Navigation Links
Gold nanoparticles prove to be hot stuff

Gold nanoparticles are highly efficient and sensitive "handles" for biological molecules being manipulated and tracked by lasers, but they also can heat up fast--by tens of degrees in just a few nanoseconds--which could either damage the molecules or help study them, according to scientists at JILA, a joint institute of the National Institute of Standards and Technology (NIST) and University of Colorado at Boulder.

Biophysicists often study nanoscale and even picoscale mechanics by using lasers to both apply force to and track the position of fragile biomolecules such as DNA or protein by manipulating a tiny sphere--typically polystyrene--attached to the molecule. The JILA team would like to find new microsphere materials that can be trapped by laser radiation pressure more efficiently, which would enable faster measurements and detection of smaller motions at the same laser power. As described in the Aug. 15 issue of Optics Letters,* the JILA team demonstrated that 100-nanometer-wide gold beads, as expected because of their metallic nature, can be trapped and detected six times more easily than polystyrene particles of a similar size.

However, the scientists also found that gold absorbs light and heats up quickly, by a remarkable 266 degrees (Celsius) per watt of laser power, at the wavelength most often used in optical traps. Unless very low laser power is used, the heat could damage the molecules under study. Thus, gold beads would not be useful for temperature-sensitive experiments or applying force to molecules. But the heating effect could be useful in raising local temperatures in certain experiments, such as heating a protein just enough to allow scientists to watch it unfold, the paper suggests.


'"/>

Source:National Institute of Standards and Technology (NIST)


Page: 1

Related biology news :

1. Probing the promise and perils of nanoparticles
2. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
3. Using nanoparticles, in vivo gene therapy activates brain stem cells
4. NJIT study shows nanoparticles could damage plant life
5. Gold nanoparticles could improve antisense cancer drugs
6. MIT nanoparticles may help detect, treat tumors
7. Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?
8. Electric jolt triggers release of biomolecules, nanoparticles
9. U-M researchers use nanoparticles to target brain cancer
10. Widely used iron nanoparticles exhibit toxic effects on neuronal cells
11. Coated nanoparticles solve sticky drug-delivery problem
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gold nanoparticles prove hot stuff

(Date:5/23/2013)... National Laboratory honored more than 165 staff for ... at PNNL,s annual Intellectual Property Commercialization Recognition & ... Energy national laboratory named materials scientist Jun Liu ... battery materials that can store large amounts of ... reduce the time it takes to charge cell ...
(Date:5/23/2013)... suppresses lipid synthesis in the liver, UC Irvine endocrinologists ... liver diseases. , With this finding, Dr. Ellis ... in the field. Study results appear in the May ... , "The dogma in the steroid receptor field for ... the nucleus respond to steroid hormones by regulating genes ...
(Date:5/23/2013)... unnecessarily undergo surgery or harsh treatments because science ... aggressive forms of the disease. Researchers at Case ... are developing technology that allows patients to safely ... treatments or take drastic measures. , The project ... professor of biomedical engineering at Case Western Reserve ...
Breaking Biology News(10 mins):PNNL staff recognized for scientific accomplishments, moving technologies into the marketplace 2UCI study reveals new mechanism for estrogen suppression of liver lipid synthesis 2Using big data to identify prostate cancers and best treatments 2Using big data to identify prostate cancers and best treatments 3
... Implanted devices intended to optimize the cardiac function of ... which patients might be at higher risk of dying ... University Medical Center. , Besides maintaining optimal electrical stimulation ... defibrillation) devices are giving cardiologists a new view of ...
... of the fittest affect every organism on Earth, even ... ones to parasite infections; scientists just uncovered why it ... it while migrating long distances, so they can't propagate ... little-studied outcome of animal migration is whether these long ...
... radiotherapy, on a cellular scale. Antibodies coupled to radioactive isotopes ... that you can find something different on the cell surface ... as it sounds. , A new form of treatment ... traditional chemotherapy with fewer side effects caused tumors to shrink ...
Cached Biology News:Implanted Devices Detect High-Risk Heart Failure Patients 2Implanted Devices Detect High-Risk Heart Failure Patients 3New Treatment Rivals Chemotherapy For Lymphoma, Study Finds 2New Treatment Rivals Chemotherapy For Lymphoma, Study Finds 3
(Date:5/24/2013)... 2013 Many factors impact tissues targeting ... efflux transporters at the blood-tissue barrier. Even when tissue ... fractions in the tissue rather than the total tissue ... is required to guide lead optimization, predict in vivo ... variables that may impact the likely human clinical dose. ...
(Date:5/24/2013)... May 24, 2013 Quincy Bioscience, ... and development of calcium-binding proteins to support healthy ... safety assessment study of apoaequorin in ... published for the British Industrial Biological Research Association. ... to investigate potential adverse effects, if any, of ...
(Date:5/23/2013)... Venaxis, Inc. (Nasdaq:   APPY), an ... clearance and commercializing its rapid, protein biomarker-based appendicitis test, ... underwritten public offering of 10,000,000 shares of its common ... its common stock at an exercise price of $1.36 ... $1.25 per share and related warrant.  Venaxis has also ...
(Date:5/23/2013)... May 23, 2013 Graphite Metallizing ... self-lubricating bushings mounted in stainless steel pillow blocks. ... of GRAPHALLOY with the application and installation versatility ... Pillow Blocks work exceptionally well when submerged ... hostile liquids such as acids, alkalies, hydrocarbons, black ...
Breaking Biology Technology:DMPK for Targeted Tissue Delivery: Solutions for the Most Challenging Part of Outsourcing, New Life Science Webinar Hosted by Xtalks 2Safety Assessment Study of Apoaequorin Published in Food and Chemical Toxicology 2Venaxis Announces Pricing of Offering of Common Stock and Warrants 2Venaxis Announces Pricing of Offering of Common Stock and Warrants 3Graphite Metallizing Now Offers GRAPHALLOY® Stainless Steel Pillow Blocks for Success in Submersible Applications 2Graphite Metallizing Now Offers GRAPHALLOY® Stainless Steel Pillow Blocks for Success in Submersible Applications 3
... online music market continues to surge as Musicnotes, Inc. ... announced that its sales increased 45 percent in 2006 to ... first full year operating profit in 2006, said it sold ... customers. , ,It also has started strong in 2007. Year-to-date ...
... of an audit into state information technology projects nears, the ... ,According to a report in the Milwaukee Journal Sentinel ... decided to stop work on a new automated system that ... Enhanced Automated Benefits Legal Enterprise Services, or EnABLES, was supposed ...
... of the mega hits of the Internet video era is Chad ... Yonda and Matt Sloan. The series tracks the sometimes pathetic life ... shift manager at Empire Foods. , ,This homegrown series may not ... reported seven million views on YouTube , a site through ...
Cached Biology Technology:State of Wisconsin dumps another tech project 2Emergence of Internet video is changing the regulatory landscape 2Emergence of Internet video is changing the regulatory landscape 3Emergence of Internet video is changing the regulatory landscape 4
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
PGD2-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry....
ANTI GELSOLIN...
MOUSE ANTI BOVINE CD335:ALEXA 488 Immunogen: Fusion protein consisting of the extracellular region of bovine CD335....
Biology Products: