration through ... contain more than 1,000 plant-parasitic nematodes. With more ...
Breaking Biology Technology:Taking thin films to the extreme 2Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 4Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 5Nematicides Market by Types (Fumigants, Organophosphates, Carbamate and Bio-Nematicides), Applications (Agrochemicals, Industrial, and Others), and Geography (North America, Europe, Asia-Pacific & ROW) - Global Trends & Forecasts to 2019 2
... Workshop Set for Sept. 3, UPPSALA, Sweden and ... Bernard de Bruyne, M.D., Ph.D., will present the,benefits of ... the outcomes of multivessel PCI in a workshop at ... The EBAC-accredited,workshop, which is sponsored by Radi Medical Systems, ...
... Cepheid (Nasdaq:,CPHD) will present at the Thomas Weisel ... Hotel, Boston, September 5 to 7, 2007. Chief,Executive ... Finance and,Chief Financial Officer, John R. Sluis will ... The webcast, along with accompanying presentation slides, may ...
... Verenium,Corporation (Nasdaq: VRNM ), a leading developer of ... high-performance specialty,enzymes, announced today that Carlos A. Riva, President ... the Cowen and Company Clean,Energy Conference. The presentation is ... 6, 2007 and will take place at Le Parker ...
Cached Biology Technology:Interventional Cardiologists Nico Pijls, Bernard De Bruyne to Discuss Benefits of Measuring Coronary Pressure in Improving Multivessel PCI at ESC Congress 2007 2Cepheid to Present at Thomas Weisel Partners Healthcare Conference 2Verenium Corporation to Present at the Upcoming Cowen and Company Clean Energy Conference 2Verenium Corporation to Present at the Upcoming Cowen and Company Clean Energy Conference 3
... Certify products ATP-Free using Mo Bio ... sensitive ATP-Free certification service that will allow you ... level of accuracy and enable you to deliver ... Mo Bios ATP detection limit is 3.5 ...
... Microarrays: Biomedical Photometrics Inc. (Waterloo, Ontario, Canada) ... have collaborated to develop a fluorescence reader ... The DNAscope AT is based on BPIs ... automatically reads up to six ArrayTubes in ...
... a comprehensive kinase analysis service utilizing ... peptide microarrays synthesized on Paraflo microfluidic ... quantitative measurement of kinase kinetic activities, ... service includes preparation of your kinase ...
... The JNK (c-Jun NH2-terminal kinase) ... three identified MAP kinase pathways in ... response to environmental stress, is associated ... itself, and is implicated in the ...
Biology Products: