Navigation Links
Gov't Creates Gene Database of Normal Human Tissues

l will match up with the known gene samples, like two pieces of Velcro attaching to each other. The cellular genes are treated with fluorescence and literally light up the gene dots on the chip. The light pattern is then measured with a special type of microscope and the results are fed into a computer for analysis.

Gene expression microarrays have been used in numerous applications, including identifying novel genes associated with certain cancers, classifying tumors, and predicting patient outcome. Another NCI-funded study recently demonstrated that microarray analysis of identical tissue samples at geographically separate laboratories can produce the same quality of results as those done within a single lab**. The normal organ database takes that one step further, enabling scientists and clinicians to compare the gene expression results for their own tissue or genes of interest to a baseline standard that represents a generic picture of normal gene activity, organ by organ, in the human body. Users of the array on the new NCI web site (http://home.ccr.cancer.gov/oncology/oncogenomics/) will find expression profiles for 18,927 genes, which include most of the genes that are known to help direct basic activities of the human body.

Recently the Human Genome Project revealed a surprisingly low number of human genes (20,000-25,000), and Khan said it had been previously reported that "only a fraction of that, perhaps 10,000 genes, are actively transcribed in normal cell processes." Thus it becomes strategically useful to characterize this essential backdrop. "The normal organ database provides a platform that may help scientists find new targets in the cells of previously incurable cancers. The driving force of research in our section is to translate genomic information to the clinic. The goal is to save lives and improve the quality of life for children with high-risk cancer."

Until now, no publicly available, normal human organ database has us
'"/>

Source:NIH


Page: 1 2 3 4

Related biology news :

1. PANTHER Protein Classification System Database 5.0
2. Software Tool for Converting Scientific Text into a Database of Functional Relationships
3. IMF Launches World’s First DNA Database for Myeloma Patients
4. Leptin-signaling Protein Maintains Normal Body Weight And Energy Balance In Mice
5. Normal chromosome ends elicit a limited DNA damage response
6. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
7. New Clues Add 40,000 Years to Age of Human Species
8. Human Cells Filmed Instantly Messaging for First Time
9. Analysis Of Human Genome To Predict The Development Of Illnesses
10. Human Eggs Can Develop From Ovarian Surface Cells In Vitro
11. Determining The Fate Of Cells In The Human Body
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gov Creates Gene Database Normal Human Tissues

(Date:5/23/2013)... tight wrapping of genomic DNA around nucleosomes in ... expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich ... to be locally displaced from nucleosomes for transcription. ... stored in the cell nucleus, wrapped around disk-shaped ... of four different histone proteins and accommodating two ...
(Date:5/23/2013)... unnecessarily undergo surgery or harsh treatments because science ... aggressive forms of the disease. Researchers at Case ... are developing technology that allows patients to safely ... treatments or take drastic measures. , The project ... professor of biomedical engineering at Case Western Reserve ...
(Date:5/23/2013)... medics have succeeded in treating cerebral palsy with autologous ... damage, a 2.5 year old boy had been in ... survival. Just two months after treatment with the cord ... the following months, the child learned to speak simple ... from a Korean study, dispel the long-held doubts about ...
Breaking Biology News(10 mins):Biochemistry: Unspooling DNA from nucleosomal disks 2Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3First successful treatment of pediatric cerebral palsy with autologous cord blood 2
... new understanding of the process cells use to ensure ... copy of each chromosome ?a process that must be ... mental retardation. The new work reveals how gluelike protein ... of meiosis ?the specialized cell division process that produces ...
... calpain can be the key either preventing or promoting the ... "This work provides proof in principle that pharmacological inhibition of ... where this is not desirable, such as in neuronal cells ... in cancer cells where this is clearly a very desirable ...
... rat under stress and what does it do? It ... suffer nontraumatic stress they often head for the refrigerator, ... are normally solitary, are placed in a group-living situation, ... for Behavioral Neuroscience at Georgia State University are using ...
Cached Biology News:What controls stickiness of 'smart' chromosomal glue 2What controls stickiness of 'smart' chromosomal glue 3What controls stickiness of 'smart' chromosomal glue 4Protein's role in regulating cell death sets direction for cancer research 2Just like us, social stress prompts hamsters to overeat, gain weight 2Just like us, social stress prompts hamsters to overeat, gain weight 3Just like us, social stress prompts hamsters to overeat, gain weight 4
(Date:5/23/2013)... , May 23, 2013 BioTrends Research ... advisory firms for specialized biopharmaceutical issues, finds that, ... infectious disease specialists reported that in the past ... intentionally delaying treatment) in anticipation of the next ... months ago, when only 6 percent reported that ...
(Date:5/23/2013)... 2013 Z Trim Holdings, Inc. (OTC Markets: ... variety of industries, announced that Chef Erin ... this year,s National Restaurant Association ("NRA") NRA Show, which ... the Research Chefs Association.  Chef Ryan spoke on the ... Bad and the Ugly," joining four other prestigious panelists ...
(Date:5/23/2013)... The New Jersey chapter of the largest organization ... (BDPA), is hosting its 10th annual Families in Technology ... will encourage students and their parents to explore the ... many of the industries’ finest teachers. Held from 9 ... of Technology, the event will include workshops, instruction and ...
(Date:5/23/2013)...  Verenium Corporation (Nasdaq: VRNM ), a ... commercialization of high-performance enzymes, today announced that ... at two upcoming conferences. (Logo: http://photos.prnewswire.com/prnh/20120924/MM79973LOGO ... Second Annual Marcum LLP Microcap Conference on Thursday, May ... York City.  The presentation is scheduled to begin at ...
Breaking Biology Technology:The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2Verenium To Present At Two Upcoming Conferences 2Verenium To Present At Two Upcoming Conferences 3
... The mini incubation trays ... used to screen antigens that ... membrane. Each tray has eight ... channels that accommodate strips cut ...
... GenomeLab GeXP Genetic Analysis System provides high-throughput, ... PCR*. The systems patented priming strategy ... PCR analysis to just a few genes ... more genes per reaction and more samples ...
... Kit is a simple high performance method ... Removes detergents without significant dilution of protein ... on the Detergent-OUT Spin column and collect ... are suitable for removing detergent from a ...
... are derived from Paraffin embedded tissue blocks, ... procedures to ensure the highest quality. Tissues ... one block, sectioned at a thickness of ... Sections are large (3-5 mm in diameter) ...
Biology Products: