Navigation Links
Grand Challenges in Global Health initiative funds Yale project

Yale has been offered $17 million from the Grand Challenges in Global health initiative to genetically engineer mice with immune systems similar enough to humans to aid in testing the safety and effectiveness of potential vaccines.

Funded by the Bill & Melinda Gates Foundation, the Yale project will be headed by Richard A. Flavell, M.D., Sterling Professor and Chair of Immunobiology at Yale University School of Medicine, and Howard Hughes Medical Institute investigator.

Flavell and his team will study a novel solution to a problem facing many vaccine developers. Some of the most promising vaccines for HIV and a range of other diseases are made from weakened versions of the infectious agent. These cannot be studied in human trials unless researchers are confident that they are safe.

"A big need in the world of vaccine development is the ability to predict whether vaccines for humans are safe and effective," said Flavell. "We are grateful to the Grand Challenges in Global Health Initiative for providing the funds to develop a predictive model system for vaccine testing."

Yale School of Medicine Dean Robert Alpern, M.D., said, "This generous grant from the Grand Challenges in Global Health Initiative provides a boost to Yale's ongoing initiatives in basic science and clinical research. It will advance research on diseases that have an effect on communities worldwide."

The goal of this award is to provide to the research community a suitable model system to test live attenuated vaccines for use in the developing world. Flavell said the mice generated would be made available to the broader scientific community in order to meet the charitable objectives of the Grand Challenges Initiative. Flavell will collaborate with the Institute for Research in Biomedicine in Switzerland and with Regeneron Pharmaceuticals in Tarrytown, New York.

The team will engineer a mouse model in which critical components of the human immune syste
'"/>

Source:Yale University


Page: 1 2

Related biology news :

1. Measurement Challenges In Detecting Cancer Biomarkers
2. Global analysis of membrane proteins
3. Global warming increases oyster sensitivity to pollution
4. Global study shows all tobacco bad for the heart
5. Global warming may warrant new approaches to ecosystem restoration
6. Global warming may have damaged coral reefs forever
7. Global malaria map key weapon in fight against malaria, scientists say
8. Global changes alter the timing of plant growth, scientists say
9. Global map shows new patterns of extinction risk
10. Global sunscreen has likely thinned, report NASA scientists
11. Global survey of lizards reveals greater abundance of animals on islands than on mainland ecosystems
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Grand Challenges Global Health initiative funds Yale project

(Date:8/21/2014)... previously unknown process for harvesting energy and producing oxygen ... State University scientist has discovered. The discovery lays the ... harvesting energy from the Sun, and understanding dense blooms ... lakes worldwide. A paper describing the discovery will be ... the journal Science on 21 August 2014. ...
(Date:8/21/2014)... A ubiquitous skin fungus linked to dandruff, eczema and ... tracked to even further global reachesincluding Hawaiian coral reefs ... sea vents. , A review in the scientific journal ... distribution of the fungi of the genus Malassezia ... environmental sequencing datasets from around the world. , University ...
(Date:8/21/2014)... intake, health and quality of life of older adults ... the University of Waterloo receiving close to $1.5 million ... (CIHR). , Professor Heather Keller, of the Faculty ... research chair in nutrition and aging, will receive $979,000 ... in long-term care homes are poorly nourished. The project ...
Breaking Biology News(10 mins):Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3From dandruff to deep sea vents, an ecologically hyper-diverse fungus 2Grants will fund landmark aging research at Waterloo 2
... will take place on the campus of the Abdus ... the Academy,s secretariat. TWAS,s new executive director, Romain Murenzi, ... of TWAS; Fernando Quevedo, director of ICTP; Immacolata Pannone, ... TWAS President, will highlight the opening ceremony. The morning ...
... 15, 2011   DigitalPersona, Inc. ... protection solutions, today announced at the CARTES & ... company has open sourced its new MINEX-certified FingerJetFX™ ... (OSE), is free, portable software that device manufacturers ...
... FRANCISCO, CANovember 15, 2011The American Heart Association will ... Emeritus Robert Mahley, MD, PhD, with the 2011 ... on one of Gladstone,s founding cardiovascular scientists. ... that the American Heart Association can give a ...
Cached Biology News:TWAS 22nd General Meeting in Trieste 2DigitalPersona Open Sources New FingerJetFX Biometrics Technology for Mobile Devices, PCs and Servers 2DigitalPersona Open Sources New FingerJetFX Biometrics Technology for Mobile Devices, PCs and Servers 3Gladstone founder receives American Heart Association Distinguished Scientist Award 2
(Date:8/22/2014)... are intensively investigated for application as catalysts, ... and components in photonics and molecular electronics. ... for understanding physical and chemical properties, has ... USA, have demonstrated that high-resolution electron microscopy ... structure in which all gold atoms are ...
(Date:8/22/2014)... Aug. 22, 2014 Research and Markets ... and China Gel Permeation Chromatography (GPC) Industry Report 2014" ... Global and China Gel Permeation Chromatography (GPC) Industry Report ... state of the global gel permeation chromatography industry with ... provides a basic overview of the industry including definitions, ...
(Date:8/22/2014)... Los Angeles (PRWEB) August 22, 2014 ... for age-defying products, is in the spotlight again. ... night cream and its NeriumFirmTM Body Contouring Cream ... presented by Backstage Creations during the 66th Primetime ... the patented NAE-8® extract, third-party clinical trials show ...
(Date:8/21/2014)... N.Y. , Aug. 21, 2014  BioSpecifics ... biopharmaceutical company developing first in class collagenase-based products ... or CCH) in the U.S. and XIAPEX ® ... significant results from a randomized, double-blind Phase 2a ... cellulite, or edematous fibrosclerotic panniculopathy. The results showed ...
Breaking Biology Technology:A breakthrough in imaging gold nanoparticles to atomic resolution by electron microscopy 2Global and China Gel Permeation Chromatography (GPC) Industry Report 2014 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5
... communications system. Image courtesy of GE Healthcare. Wisconsin ... include $10 million for a grant and loan program ... systems. , ,"I am committed to ensuring that all ... why I am pleased to unveil a proposal of ...
... and Minnesota students will get a one-of-a-kind experience today ... the International Space Station Expedition 10 crew. , ,The ... EST today at Crossroads Elementary School, St. Paul, Minn. ... Leroy Chiao and Flight Engineer Salizhan Sharipov. Nearly 700 ...
... human embryos. , ,This weeks announcement out of Kings ... the sheep, has been granted a license by the British ... hopes among disease sufferers, scientists and advocacy groups for a ... (ALS). , ,These diseases could be addressed through research on ...
Cached Biology Technology:Doyle proposes $10M to expand use of electronic medical records 2Doyle proposes $10M to expand use of electronic medical records 3Human cloning plans get blessing from British government 2Human cloning plans get blessing from British government 3
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
...
... kits are designed to rapidly and ... using our patented APA Technology. APAgene ... an extraordinarily competitive price. All necessary ... The Locator Kit can be used ...
... designed to deparaffinize and perform Heat Induced ... tissue sections mounted on glass microscope slides. ... at the high temperature used in HIER ... the paraffin by detergent. Formaldehyde fixation impairs ...
Biology Products: